2,2'-[(3-甲氧基丙基)亚氨基]二乙醇 | 76088-46-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 2,2'-[(3-甲氧基丙基)亚氨基]二乙醇
• 英文名称: 2,2'-<(3-Methoxypropyl)imino>diethanol
• 英文别名: 2,2'-[(3-methoxypropyl)imino]bisethanol；Methoxypropyl diethanolamine；2,2'-((3-Methoxypropyl)imino)bisethanol；2-[2-hydroxyethyl(3-methoxypropyl)amino]ethanol
• CAS: 76088-46-5
• 化学式: C₈H₁₉NO₃
• 分子量: 177.244
• InChiKey: WWFSTEZXAGUMLJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  12
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52.9
• 氢给体数：
  2
• 氢受体数：
  4

安全信息

• 海关编码：
  2922509090

反应信息

• 作为反应物：
  描述：

  2,2'-[(3-甲氧基丙基)亚氨基]二乙醇 在 盐酸 、 sodium hydroxide 、 氯化亚砜 、 N,N-二异丙基乙胺 、 苯磺酰氯 作用下， 以 乙醚 、 苯 为溶剂， 反应 8.75h， 生成 1-(3,4,5-Trimethoxyphenyl)-4-(3-methoxypropyl)piperazine
  参考文献：
  名称：

  杂环CNS药剂的类似物

  摘要：

  制备并测试了三十五种恶唑，噻唑，哌嗪和相关化合物，它们是已知的中枢神经系统药物的类似物。没有一种化合物比先导化合物更具活性。

  DOI：

  10.1002/jhet.5570170425
• 作为产物：
  描述：

  环氧乙烷 、 3-甲氧基丙胺 反应 17.5h， 以88%的产率得到2,2'-[(3-甲氧基丙基)亚氨基]二乙醇
  参考文献：
  名称：

  杂环CNS药剂的类似物

  摘要：

  制备并测试了三十五种恶唑，噻唑，哌嗪和相关化合物，它们是已知的中枢神经系统药物的类似物。没有一种化合物比先导化合物更具活性。

  DOI：

  10.1002/jhet.5570170425

文献信息

• Thiazolyl-Benzimidazoles
  申请人：Cai Jianping

  公开号：US20100160308A1

  公开（公告）日：2010-06-24

  The invention is directed to compounds of formula (1) and pharmaceutically acceptable salts thereof, methods for the preparation thereof, and methods of use thereof.

  这项发明涉及到式（1）的化合物及其药用可接受盐，其制备方法和使用方法。
• High Di(alkyl fatty ester) amines and quaternary ammonium compounds derived therefrom
  申请人：——

  公开号：US20020025915A1

  公开（公告）日：2002-02-28

  The present invention generally relates to a textile softening composition which comprises, as the softening agent, a quaternary ammonium salt which comprises a mixture of mono-, di- and tri-ester components, wherein the amount of diester quaternary is greater than about 50% by weight, and the amount of triester quaternary is less than about 25% by weight based on the total amount of quaternary ammonium salt. The invention also relates to a softening agent which comprises a high diester quaternary ammonium salt mixture comprising mono- and diester components derived for ether dialkanolamines. The invention also relates to processes for preparing said softening agents, and methods of use as a fabric softener and as a hair and skin conditioner.

  本发明涉及一种纺织品柔软剂组合物，其包括作为柔软剂的季铵盐，该季铵盐包括一种单酯、双酯和三酯成分的混合物，其中双酯季铵盐的含量大约占季铵盐总重量的50%以上，而三酯季铵盐的含量则小于季铵盐总重量的25%左右。本发明还涉及一种柔软剂，其包括高双酯季铵盐混合物，包括由醚二烷基胺衍生的单酯和双酯成分。本发明还涉及制备该柔软剂的方法，以及作为织物柔软剂和头发和皮肤调理剂的使用方法。
• High di(alkyl fatty ester) amines and quaternary ammonium compounds derived therefrom
  申请人：Akzo Nobel N.V.

