2-[1-(2-fluorophenyl)ethylidene]hydrazinecarbothioamide | 149634-41-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[1-(2-fluorophenyl)ethylidene]hydrazinecarbothioamide
• 英文别名: 2-(1-(2-fluorophenyl)ethylidene)hydrazinecarbothiomide；N'-[1-(2-fluorophenyl)ethylideneamino]carbamimidothioic acid
• CAS: 149634-41-3
• 化学式: C₉H₁₀FN₃S
• mdl: MFCD21101630
• 分子量: 211.263
• InChiKey: SYTQZZSJLXTVMO-UHFFFAOYSA-N

物化性质

• 沸点：
  324.9±44.0 °C(Predicted)
• 密度：
  1.27±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.111
• 拓扑面积：
  82.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  二苯二氯硅烷 、 2-[1-(2-fluorophenyl)ethylidene]hydrazinecarbothioamide 在 1.) K 作用下， 生成 [[N'-[1-(2-fluorophenyl)ethylideneamino]carbamimidoyl]sulfanyl-diphenylsilyl] N'-[1-(2-fluorophenyl)ethylideneamino]carbamimidothioate
  参考文献：
  名称：

  Saxena, Chitra; Singh, R. V., Phosphorus, Sulfur and Silicon and the Related Elements, 1994, vol. 97, # 1-4, p. 17 - 26

  摘要：

  DOI：
• 作为产物：
  描述：

  2'-氟苯乙酮 、 氨基硫脲 在 sodium acetate 作用下， 以 乙醇 为溶剂， 反应 0.75h， 生成 2-[1-(2-fluorophenyl)ethylidene]hydrazinecarbothioamide
  参考文献：
  名称：

  Saxena, Chitra; Singh, R. V., Phosphorus, Sulfur and Silicon and the Related Elements, 1994, vol. 97, # 1-4, p. 17 - 26

  摘要：

  DOI：

文献信息

• Spectroscopic Characterization and Biological Potential of Palladium(II) Complexes of Benzylidenehydrazinecarboxamide or -carbothioamide
  作者：Nighat Fahmi、Chitra Saxena、Ranvir V. Singh

  DOI：10.1246/bcsj.69.963

  日期：1996.4

  the synthesis, stereochemistry, and biochemical behavior of palladium(II) complexes of benzylidenehydrazinecarboxamide or -carbothioamide is presented. The bimolar addition and substitution products have been characterized by elemental analyses, conductance measurements, molecular-weight determinations, magnetic susceptibilities, and spectral studies viz., IR, 1H NMR, 19F NMR, and UV. The data support

  在本文中，简要介绍了苄叉肼甲酰胺或 -碳硫酰胺的钯 (II) 配合物的合成、立体化学和生化行为。双摩尔加成和取代产物已通过元素分析、电导测量、分子量测定、磁化率和光谱研究（即 IR、1H NMR、19F NMR 和 UV）进行表征。数据支持硫或氧和氮与钯的结合（X 是 O 或 S）类型的配合物。已经提出了方形平面几何。代表性的游离配体 () 及其各自的金属配合物在体外针对多种微生物进行了测试，以评估它们的抗菌性能，并在体内测试了它们的杀菌潜力。结果确实是积极的。
• Fahmi, Nighat; Singh, Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1997, vol. 36, # 9, p. 805 - 808
  作者：Fahmi, Nighat、Singh

  DOI：——

  日期：——
• Synthesis, Structure Elucidation and Biological Screening of Unsymmetrical Borole Complexes of Fluoroimines
  作者：Taruna Pandey、R. V. Singh

  DOI：10.1080/00945710009351804

  日期：2000.5.1

  Reactions of unsymmetrical borole complexes with fluoroimines having (NO)-O-boolean AND and (NS)-S-boolean AND donor systems have been undertaken. The fluoroimines were prepared by the condensation of 2-fluorobenzaldehyde or 2-fluoroacetophenone with semicarbazide hydrochloride or thiosemicarbazide. The resulting products are coloured non-electrolytic solids. An attempt has been made to probe the structures of the resulting complexes on the basis of micro analysis and spectral IR, H-1, C-13 and B-11 NMR studies.
• A New Series of Biologically Potent<i>cis</i>-Dioxomolybdenum(VI) Complexes of Fluoroimines
  作者：R. V. Singh、S. C. S. Jadon、Neeti Gupta

  DOI：10.1080/00945719708000225

  日期：1997.5

  The modern physico-chemical, spectroscopic and biochemical methods have proved an important tool to elucidate the constitution of reactive transition metal compounds. This article presents a brief account of the synthesis and stereochemistry of dioxomolybdenum(VI) complexes of fluoroimines. The mononuclear complexes were obtained by bimolar reactions of dioxobis(2,4-pentanediona-to-O,O')molybdenum(VI) with the monobasic bidentate fluoroimines containing N boolean AND S and N boolean AND O as the binding sites. Based on chemical analyses, IR and NMR spectra, conductance measurements and molecular weight determinations an octahedral geometry has been assigned to the newly synthesized products. The possibility of potential uses of these complexes as fungicides and bactericides, studied in vitro are also discussed.