6-ethyl-1,2,3,4-tetrahydro-1,1,6-trimethylnaphthalene | 22824-28-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 6-ethyl-1,2,3,4-tetrahydro-1,1,6-trimethylnaphthalene
• 英文别名: 6-ethyl-1,1-dimethyl-1,2,3,4-tetrahydro-naphthalene；6-Aethyl-1,1-dimethyl-1,2,3,4-tetrahydro-naphthalin；1,1-dimethyl-6-ethyl-tetralin；2-Ethyl-5,5-dimethyl-5,6,7,8-tetrahydronaphthalin；6-Ethyl-1,1-dimethyl-1,2,3,4-tetrahydronaphthalene；7-ethyl-4,4-dimethyl-2,3-dihydro-1H-naphthalene
• CAS: 22824-28-8
• 化学式: C₁₄H₂₀
• 分子量: 188.313
• InChiKey: RDUDNIZSMNTPMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  6-ethyl-1,2,3,4-tetrahydro-1,1,6-trimethylnaphthalene 在 三氯化铝 、 硫酸 、 硝酸 作用下， 以 1,2-二氯乙烷 为溶剂， 生成 1-(3-ethyl-5,6,7,8-tetrahydro-8,8-dimethyl-4-nitro-2-naphthalenyl)ethanone
  参考文献：
  名称：

  Synthesis and herbicidal activity of substituted tetrahydronaphthalenes: I

  摘要：

  AbstractThis paper reports the synthesis and the biological activity of substituted 6‐alkyl‐1,2,3,4‐tetrahydro‐1,1‐dimethylnaphthalenes in which the substituents at the 5‐ and/or 7‐position are varied with a multitide of functional groups. These compounds exhibited pre‐emergent herbicidal activity which was a function of the electron‐withdrawing ability and the size of the groups substituted at the 5‐ and/or 7‐position. Nitro and/or nitrile groups at these positions tended to optimize activity.

  DOI：

  10.1002/ps.2780440206
• 作为产物：
  描述：

  在 硫酸 作用下， 生成 6-ethyl-1,2,3,4-tetrahydro-1,1,6-trimethylnaphthalene
  参考文献：
  名称：

  Polycyclic Musks. I. Acyl- and Dinitropolyalkyltetralin Derivatives

  摘要：

  DOI：

  10.1021/jo01044a022

文献信息

• THE CONSTITUTION OF THE METHYL IONONES^*
  作者：GEORGE WILLIAM POPE、MARSTON TAYLOR BOGERT

  DOI：10.1021/jo01226a010

  日期：1937.7
• Selective syntheses of substituted 6-alkyl-1,1-dimethyl-1,2,3,4-tetrahydronaphthalenes
  作者：John J. Parlow

  DOI：10.1016/s0040-4020(01)86337-7

  日期：1993.3

  Beta-ionone is cyclized to 1,1,6-trimethyl-1,2,3,4-tetrahydronaphthalene in 80-95% yield. Selective derivatization at the 5- and/or 7-positions of 6-alkyl-1,1-dimethyl-1,2,3,4-tetrahydronaphthalenes was achieved by nitration, acylation, and reduction.
• Polycyclic Musks. I. Acyl- and Dinitropolyalkyltetralin Derivatives
  作者：T. F. Wood、W. M. Easter、M. S. Carpenter、J. Angiolini

  DOI：10.1021/jo01044a022

  日期：1963.9
• Synthesis and herbicidal activity of substituted tetrahydronaphthalenes: I
  作者：John J. Parlow、Martin D. Mahoney

  DOI：10.1002/ps.2780440206

  日期：1995.6

  AbstractThis paper reports the synthesis and the biological activity of substituted 6‐alkyl‐1,2,3,4‐tetrahydro‐1,1‐dimethylnaphthalenes in which the substituents at the 5‐ and/or 7‐position are varied with a multitide of functional groups. These compounds exhibited pre‐emergent herbicidal activity which was a function of the electron‐withdrawing ability and the size of the groups substituted at the 5‐ and/or 7‐position. Nitro and/or nitrile groups at these positions tended to optimize activity.