3-heptylfuran | 65434-77-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: 3-heptylfuran
• 英文别名: 3-n-heptylfuran
• CAS: 65434-77-7
• 化学式: C₁₁H₁₈O
• 分子量: 166.263
• InChiKey: IFLWCGXTQVNYFL-UHFFFAOYSA-N

物化性质

• 沸点：
  125-128 °C(Press: 25 Torr)
• 密度：
  0.886±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.64
• 拓扑面积：
  13.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (E/Z)-1-benzyloxy-3-(4-tolylsulfonyl)decene 在 正丁基锂 、 silica gel 作用下， 以 二氯甲烷 为溶剂， 反应 18.67h， 生成 3-heptylfuran
  参考文献：
  名称：

  (Alkoxyallyl)sulfones as enal and enone β-anion equivalents. Synthesis of mono-, di- and trisubtituted furans

  摘要：

  Treatment of variously-substituted (alkoxyallyl)sulfones 1, 7-9 with strong base followed by aldehydes gives alcohol adducts 5. These may be converted into a wide range of substituted furans 6 by exposure to acid, or to silica gel in dichloromethane containing sulfuric acid in some cases. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0040-4020(96)00932-5

文献信息

• PROCESS OF FORMING A PYRROLE COMPOUND
  申请人：Zhong Guofu

  公开号：US20110124881A1

  公开（公告）日：2011-05-26

  Disclosed is a process of forming a pyrrole compound. The process comprises contacting an α-carbonyl oxime compound 1 and an α,β-unsaturated aldehyde 2 R 1 and R 2 in compound 1 are independently selected from the group consisting of H, a silyl-group, an aliphatic group, an alicyclic group, an aromatic group, an arylaliphatic group, and an arylalicyclic group. The aliphatic, alicyclic, aromatic, arylaliphatic, and arylalicyclic groups comprise 0 to about 3 heteroatoms selected from the group N, O, S, Se and Si. R 3 in aldehyde 2 is selected from the group consisting of H, a silyl-group, an aliphatic group, an alicyclic group, an aromatic group, an arylaliphatic group, and an arylalicyclic group. The aliphatic, alicyclic, aromatic, arylaliphatic, and arylalicyclic groups comprise 0 to about 3 heteroatoms selected from the group N, O, S, Se and Si. The α-carbonyl oxime compound 1 an the α,β-unsaturated aldehyde 2 are contacted in a suitable solvent in the presence of a secondary amine. The compounds are contacted for a sufficient period of time to allow the formation of an N-hydroxypyrrole compound 3

  揭示了一种形成吡咯化合物的过程。该过程包括将α-羰基肟化合物1与α，β-不饱和醛2接触。化合物1中的R1和R2分别独立地选自H、硅基团、脂肪基、脂环基、芳香基、芳基脂肪基和芳基脂环基组成的群。脂肪、脂环、芳香、芳基脂肪基和芳基脂环基包括0到约3个来自N、O、S、Se和Si组成的杂原子。醛2中的R3选自H、硅基团、脂肪基、脂环基、芳香基、芳基脂肪基和芳基脂环基组成的群。脂肪、脂环、芳香、芳基脂肪基和芳基脂环基包括0到约3个来自N、O、S、Se和Si组成的杂原子。在适当的溶剂中，在次胺的存在下，将α-羰基肟化合物1和α，β-不饱和醛2接触。这些化合物接触一段足够的时间以允许形成N-羟基吡咯化合物3。
• NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS
  申请人：Loh Teck Peng

  公开号：US20110269972A1

  公开（公告）日：2011-11-03

  The present invention relates to a compound of general Formula (XX), its formation and its use in asymmetric catalysis. In Formula (XX) R and R 31 are independently —COOR 3 , —R 4 COOR 3 , —R 4 CHO, —R 4 COR 3 , —R 4 CONR 5 R 6 , —R 4 COX, —R 4 OP(═O)(OH) 2 , —R 4 P(═O)(OH) 2 ), —R 4 C(O)C(R 3 )CR 5 R 6 and —R 4 CO 2 COR 3 . In addition, R 31 may also be hydrogen. R 3 , R 5 and R 6 are independently hydrogen, an aliphatic group with a main chain having 1 to about 20 carbon atoms, an alicyclic group, an aromatic group, an arylaliphatic group or an arylalicyclic group, comprising 0 to about 3 heteroatoms independently selected from the group consisting of N, O, S, Se and Si. R 4 an aliphatic bridge with a main chain having 1 to about 20 carbon atoms, an alicyclic bridge, an aromatic bridge, an arylaliphatic bridge or an arylalicyclic bridge, comprising 0 to about 3 heteroatoms independently selected from the group consisting of N, O, S, Se and Si, and X is halogen. In Formula (XX) R 30 is —C(OH)R 1 R 2 or —COOR 14 , wherein R 1 , R 2 and R 14 are independently hydrogen, an aliphatic group with a main chain having 1 to about 20 carbon atoms, an alicyclic group, an aromatic group, an arylaliphatic group or an arylalicyclic group, comprising 0 to about 3 heteroatoms independently selected from the group consisting of N, O, S, Se and Si.

