2-(2'-hydroxy-4',5'-dimethoxyphenyl)-5-methoxy-[1,4]benzoquinone | 85969-39-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-(2'-hydroxy-4',5'-dimethoxyphenyl)-5-methoxy-[1,4]benzoquinone
• 英文别名: 2-(2-hydroxy-4,5-dimethoxyphenyl)-5-methoxy-1,4-benzoquinone；2-(2-Hydroxy-4,5-dimethoxyphenyl)-5-methoxy-1,4benzoquinone；2-(2-hydroxy-4,5-dimethoxyphenyl)-5-methoxycyclohexa-2,5-diene-1,4-dione
• CAS: 85969-39-7
• 化学式: C₁₅H₁₄O₆
• 分子量: 290.273
• InChiKey: WFERUMLVFPWORX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  82.1
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  2-(2'-hydroxy-4',5'-dimethoxyphenyl)-5-methoxy-[1,4]benzoquinone 在 氧气 、 四氯苯醌 作用下， 以 甲苯 为溶剂， 反应 120.0h， 以80%的产率得到3,7,8-trimethoxydibenzofuran-1,4-dione
  参考文献：
  名称：

  A Novel Construction of Dibenzofuran-1,4-diones by Oxidative Cyclization of Quinone-arenols

  摘要：

  A novel oxidative cyclization of quinone-arenols 5 leading to products 6 with a dibenzofuran-1,4-dione structure, which forms the core of several natural products, has been developed and applied to the synthesis of violet-quinone 4.

  DOI：

  10.1021/ol070951i
• 作为产物：
  描述：

  3,4-二甲氧基苯酚 在 sodium carbonate 、 tin(IV) oxide 、 potassium hexacyanoferrate(III) 作用下， 以 二氯甲烷 、 氯仿 、 水 为溶剂， 反应 1.08h， 生成 2-(2'-hydroxy-4',5'-dimethoxyphenyl)-5-methoxy-[1,4]benzoquinone
  参考文献：
  名称：

  A Novel Construction of Dibenzofuran-1,4-diones by Oxidative Cyclization of Quinone-arenols

  摘要：

  A novel oxidative cyclization of quinone-arenols 5 leading to products 6 with a dibenzofuran-1,4-dione structure, which forms the core of several natural products, has been developed and applied to the synthesis of violet-quinone 4.

  DOI：

  10.1021/ol070951i

文献信息

• Hewgill, Frank R.; Greca, Bart La; Legge, Frank, Journal of the Chemical Society. Perkin transactions I, 1983, # 1, p. 131 - 134
  作者：Hewgill, Frank R.、Greca, Bart La、Legge, Frank、Roga, Peter E.

  DOI：——

  日期：——
• A Novel Construction of Dibenzofuran-1,4-diones by Oxidative Cyclization of Quinone-arenols
  作者：Tetsuya Takeya、Hiromu Kondo、Tsuyoshi Otsuka、Kazuho Tomita、Iwao Okamoto、Osamu Tamura

  DOI：10.1021/ol070951i

  日期：2007.7.1

  A novel oxidative cyclization of quinone-arenols 5 leading to products 6 with a dibenzofuran-1,4-dione structure, which forms the core of several natural products, has been developed and applied to the synthesis of violet-quinone 4.