(meso-tetra(4-methoxycarbonylphenyl)porphyrinato)platinum(II) | 159564-92-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (meso-tetra(4-methoxycarbonylphenyl)porphyrinato)platinum(II)
• 英文别名: platinum(II) tetrakis(4-methoxycarbonylphenyl)porphyrinate；platinum(II) tetrakis(4-methoxycarbonylphenyl)porphyrin；PtTMCPP
• CAS: 159564-92-8
• 化学式: C₅₂H₃₆N₄O₈Pt
• 分子量: 1039.96
• InChiKey: WVCGDUIJOVIADO-NHZJRHMYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
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• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  (meso-tetra(4-methoxycarbonylphenyl)porphyrinato)platinum(II) 在 sodium hydroxide 作用下， 以 乙醇 、 水 为溶剂， 以83.6%的产率得到Pt(II) meso-tetra(4-carboxyphenyl)porphine sodium salt
  参考文献：
  名称：

  双发射铂（II）金属氧传感器对缺氧的成像和引导的化学疗法具有敏感的氧响应。

  摘要：

  体内缺氧的影像有助于准确诊断癌症并评估治疗效果。具有体内氧气响应性红色磷光和稳定荧光的Pt II金属绷带据报道缺氧显像和化疗。通过杂化定向自组装将治疗剂和诊断探针整合到金属链中。通过将金属乳剂包封在纳米颗粒中的纳米配方大大增强了其在生理环境中的稳定性，从而使生物医学应用可行。除了缺氧时红色磷光增强外，红色和蓝色发射之间的比率（仅随细胞内氧气水平而变化）为缺氧成像和检测提供了更精确的标准。此外，体内研究表明，载有金属的纳米颗粒可作为治疗肿瘤低氧影像和化学疗法的治疗剂的潜在应用。

  DOI：

  10.1002/anie.202009442
• 作为产物：
  描述：

  对甲酰基苯甲酸甲酯 以 丙酸 、 苯甲腈 为溶剂， 反应 14.0h， 生成 (meso-tetra(4-methoxycarbonylphenyl)porphyrinato)platinum(II)
  参考文献：
  名称：

  一种羧基官能化的铂卟啉材料及其制备方法和应用

  摘要：

  本发明涉及催化材料技术领域，公开了一种羧基官能化的铂卟啉材料及其制备方法和应用。该材料是以取代甲酰基苯甲酸甲酯和吡咯反应得到5,10,15,20‑(取代甲酸甲酯苯基)卟啉，5,10,15,20‑(取代甲酸甲酯苯基)卟啉与PtCl2反应得到5,10,15,20‑(取代甲酸甲酯苯基)铂卟啉，再经脱羧反应得到5,10,15,20‑(取代羧基苯基)铂卟啉。与现有技术相比，本发明制备的5,10,15,20‑(取代羧基苯基)铂卟啉具有优良地吸收光、激发自由电子和光催化性能，可以在温和条件下高转化率催化转化CO2，并高选择性生产CO。

  公开号：

  CN113583010A

文献信息

• Phosphorescent Oxygen Sensor with Dendritic Protection and Two-Photon Absorbing Antenna
  作者：Raymond P. Briñas、Thomas Troxler、Robin M. Hochstrasser、Sergei A. Vinogradov

  DOI：10.1021/ja052947c

  日期：2005.8.24

  Imaging oxygen in 3D with submicron spatial resolution can be made possible by combining phosphorescence quenching technique with multiphoton laser scanning microscopy. Because Pt and Pd porphyrin-based phosphorescent dyes, traditionally used as phosphors in biological oxygen measurements, exhibit extremely low two-photon absorption (2PA) cross-sections, we designed a nanosensor for oxygen, in which a 2P absorbing antenna is coupled to a metalloporphyrin core via intramolecular energy transfer (ET) with the purpose of amplifying the 2PA induced phosphorescence of the metalloporphyrin. The central component of the device is a polyfunctionalized Pt porphyrin, whose triplet state emission at ambient temperatures is strong, occurs in the near infrared and is sensitive to O-2. The 2PA chromophores are chosen in such a way that their absorption is maximal in the near infrared (NIR) window of tissue (e.g., 700-900 nm), while their fluorescence is overlapped with the absorption band(s) of the core metalloporphyrin, ensuring an efficient antenna-core resonance ET. The metalloporphyrin-antenna construct is embedded inside the protecting dendritic jacket, which isolates the core from interactions with biological macromolecules, controls diffusion of oxygen and makes the entire sensor water-soluble. Several Pt porphyrin-cournarin based sensors were synthesized and their photophyics studied to evaluate the proposed design.
• Porphyrin-Based Metal–Organic Frameworks for Efficient Photocatalytic H₂ Production under Visible-Light Irradiation
  作者：Chenxiang Lin、Chaozheng Han、Haijiao Zhang、Lei Gong、Ying Gao、Hailong Wang、Yongzhong Bian、Renjie Li、Jianzhuang Jiang

  DOI：10.1021/acs.inorgchem.1c00041

  日期：2021.3.15
• 10.1007/s11171-008-2015-x
  作者：Rumyantseva、Ivanovskaya、Konovalenko、Tsukanov、Mironov、Osin

  DOI：10.1007/s11171-008-2015-x

  日期：——
• Vasil'ev; Borisov; Chubarova, Russian Journal of Inorganic Chemistry, 2003, vol. 48, # 3, p. 385 - 390
  作者：Vasil'ev、Borisov、Chubarova、Rumyantseva

  DOI：——

  日期：——
• Platinum porphyrinsV. Multinuclear NMR of some platinum(IV) porphyrins
  作者：Lionel R. Milgrom、Richard J. Zuurbier、J.Malcolm Gascoyne、David Thompsett、Brian C. Moore

  DOI：10.1016/s0277-5387(00)86593-6

  日期：1994.1

  Multinuclear (i.e. H-1 C-13 and Pt-195) NMR spectra of six platinum(IV) porphyrin complexes are reported. Compared with their platinum (II) porphyrin precursors, alphacarbon (C-alpha) resonances are shifted further upfield, H-1-Pt-195 and C-13-(195)pt coupling constants are significantly reduced, Pt-195 resonances are shifted further downfield (their relative positions being more strongly affected by macrocyclic substitution) and (195)pt peaks are appreciably narrowed. These differences are rationalized in terms of oxidation leading to reduced coupling of (195)pt to the N-14 C-13 and H-1 atoms of the porphyrin, a slight increase in d-pi(*) back-bonding and its modulation by porphyrin substituents.