2-(4-(二甲基氨基)苯基)乙酰肼 | 100133-14-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-(4-(二甲基氨基)苯基)乙酰肼
• 英文名称: (4-dimethylamino-phenyl)-acetic acid hydrazide
• 英文别名: (4-Dimethylamino-phenyl)-essigsaeure-hydrazid；2-(4-(Dimethylamino)phenyl)acetohydrazide；2-[4-(dimethylamino)phenyl]acetohydrazide
• CAS: 100133-14-0
• 化学式: C₁₀H₁₅N₃O
• mdl: MFCD08061561
• 分子量: 193.249
• InChiKey: NEZWLDSUVYAJED-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  58.4
• 氢给体数：
  2
• 氢受体数：
  3

安全信息

• 海关编码：
  2928000090

反应信息

• 作为反应物：
  描述：

  2-(4-(二甲基氨基)苯基)乙酰肼 在 硫酸 、 sodium nitrite 作用下， 生成 4-(dimethylamino)benzylisocyanate
  参考文献：
  名称：

  Monosized macroporous resins with epoxy groups and their structure and gel chromatography properties

  摘要：

  The monosized macroporous-polymer beads based on cross-linked poly(glycidyl methacrylate) have been synthesized by a new improving method-combining dispersion polymerization with swelling polymerization and polymeric solution porogens. The structure and gel chromatographic properties of the resins have been studied. The resins as matrix materials of various types of high performance liquid chromatography (HPLC) packings possess excellent separation properties.

  DOI：

  10.1007/bf02884676
• 作为产物：
  描述：

  4-dimethylaminobenzeneacetic acid methyl ester 在 一水合肼 作用下， 生成 2-(4-(二甲基氨基)苯基)乙酰肼
  参考文献：
  名称：

  Monosized macroporous resins with epoxy groups and their structure and gel chromatography properties

  摘要：

  The monosized macroporous-polymer beads based on cross-linked poly(glycidyl methacrylate) have been synthesized by a new improving method-combining dispersion polymerization with swelling polymerization and polymeric solution porogens. The structure and gel chromatographic properties of the resins have been studied. The resins as matrix materials of various types of high performance liquid chromatography (HPLC) packings possess excellent separation properties.

  DOI：

  10.1007/bf02884676

文献信息

• Substituted imidazo [1,5-a] [1,2,4] triazolo [4,3-d] [1,4] benzodiazepine derivatives
  申请人：——

  公开号：US20020103371A1

  公开（公告）日：2002-08-01

  The present invention is a compound of formula 1 The compound and derivatives or pharmaceutically acceptable salts thereof of the invention have a good affinity and selectivity to the GABA A &agr;5 receptor and are useful for the treatment of diseases related to this receptor.

  本发明是一种化合物，化学式为1。该发明的化合物及其衍生物或药学上可接受的盐具有良好的亲和力和选择性，对GABA A &agr;5受体具有作用，并可用于治疗与该受体相关的疾病。
• BENZODIAZEPINE DERIVATIVES AS GABA A RECEPTOR MODULATORS
  申请人：F. HOFFMANN-LA ROCHE AG

  公开号：EP1337535A2

  公开（公告）日：2003-08-27
• 2-(1,3,4-OXADIAZOL-2-YL)-7-OXO-1,6-DIAZABICYCLO[3.2.1 ]OCTANE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS
  申请人：WOCKHARDT LIMITED

  公开号：US20160297816A1

  公开（公告）日：2016-10-13

  Compounds of Formula (I), their preparation, and use in preventing or treating a bacterial infection are disclosed.
• NITROGEN CONTAINING COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS
  申请人：WOCKHARDT LIMITED

  公开号：US20160355516A1

  公开（公告）日：2016-12-08

  Compounds of Formula (I), their preparation, and use in preventing or treating a bacterial infection are disclosed. (I)
• US6743789B2
  申请人：——

  公开号：US6743789B2

  公开（公告）日：2004-06-01