  本发明涉及一种一般式（XX）的化合物，其形成以及在不对称催化中的应用。在式（XX）中，R和R31独立地为—COOR3，—R4COOR3，—R4CHO，—R4COR3，—R4CONR5R6，—R4COX，—R4OP(═O)(OH)2，—R4P(═O)(OH)2，—R4C(O)C(R3)CR5R6和—R4CO2COR3。此外，R31也可以是氢。R3、R5和R6独立地为氢，具有主链含有1至约20个碳原子的脂肪基团，脂环基团，芳香基团，芳基脂基团或芳基脂环基团，包括0至约3个从N、O、S、Se和Si组成的杂原子。R4为具有主链含有1至约20个碳原子的脂肪桥，脂环桥，芳香桥，芳基脂桥或芳基脂环桥，包括0至约3个从N、O、S、Se和Si组成的杂原子，X为卤素。在式（XX）中，R30为—C(OH)R1R2或—COOR14，其中R1、R2和R14独立地为氢，具有主链含有1至约20个碳原子的脂肪基团，脂环基团，芳香基团，芳基脂基团或芳基脂环基团，包括0至约3个从N、O、S、Se和Si组成的杂原子。
• [EN] PROCESS OF FORMING A CYCLIC IMIDE<br/>[FR] PROCÉDÉ DE FORMATION D'UN IMIDE CYCLIQUE
  申请人：UNIV NANYANG TECH

  公开号：WO2012002913A1

  公开（公告）日：2012-01-05

  A process is provided for the synthesis of a cyclic imide. A primary amine and a diol compound are contacted in the presence of a Ruthenium (II) complex. The Ruthenium (II) catalyst includes at least one of an alicyclic ligand, an aromatic ligand, an arylalicyclic ligand, an arylaliphatic ligand and a phosphine ligand.

  提供一种合成环戊二酰亚胺的过程。在钌（II）配合物存在的情况下，将一种初级胺和一种二醇化合物接触。钌（II）催化剂包括至少一种脂环配体、芳香配体、芳基脂环配体、芳基脂肪配体和膦配体。
• MICHAEL REACTION WITH RECOVERY OF THE CATALYST
  申请人：ZHONG GUOFU

  公开号：US20120004424A1

  公开（公告）日：2012-01-05

  Disclosed is a process of carrying out a Michael reaction with recovery of the catalyst, where a compound of formula (1): is reacted with a compound of formula (2): in the presence of a catalyst of formula (4): where the compounds of formulae (1) and (2) undergo a Michael reaction.

  揭示了一种进行Michael加成反应并回收催化剂的过程，其中式（1）的化合物与式（2）的化合物在式（4）的催化剂存在下发生Michael反应。
• [EN] PROCESS OF FORMING AN AMIDE<br/>[FR] PROCÉDÉ DE FORMATION D'UN AMIDE
  申请人：UNIV NANYANG TECH

  公开号：WO2011034506A1

  公开（公告）日：2011-03-24

  A process is provided for the synthesis of an amide. A primary or secondary amine and a primary alcohol, with the amine and the alcohol being either moieties of different reactants or moieties of the same molecule, are contacted in the presence of a Ruthenium (II) catalyst. The Ruthenium (II) catalyst is free of a phosphine ligand. The process is also carried out in the absence of a phosphine. Providing the Ruthenium (II) catalyst includes providing an N-heterocyclic carbene.

  提供了一种合成酰胺的过程。在铑(II)催化剂的存在下，将一种初级或次级胺和一种初级醇接触，其中胺和醇可以是不同反应物的基团，也可以是同一分子的基团。铑(II)催化剂不含膦配体。该过程还在缺乏膦的情况下进行。提供铑(II)催化剂包括提供N-杂环卡宾。