1,1,3,3-tetra(methylamine)propane | 771573-60-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,1,3,3-tetra(methylamine)propane
• 英文别名: 2,4-Bis(aminomethyl)pentane-1,5-diamine
• CAS: 771573-60-5
• 化学式: C₇H₂₀N₄
• mdl: MFCD06213721
• 分子量: 160.263
• InChiKey: XTAVXHOQWDONFZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.7
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  104
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,1,3,3-tetra(methylamine)propane 在 三乙基铝 作用下， 以 乙醇 、 甲苯 为溶剂， 反应 32.0h， 生成
  参考文献：
  名称：

  Highly stereoselective bimetallic complexes for lactide and ε-caprolactone polymerization

  摘要：

  我们合成了一系列含有双金属配体和两个铝中心的希夫碱化合物，并通过 1H、13C NMR 和元素分析对其进行了表征。这些化合物可成功用作 rac-lactide 和 ε-caprolactone 聚合反应的催化剂。用这些化合物制备的聚乳酸（PLA）具有很高的同素异形富集度（Pm = 0.97）。与中心金属离子配位的配体的性质和立体阻碍显著影响了聚合物的特性。动力学研究表明，这些化合物和内酯/己内酯单体的聚合均为一阶聚合。所有聚合反应都是活的，分子量控制良好，摩尔质量分布相对较窄。

  DOI：

  10.1039/c4ra11126e
• 作为产物：
  描述：

  四甲基丙烷-1,1,3,3-四羧酸酯 在 氨 、 diborane(6) 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 25.0h， 生成 1,1,3,3-tetra(methylamine)propane
  参考文献：
  名称：

  Highly stereoselective bimetallic complexes for lactide and ε-caprolactone polymerization

  摘要：

  我们合成了一系列含有双金属配体和两个铝中心的希夫碱化合物，并通过 1H、13C NMR 和元素分析对其进行了表征。这些化合物可成功用作 rac-lactide 和 ε-caprolactone 聚合反应的催化剂。用这些化合物制备的聚乳酸（PLA）具有很高的同素异形富集度（Pm = 0.97）。与中心金属离子配位的配体的性质和立体阻碍显著影响了聚合物的特性。动力学研究表明，这些化合物和内酯/己内酯单体的聚合均为一阶聚合。所有聚合反应都是活的，分子量控制良好，摩尔质量分布相对较窄。

  DOI：

  10.1039/c4ra11126e

文献信息

• Synthesis and characterization of binuclear Co(II) complexes with bis(salen-type) ligands
  作者：Minna T. Räisänen、Heikki Korpi、Markku R. Sundberg、Alexander Savin、Markku Leskelä、Timo Repo

  DOI：10.1016/j.ica.2012.08.007

  日期：2013.1

  Two new, bridged bis(salen-type) ligand precursors, 1,1,3,3-tetrakis(salicylidene-3-iminopropyl)butylenediamine (I) and 1,1,3,3-tetra(salicylideneiminomethyl)propane (IV), were prepared by Schiff base condensation of salicylaldehyde with appropriate tetraamines. Corresponding binuclear Co(II) complexes 1 and 2 were obtained with moderate yields and the complexes were characterized in detail. Structural optimizations of the complexes were carried out at the B3LYP/6-311G/* level of theory. Dioxygen coordination abilities of 1 and 2 were studied experimentally by UV-Vis spectroscopy and compared with traditional N,N'-ethylenebis(salicylideniminato)Co(II), Co(salen) (3). In addition, catalytic activities of 1 and 2 in comparison with various mononuclear salen-type Co complexes (3-7) were studied in the oxidation of 3,4-dimethoxybenzyl alcohol (veratryl alcohol) in alkaline aqueous solutions. (C) 2012 Elsevier B. V. All rights reserved.
• Arene Ruthenium (ll) Compounds And Their Use In Cancer Therapy
  申请人：Habtemariam Abraha

  公开号：US20080096846A1

  公开（公告）日：2008-04-24

  A ruthenium (II) compound of formula (I): or a solvate on prodrug thereof, wherein: R 1 , R 1 , R 3 , R 4 , R 5 and R 6 are independently selected from H, C 1-7 alkyl, C 5-20 aryl, C 3-20 heterocyclyl, halo, ester, amido, acyl, sulfo, sulfonamido, ether, thioether, azo, amino, or R 1 and R 2 together with the ring to which they are attached form a saturated or unsaturated carbocyclic or heterocyclic group containing up to three 3- to 8-membered carbocyclic or heterocyclic rings, wherein each carbocyclic or heterocyclic ring may be fused to one or more other carbocyclic or heterocyclic rings; X is a neutral or negatively charged N- or S-donor ligand; Y is a counterion; in is 0 or 1; q is 1, 2 or 3; C″ is C 1-12 alkylene bound to two A groups; p is 0 or 1 and r is 1 when p is 0 and r is 2 when p is 1; and A and B are each independently O-donor, N-donor or S-donor ligands, and may be connected to one another. The compounds are used in cancer therapy.
• Highly stereoselective bimetallic complexes for lactide and ε-caprolactone polymerization
  作者：Xuan Pang、Ranlong Duan、Xiang Li、Zhiqiang Sun、Han Zhang、Xianhong Wang、Xuesi Chen

  DOI：10.1039/c4ra11126e

  日期：——

  A series of Schiff-base compounds containing bimetallic ligands and two aluminum centers have been synthesized and characterized by 1H, 13C NMR and elemental analysis. These compounds could be successfully used as catalysts for the polymerization of rac-lactide and ε-caprolactone. The polylactides (PLAs) prepared with these compounds were highly isotactic enriched (Pm = 0.97). The nature and steric hindrance of the ligands coordinated to the central metal ions remarkably influenced the polymer properties. Kinetic studies revealed that the polymerization was first order with respect to each of these compounds and lactide/caprolactone monomers. All the polymerizations were living, with good molecular weight control and relatively narrow molar mass distributions.

  我们合成了一系列含有双金属配体和两个铝中心的希夫碱化合物，并通过 1H、13C NMR 和元素分析对其进行了表征。这些化合物可成功用作 rac-lactide 和 ε-caprolactone 聚合反应的催化剂。用这些化合物制备的聚乳酸（PLA）具有很高的同素异形富集度（Pm = 0.97）。与中心金属离子配位的配体的性质和立体阻碍显著影响了聚合物的特性。动力学研究表明，这些化合物和内酯/己内酯单体的聚合均为一阶聚合。所有聚合反应都是活的，分子量控制良好，摩尔质量分布相对较窄。