1,3,5-triphenyl-1,1,3,5,5-pentahydroxytrisiloxane | 18537-00-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,3,5-triphenyl-1,1,3,5,5-pentahydroxytrisiloxane
• 英文别名: triphenyl-trisiloxane-1,1,3,5,5-pentaol；Triphenyl-trisiloxan-1,1,3,5,5-pentaol；bis[[dihydroxy(phenyl)silyl]oxy]-hydroxy-phenylsilane
• CAS: 18537-00-3
• 化学式: C₁₈H₂₀O₇Si₃
• 分子量: 432.609
• InChiKey: FWGPPVDPYMTBNL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.48
• 重原子数：
  28
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  120
• 氢给体数：
  5
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  苯基三氯硅烷 在 水 作用下， 生成 1,3,5-triphenyl-1,1,3,5,5-pentahydroxytrisiloxane
  参考文献：
  名称：

  Andrianow; Shdanow, Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1954, p. 1033,1036;engl.Ausg.S.901,903

  摘要：

  DOI：

文献信息

• Acid-Catalyzed Condensation Reaction of Phenylsilanetriol: Unexpected Formation of <i>cis,trans</i>-1,3,5-Trihydroxy-1,3,5-triphenylcyclotrisiloxane as the Main Product and Its Isolation
  作者：Fujio Yagihashi、Masayasu Igarashi、Yumiko Nakajima、Wataru Ando、Kazuhiko Sato、Yoshiyuki Yumoto、Chinami Matsui、Shigeru Shimada

  DOI：10.1021/om500691c

  日期：2014.11.24

  characterized by spectroscopic methods and single-crystal X-ray diffraction. This compound was believed to be highly unstable and only exist as a transient species in low concentration during the condensation reaction of phenylsilanetriol or its precursors. The isolated pure cyclotrisiloxane is, however, surprisingly stable even in acidic solution and partially isomerizes to the cis,cis isomer.

  顺式，反式-1,3,5-三羟基-1,3,5-三苯基环三硅氧烷已成功分离，并通过光谱法和单晶X射线衍射进行了充分表征。该化合物被认为是高度不稳定的，并且仅在苯基硅烷三醇或其前体的缩合反应期间以低浓度作为过渡物种存在。然而，即使在酸性溶液中，分离的纯的环三硅氧烷也出乎意料地稳定并且部分异构化为顺式，顺式异构体。
• Synthesis of colloidal Janus nanoparticles by asymmetric capping of mesoporous silica with phenylsilsesquioxane
  作者：Hiroto Ujiie、Atsushi Shimojima、Kazuyuki Kuroda

  DOI：10.1039/c4cc10064f

  日期：——

  Janus-type mesoporous silica nanoparticles asymmetrically capped with non-porous phenylsilsesquioxane have been prepared by simply adding phenyltriethoxysilane to an aqueous dispersion of mesostructured silica–surfactant composite nanoparticles.

  直接给您翻译结果：

  通过将苯三乙氧基硅烷简单地加入介孔硅-表面活性剂复合纳米粒子的水分散液中，制备了非均质封顶非多孔苯基硅氧烷的Janus型介孔二氧化硅纳米粒子。

• The enzymatic cleavage of Si–O bonds: A kinetic analysis of the biocatalyzed hydrolysis of phenyltrimethoxysilane
  作者：Mark B. Frampton、Razvan Simionescu、Travis Dudding、Paul M. Zelisko

  DOI：10.1016/j.molcatb.2010.04.002

  日期：2010.9

  Previously we reported the ability of trypsin to mediate the cross-linking of alkoxysily-functionalized silicone polymers. Although enzymes and silicon-containing compounds are not necessarily incompatible species, the exact mechanism of how enzymes process silicon substrates is not fully understood. The focus of this current work was to examine the reaction kinetics associated with the processing of an alkoxysilane substrate by enzymes using Si-29 NMR so as to gain a greater insight into the actual reaction mechanism, especially those involving more complex silicone systems. A series of time course Si-29 NMR experiments using D2O revealed that the trypsin-mediated hydrolysis of a single alkoxy moiety in water is a pseudo-first order reaction. The relative effect of the enzyme was determined to be beta = 3.549 while the relative effect of water was gamma = 3.325. Prolonged contact with phenyltrimethoxysilane was not sufficiently deleterious to the enzyme and did not induce the complete and irreversible denaturation of trypsin. Computational evidence suggests that while in the active site of the enzyme, serine addition to silicon to forms a pentacoordinate species and is favoured over histidine addition. (C) 2010 Elsevier B.V. All rights reserved.