1-methyl-3-(2-methoxyethyl)-2-imidazolidinone | 131679-66-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 1-methyl-3-(2-methoxyethyl)-2-imidazolidinone
• 英文别名: 1-(2-methoxyethyl)-3-methylimidazolidin-2-one
• CAS: 131679-66-8
• 化学式: C₇H₁₄N₂O₂
• 分子量: 158.2
• InChiKey: QHHCHYAXPBQVJX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.6
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  32.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-methyl-3-(2-methoxyethyl)-2-imidazolidinone 、 4-2-胺苯基吗啉 、 三氯氧磷 、 富马酸 以 苯 、 甲醇 为溶剂， 反应 30.0h， 以gave an oil a portion of which (1.8 g)的产率得到4-((2-[1-Methyl-3-(2-methoxyethyl)-2-imidazolidinylideneamino]phenyl))morpholine monofumarate
  参考文献：
  名称：

  Phenylamidine and phenylguanidine derivatives and their use as

  摘要：

  式I的化合物及其盐，其中n=0或1，R1和R2均为脂肪族或环烷基，或NR1R2为可选择取代的杂环环，R3为烷基，环烷基或可选择取代的氨基，R5为脂肪基，R6为H，可选择取代的脂肪基或环烷基，或R3和R5与它们所连接的氮和碳原子共同形成可选择取代的杂环环，或R5和R6与它们所连接的氮共同形成可选择取代的杂环环，或R7为可选择取代的烷基，烷氧基，烷基硫醚基，烷基磺酰基，烷氧羰基，三氟甲基或氰基，具有降糖剂的用途。

  公开号：

  US05223498A1
• 作为产物：
  描述：

  1-(2-羟乙基)-2-咪唑啉酮 、 碘甲烷 以 N-甲基乙酰胺 、 paraffin oil 为溶剂， 生成 1-methyl-3-(2-methoxyethyl)-2-imidazolidinone
  参考文献：
  名称：

  Phenylamidine and phenylguanidine derivatives and their use as

  摘要：

  公式I的化合物及其盐，其中n=0或1，R.sub.1和R.sub.2分别为脂肪族或环烷基，或NR.sub.1 R.sub.2是一个可选择取代的杂环环，R.sub.3是烷基，环烷基或可选择取代的氨基，R.sub.5是脂肪基，R.sub.6是H，可选择取代的脂肪基或环烷基，或R.sub.3和R.sub.5与它们连接的氮和碳原子形成一个可选择取代的杂环环，或R.sub.5和R.sub.6与它们连接的氮形成一个可选择取代的杂环环，R.sub.7是可选择取代的烷基，烷氧基，烷基硫醇，烷基磺醇，烷基磺酰基，烷氧羰基，三氟甲基或氰基，具有降血糖剂的用途。

  公开号：

  US05223498A1

文献信息

• Arylamine-substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists
  申请人：Connolly Joseph Terrence

  公开号：US20070265446A1

  公开（公告）日：2007-11-15

  Compounds represented by Formula I: which are useful as are alpha-1A/B adrenoceptor antagonists, to methods of treating conditions associated with the activity of alpha-1A/B adrenoceptors, and to methods of making said compounds, wherein Ar, Z, R, R′, R 5 and R 10 are as defined herein.

  公式I所代表的化合物：它们可用作α-1A/B肾上腺素受体拮抗剂，用于治疗与α-1A/B肾上腺素受体活性相关的疾病的方法，以及制备该化合物的方法，其中Ar、Z、R、R′、R5和R10如本文所定义。
• Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them
  申请人：The Boots Company PLC

  公开号：EP0385038A1

  公开（公告）日：1990-09-05

  Compounds of formula I and their salts in which n = 0 or 1, R1 and R2 are each aliphatic or cycloalkyl or NR1 R2 is an optionally substituted heterocyclic ring, R3 is alkyl, cycloalkyl or optionally substituted amino, R5 is an aliphatic group, R6 is H, an optionally substituted aliphatic group or a cycloalkyl group, or R3 and R5 together with the nitrogen and carbon atoms to which they are attached form an optionally substituted heterocyclic ring or R5 and R6 together with the nitrogen to which they are attached form a heterocyclic ring optionally substituted by alkyl and R7 is optionally substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, alkoxycarbonyl, trifluoromethyl or cyano have utility as hypoglycaemic agents.

