2,6-di-(α-methylbenzyl)-4-methoxyphenol | 16790-04-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 2,6-di-(α-methylbenzyl)-4-methoxyphenol
• 英文别名: 4-Methoxy-2,6-bis(1-phenylethyl)phenol
• CAS: 16790-04-8
• 化学式: C₂₃H₂₄O₂
• 分子量: 332.442
• InChiKey: CDDPADFYDLJBIF-UHFFFAOYSA-N

物化性质

• 沸点：
  468.0±45.0 °C(Predicted)
• 密度：
  1.089±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  苯乙烯 、 4-甲氧基苯酚 在 oligomeric (4-methoxyphenoxy)alumoxane 作用下， 以94%的产率得到4-甲氧基-2-(1-苯乙基)-苯酚
  参考文献：
  名称：

  Alkylation of 4-methoxyphenol with styrene in the presence of alumoxane compounds

  摘要：

  The catalytic properties of alumoxane compounds in the alkylation of 4-methoxyphenol with styrene were studied. Structures and yields of alkylation products depend on the amount of catalyst, the phenol: olefin ratio, and the reaction time. Phenoxyalumoxanes are effective ortho-directing catalysts with respect to the hydroxy group. Under optimum conditions, 2-(alpha-methylbenzyl)-4-methoxyphenol and 2,5-di-(alpha-methylbenzyl)-4-methoxyphenol were obtained in 94% and 84-86% yields, respectively.

  DOI：

  10.1007/bf00698972

文献信息

• Alkylation of 4-methoxyphenol with styrene in the presence of alumoxane compounds
  作者：F. Kh. Inoyatov、R. Sh. Abubakirov、A. I. Mikaya、I. M. Khrapova、V. M. Perchenko、N. A. Plate

  DOI：10.1007/bf00698972

  日期：1993.5

  The catalytic properties of alumoxane compounds in the alkylation of 4-methoxyphenol with styrene were studied. Structures and yields of alkylation products depend on the amount of catalyst, the phenol: olefin ratio, and the reaction time. Phenoxyalumoxanes are effective ortho-directing catalysts with respect to the hydroxy group. Under optimum conditions, 2-(alpha-methylbenzyl)-4-methoxyphenol and 2,5-di-(alpha-methylbenzyl)-4-methoxyphenol were obtained in 94% and 84-86% yields, respectively.