| 143668-69-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• CAS: 143668-69-3
• 化学式: C₁₈H₁₂N₂O₂
• 分子量: 288.305
• InChiKey: SPHABIHYWWAABH-FOIPXRHGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.69
• 重原子数：
  22.0
• 可旋转键数：
  2.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  58.86
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  在 吡啶 、 盐酸 作用下， 以 二氯甲烷 、 氯仿 为溶剂， 反应 25.0h， 生成 N-[(15S,16S)-16-(prop-2-enoylamino)-15-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl]prop-2-enamide
  参考文献：
  名称：

  Chiral selectors based on C2-symmetric dicarboxylic acids

  摘要：

  Bis-allylamides of rigid C-2-symmetric dicarboxylic acids, useful as precursors in the synthesis of liquid chromatographic chiral stationary phases via hydrosilylation reactions, have been prepared by two different approaches. One involved resolution of the dicarboxylic acid followed by reaction with allylamine via the acid chloride or by a carbodiimide-assisted condensation. The other route involved acetalization of N,N'-diallyl-L-tartardiamide (DATD) with aromatic aldehydes. Moreover, transformation of the enantiopure dicarboxylic acid used in the first route into the corresponding diamine permitted the synthesis of selectors possessing a reversed amide functionality. The enantiomer-discriminating properties of some of these selectors were studied by NMR. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(00)00331-1
• 作为产物：
  描述：

  9,10-ethenoanthracene-trans-11,12-dicarboxylic acid dichloride 在 sodium azide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 生成
  参考文献：
  名称：

  Chiral selectors based on C2-symmetric dicarboxylic acids

  摘要：

  Bis-allylamides of rigid C-2-symmetric dicarboxylic acids, useful as precursors in the synthesis of liquid chromatographic chiral stationary phases via hydrosilylation reactions, have been prepared by two different approaches. One involved resolution of the dicarboxylic acid followed by reaction with allylamine via the acid chloride or by a carbodiimide-assisted condensation. The other route involved acetalization of N,N'-diallyl-L-tartardiamide (DATD) with aromatic aldehydes. Moreover, transformation of the enantiopure dicarboxylic acid used in the first route into the corresponding diamine permitted the synthesis of selectors possessing a reversed amide functionality. The enantiomer-discriminating properties of some of these selectors were studied by NMR. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(00)00331-1