  式 I 的化合物及其盐类 及其盐类，其中 n = 0 或 1，R1 和 R2 各为脂肪族或环烷基或 NR1 R2 为任选取代的杂环，R3 为烷基、环烷基或任选取代的氨基，R5 为脂肪族基团，R6 为 H、任选取代的脂肪族基团或环烷基基团、或 R3 和 R5 与它们所连接的氮原子和碳原子一起形成一个任选取代的杂环，或 R5 和 R6 与它们所连接的氮原子一起形成一个任选被烷基取代的杂环，R7 是任选取代的烷基、烷氧基、烷硫基、烷基亚砜基、烷基磺酰基、烷氧基羰基、三氟甲基或氰基。
• Tire tread composition
  申请人：BRIDGESTONE CORPORATION

  公开号：EP0572792A1

  公开（公告）日：1993-12-08

  The present invention relates to a composition comprising an elastomeric polymer functionally modified by a terminal group, and carbon black particles dispersed therein, with at least 10 percent by weight of said carbon black being oxidized carbon black.

  本发明涉及一种组合物，该组合物包含一种经末端基团功能改性的弹性聚合物，以及分散在其中的炭黑颗粒，按重量计，所述炭黑中至少有 10% 为氧化炭黑。
• A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer
  申请人：BRIDGESTONE CORPORATION

  公开号：EP0609010A2

  公开（公告）日：1994-08-03

  A process for producing a diolefin polymer or copolymer, comprising the steps of polymerizing 55-100 wt% of a conjugated diolefin with 0-45 wt% of an aromatic vinyl compound as monomers in a hydrocarbon as a solvent, by using initiators: a reaction product [a1] between at least one secondary amine compound (A) and an organic lithium compound and/or a lithium amide compound [a2] of the at least one secondary amine compound (A) as well as a reaction product [b1] between at least one alcohol (B) and an organic lithium compound and/or a lithium alkoxide compound of the at least one alcohol (B). A rubber composition containing not less than 30 wt% of such a diolefin polymer or copolymer with respect to an entire rubber component is also disclosed. This rubber composition exhibits excellent abrasion resistance, high tensile strength, steering stability and low rolling resistance, and is suitable for tires, particularly, as treads of low fuel consumption tires.

  一种生产二烯烃聚合物或共聚物的工艺，包括以下步骤：以烃类为溶剂，使用引发剂使 55-100 wt%的共轭二烯烃与 0-45 wt%的芳香乙烯基化合物作为单体聚合：至少一种仲胺化合物（A）与有机锂化合物和/或至少一种仲胺化合物（A）的锂酰胺化合物[a2]之间的反应产物[a1]，以及至少一种醇（B）与有机锂化合物和/或至少一种醇（B）的锂烷氧基化合物之间的反应产物[b1]。此外，还公开了一种橡胶组合物，其中二烯烃聚合物或共聚物的含量不低于整个橡胶组分的 30%。这种橡胶组合物具有优异的耐磨性、高拉伸强度、转向稳定性和低滚动阻力，适用于轮胎，特别是低油耗轮胎的胎面。
• POLYVINYL ALCOHOL RESIN COMPOSITION AND MULTILAYER PACKAGES
  申请人：Kuraray Co., Ltd.

  公开号：EP1316582A1

  公开（公告）日：2003-06-04

  The present invention provides a resin composition having an oxygen scavenging function. The resin composition comprises 70 to 99.9 wt% of a polyvinyl alcohol resin (A) and 0.1 to 30 wt% of a thermoplastic resin (B) other than the polyvinyl alcohol resin (A), wherein the thermoplastic resin (B) has a carbon-carbon double bond and a functional group including a hetero atom, and an oxygen absorption rate of the resin composition is 0.001 ml/m2 • day or more.

  本发明提供了一种具有氧清除功能的树脂组合物。该树脂组合物包括 70 至 99.9 wt%的聚乙烯醇树脂（A）和 0.1 至 30 wt%的除聚乙烯醇树脂（A）之外的热塑性树脂（B），其中热塑性树脂（B）具有碳碳双键和包括杂原子的官能团，该树脂组合物的吸氧率为 0.001 ml/m2 - 天或以上。