tetrafluoro-1,4-phenylene diisocyanate | 16346-58-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tetrafluoro-1,4-phenylene diisocyanate
• 英文别名: 1,2,4,5-Tetrafluoro-3,6-diisocyanatobenzene
• CAS: 16346-58-0
• 化学式: C₈F₄N₂O₂
• 分子量: 232.094
• InChiKey: AHUMJSZHQHPXGN-UHFFFAOYSA-N

物化性质

• 熔点：
  67-68 °C
• 沸点：
  89-91 °C(Press: 5 Torr)
• 密度：
  1.56±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.9
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  2,4,5,6-四氟-1,3-苯二胺 在 盐酸 作用下， 以 丙酮 为溶剂， 反应 3.0h， 生成 tetrafluoro-1,4-phenylene diisocyanate
  参考文献：
  名称：

  取代类对苯二异氰酸酯的制备方法及非腈极性有机溶剂在其制备中的应用

  摘要：

  本发明属于精细化工技术领域，具体涉及一种取代类对苯二异氰酸酯的制备方法及非腈极性有机溶剂在其制备中的应用。本发明提供的非腈极性有机溶剂作为制备取代类对苯二异氰酸酯的反应溶剂，固体二胺(或其盐酸盐)在该溶剂体系中不断溶解，增加了二胺(或其盐酸盐)与光气的接触时间和接触面积，无需通过高温将固体二胺气化，简化了设备结构，降低了生产成本；该体系中已溶解的二胺(或其盐酸盐)和光气的停留时间分布大致相等，过程可控。本发明提供的取代类对苯二异氰酸酯的制备方法采用非腈极性有机溶剂体系，避免了大量废水的产生，以减少对环境的污染，同时还减少了取代类对苯二胺盐酸盐在过滤操作时损失，提高了收率。

  公开号：

  CN110183356A

文献信息

• Medical Adhesive
  申请人：Yoshimura Tetsuji

  公开号：US20070282093A1

  公开（公告）日：2007-12-06

  The present invention has its object to provide a medical adhesive excellent in safety, reactivity (curing rate) and duration of adhesive strength. A medical adhesive of the present invention comprises a hydrophilic urethane prepolymer (UP) obtained by reacting a fluorine-containing nonaromatic polyisocyanate component (A) and a polyol component (B) having a hydrophilic polyol (B 1 ) as the essential component, and a phenolic radical scavenger (PRS). The content of (PRS) is preferably 0.01 to 3% by weight based on the weight of (UP). The content of oxyethylene groups in (B) is preferably 30 to 100% by weight based on the weight of the oxyalkylene groups in (B). Preferably, (B) is a mixture of a random copolymer obtained by addition of ethylene oxide and propylene oxide to diols and polypropylene glycol. The content of isocyanate groups in the medical adhesive is 1 to 10% by weight based on the weight of (UP). The medical adhesive of the present invention is suitable for bonding body tissues, such as lung, artery and heart in particular.

  本发明的目的是提供一种在安全性、反应性（固化速率）和粘接强度持续时间方面具有优异性能的医用粘合剂。本发明的医用粘合剂包括通过反应含氟非芳香族多异氰酸酯组分（A）和具有亲水性多元醇（B1）作为基本组分的多元醇组分（B）获得的亲水性聚氨酯预聚物（UP）和酚类自由基清除剂（PRS）。根据（UP）的重量，（PRS）的含量优选为0.01至3重量％。根据（B）中氧乙烯基团的重量，氧乙烯基团的含量优选为30至100重量％。优选地，（B）是通过将环氧丙烷和丙烯酸酯添加到双醇和聚丙烯醇中获得的随机共聚物的混合物。医用粘合剂中异氰酸酯基团的含量根据（UP）的重量为1至10重量％。本发明的医用粘合剂特别适用于粘接肺、动脉和心脏等体内组织。
• Ophthalmic device comprising a polymer of a telechelic perfluoropolyether
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0084406A1

  公开（公告）日：1983-07-27

  Ophthalmic devices, such as contact lenses, of polymers of telechelic perfluorinated polyether monomers, and compositions for making such devices are disclosed. The devices possess improved oxygen permeability.

  本发明公开了由远志全氟聚醚单体聚合物制成的眼科设备（如隐形眼镜）以及用于制造此类设备的组合物。 这些设备具有更好的透氧性。
• Process for preparing heterocyclic copolymers
  申请人：Tonen Chemical Corporation

  公开号：EP0323219A2

  公开（公告）日：1989-07-05

  Process for preparing a heterocyclic copolymer having recurring units [A] and [B] obtained by hydrolizing reaction products of specific diisocyanate compounds with tolidine diisocyanate and hydrogen cyanide. The copolymers are excellent in mechanical strength, heat resistance and solvent resistance.

  一种杂环共聚物的制备方法，该共聚物具有通过将特定二异氰酸酯化合物与托利丁二异氰酸酯和氰化氢的反应产物水解而获得的重复单元[A]和[B]。 这种共聚物具有优异的机械强度、耐热性和耐溶剂性。
• Fluorinated polyurethanes containing rubber-like polyoxyperfluoroalkylene blocks and rigid blocks
  申请人：AUSIMONT S.p.A.

  公开号：EP0359272A2

  公开（公告）日：1990-03-21

  Polyurethanes comprising rubber-like polyoxyperfluoroalkylene blocks and rigid segments derived from short-chain aliphatic diols and/or aliphatic or aromatic diamines and from (cyclo)aliphatic or aromatic diisocyanates, wherein the number of rigid segments is equal to or higher than the number of rubber-like blocks are described. Said polyurethanes are characterized by a glass transition temperature lower than -80°C, a tensile strength higher that 30 kg/cm² and a hardness of from 50 Shore A to 75 Shore D and show good thermoforming characteristics.

  所述聚氨酯由橡胶状聚全氟烷烃嵌段和刚性段组成，刚性段来源于短链脂肪族二元醇和/或脂肪族或芳香族二元胺以及（环）脂肪族或芳香族二异氰酸酯，其中刚性段的数量等于或高于橡胶状嵌段的数量。这些聚氨酯的特点是玻璃化转变温度低于 -80°C，拉伸强度高于 30 kg/cm²，硬度介于 50 Shore A 到 75 Shore D 之间，并具有良好的热成型特性。
• Fluorinated polyurethanes containing polyoxyperfluoroalkylene blocks
  申请人：AUSIMONT S.r.l.

  公开号：EP0359273A2

  公开（公告）日：1990-03-21

  Polyurethanes comprising rubber-like polyoxyperfluoroalkylene blocks and rigid segments derived from low molecular weight compounds and from (cyclo)aliphatic or aromatic diisocyanates, wherein the number of rigid segments is higher than the number of rubber-like blocks, are described. Said polyurethanes are characterized by a glass transition temperature lower than -80°C, a tensile strength higher than 30 kg/cm² and a hardness of from 50 Shore A to 75 Shore D, and show good thermoforming characteristics.

  描述了由橡胶状聚全氟烷烃嵌段和刚性段组成的聚氨酯，刚性段来自低分子量化合物和（环）脂肪族或芳香族二异氰酸酯，其中刚性段的数量高于橡胶状嵌段的数量。这些聚氨酯的特点是玻璃化转变温度低于 -80°C，拉伸强度高于 30 kg/cm²，硬度从 50 Shore A 到 75 Shore D，并具有良好的热成型特性。