2-苯基戊-4-烯-1,2-二醇 | 89358-17-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-苯基戊-4-烯-1,2-二醇
• 英文名称: 2-phenylpent-4-ene-1,2-diol
• CAS: 89358-17-8
• 化学式: C₁₁H₁₄O₂
• 分子量: 178.231
• InChiKey: YESNHEUZAHZGNW-UHFFFAOYSA-N

物化性质

• 沸点：
  80 °C(Press: 3 Torr)
• 密度：
  1.095±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-苯基戊-4-烯-1,2-二醇 在 吡啶 、 4-二甲氨基吡啶 、 lithium aluminium tetrahydride 作用下， 以 乙醚 为溶剂， 生成 (S)-(-)-2-phenyl-4-penten-2-ol
  参考文献：
  名称：

  Asymmetric Synthesis of the Both Enantiomers of Tertiary Aryl Homoallyl Alcohols and Diols by Diastereoselective Addition of Allyltrimethylsilane to Chiral α-Keto Imides

  摘要：

  通过四氯化钛促进烯丙基三甲基硅烷非对映选择性加成到手性 α-酮酰亚胺上，以高对映体过量 (91–>98% e.e.) 获得高烯丙醇和 -二醇的两种对映体。

  DOI：

  10.1246/cl.1987.341
• 作为产物：
  描述：

  1-chloromethyl-1-phenylbut-3-en-1-ol 在 正丁基锂 、 氧气 、 naphthalen-1-yl-lithium 作用下， 生成 2-苯基戊-4-烯-1,2-二醇
  参考文献：
  名称：

  Barluenga, Jose; Florez, Josefa; Yus, Miguel, Journal of the Chemical Society. Perkin transactions I, 1983, # 12, p. 3019 - 3026

  摘要：

  DOI：

文献信息

• Lipase AKG mediated resolutions of α,α-disubstituted 1,2-diols in organic solvents; remarkably high regio- and enantio-selectivity
  作者：Robert P. Hof、Richard M. Kellogg

  DOI：10.1039/p19960002051

  日期：——

  Diols 1, which contain adjacent tertiary and primary hydroxy groups, can be selectively mono-acylated at the primary hydroxy group by many lipases in organic solvents, Since the reaction does not take place at the chiral tertiary centre itself, observed enantioselectivities are usually low. Only the combination of one lipase, lipase AKG (Amano, Pseudomonas sp.), with selected substrates gives high enantioselectivities (E 20 to > 200), Also, the solvent and acyl donor employed influences the outcome, On the basis of the results of Lipase AKG towards substrates 1 an active site model for this specific lipase has been developed, which can account for the results obtained, Fu!! experimental details on the synthesis of diols 1 and enzymatic preparation of acetates 2 are given, Also, the absolute stereochemistry of the enzymatically prepared diols 1 has been established by independent synthesis from (R)-mandelic acid.
• Lipase catalyzed résolutions of some α,α-disubstituted 1,2-diols in organic solvents; near absolute regio and chiral recognition.
  作者：Robert P. Hof、Richard M. Kellogg

  DOI：10.1016/0957-4166(94)80019-7

  日期：1994.4

  Several racemic 1,2-diols bearing a tertiary benzylic alcohol stereogenic center can be esterified regioselectively by vinyl acetate using lipases and esterases in organic media. With the correct choice of enzyme and if the non-phenyl substituent at the tertiary center is unsaturated, E values of > 250 can be achieved.
• BARLUENGA, J.;FOREZ, J.;YUS, M., J. CHEM. SOC. PERKIN TRANS., 1983, N 12, 3019-3026
  作者：BARLUENGA, J.、FOREZ, J.、YUS, M.

  DOI：——

  日期：——
• KUPCHIK, I. P.;KORYAK, EH. B.;GEVAZA, YU. I.;STANINETS, V. I., YKP. XIM. ZH., 54,(1988) N 11, S. 1180-1183
  作者：KUPCHIK, I. P.、KORYAK, EH. B.、GEVAZA, YU. I.、STANINETS, V. I.

  DOI：——

  日期：——
• Texturing and cleaning agent for the surface treatment of wafers and use thereof
  申请人：Mayer Kuno

  公开号：US20110092074A1

  公开（公告）日：2011-04-21

  A liquid agent for the surface treatment of monocrystalline wafers, which contains an alkaline etching agent and also at least one low-volatile organic compound. Systems of this type can be used both for the cleaning, damage etch and texturing of wafer surfaces in a single etching step and exclusively for the texturing of silicon wafers with different surface quality, whether it now be wire-sawn wafers with high surface damage or chemically polished surfaces with minimum damage density.