  公开号：US06770608B2

  公开（公告）日：2004-08-03

  The present invention generally relates to a textile softening composition which comprises, as the softening agent, a quaternary ammonium salt which comprises a mixture of mono-, di- and tri-ester components, wherein the amount of diester quaternary is greater than about 50% by weight, and the amount of triester quaternary is less than about 25% by weight based on the total amount of quaternary ammonium salt. The invention also relates to a softening agent which comprises a high diester quaternary ammonium salt mixture comprising mono- and diester components derived for ether dialkanolamines. The invention also relates to processes for preparing said softening agents, and methods of use as a fabric softener and as a hair and skin conditioner.

  本发明涉及一种纺织品软化剂组合物，其软化剂为一种季铵盐，包括一种单酯、二酯和三酯组分的混合物，其中二酯季铵盐的重量百分比大于约50％，三酯季铵盐的重量百分比小于约25％，基于季铵盐的总量。本发明还涉及一种软化剂，其包括一种高二酯季铵盐混合物，包括从醚二烷醇胺衍生的单酯和二酯组分。本发明还涉及制备所述软化剂的方法，并作为织物柔软剂和头发和皮肤调理剂的使用方法。
• Quinoline derivatives and quinazoline derivatives
  申请人：Kubo Kazuo

  公开号：US20070027318A1

  公开（公告）日：2007-02-01

  An object of the present invention is to provide compounds which have antitumor activity and do not change cytomorphosis. Disclosed are compounds represented by formula (I) and a pharmaceutically acceptable salts and solvates thereof and pharmaceutical compositions comprising said compounds: wherein X and Z each independently represent CH or N; R 1 to R 3 represent H, substituted alkoxy, unsubstituted alkoxy or the like; R 4 represents H; R 5 to R 8 represent H, halogen, alkyl, alkoxy, alkylthio, nitro, or amino, provided that R 5 to R 8 do not simultaneously represent H; R 9 and R 10 represent H, alkyl, or alkylcarbonyl; and R 11 represents alkyl, alkenyl, alkynyl, or aralkyl.

  本发明的目的是提供具有抗肿瘤活性且不改变细胞形态的化合物。本发明揭示了由式（I）表示的化合物及其药学上可接受的盐和溶剂和包含所述化合物的制药组合物：其中X和Z各自独立地表示CH或N；R1至R3表示H，取代烷氧基，未取代烷氧基或类似物；R4表示H；R5至R8表示H，卤素，烷基，烷氧基，烷硫基，硝基或氨基，前提是R5至R8不同时表示H；R9和R10表示H，烷基或烷基羰基；R11表示烷基，烯基，炔基或芳基烷基。
• High di(alkyl fatty ester) quaternary ammonium compounds in fabric softening and personal care compositions
  申请人：Akzo Nobel N.V.

  公开号：US06323167B1

  公开（公告）日：2001-11-27

  The present invention generally relates to a textile softening composition which comprises, as the softening agent, a quaternary ammonium salt which comprises a mixture of mono-, di- and tri-ester components, wherein the amount of diester quaternary is greater than about 50% by weight, and the amount of triester quaternary is less than about 25% by weight based on the total amount of quaternary ammonium salt. The invention also relates to a softening agent which comprises a high diester quaternary ammonium salt mixture comprising mono- and diester components derived for ether dialkanolamines. The invention also relates to processes for preparing said softening agents, and methods of use as a fabric softener and as a hair and skin conditioner.

  本发明涉及一种纺织品柔软剂组合物，其包括作为柔软剂的季铵盐，该季铵盐包含一种单酯、二酯和三酯组分的混合物，其中二酯季铵盐的重量比大约大于50％，而三酯季铵盐的重量比约小于25％，基于总季铵盐的重量。本发明还涉及一种柔软剂，其包括高二酯季铵盐混合物，该混合物包括来源于醚二烷醇胺的单酯和二酯组分。本发明还涉及制备所述柔软剂的过程，以及作为织物柔软剂和头发和皮肤调理剂的使用方法。