6-diethylaminomethyl-2-allylphenol | 52741-92-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-diethylaminomethyl-2-allylphenol
• 英文别名: 2-(diethylaminomethyl)-6-allylphenol；2-Diethylaminomethyl-6-(2-propenyl)-phenol；2-N,N-diethylaminomethyl-6-allylphenol；2-allyl-6-(diethylamino-methyl)-phenol；2-Allyl-6-(diethylamino)methylphenol；2-(diethylaminomethyl)-6-prop-2-enylphenol
• CAS: 52741-92-1
• 化学式: C₁₄H₂₁NO
• 分子量: 219.327
• InChiKey: RRMUHLQDPIMXJL-UHFFFAOYSA-N

物化性质

• 沸点：
  300.4±32.0 °C(Predicted)
• 密度：
  0.988±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  6-diethylaminomethyl-2-allylphenol 、 亚磷酸二乙酯 在 亚磷酸三乙酯 作用下， 以 xylene 为溶剂， 反应 8.0h， 生成 2-ethoxy-7-prop-2-enyl-3H-1,2λ5-benzoxaphosphole 2-oxide
  参考文献：
  名称：

  Hydrolysis of substituted 2-ethoxy-2-oxo-1-oxa-2-phosphoindans

  摘要：

  DOI：

  10.1007/bf00953174
• 作为产物：
  描述：

  烯丙基苯基醚 生成 6-diethylaminomethyl-2-allylphenol
  参考文献：
  名称：

  Synthesis of aminomethylated derivatives of allylphenols and study of their antimicrobial characteristics in motor oil

  摘要：

  A series of nitrogen-containing compounds was synthesized by Mannich condensation of allylsubstituted derivatives of phenol and o- and p-cresols with formaldehyde and secondary amines. These compounds were studied as antimicrobial additives to motor oil (at a content of 1-2 wt %).

  DOI：

  10.1134/s1070427207040295

文献信息

• Dibromomethane as One‐Carbon Source in Organic Synthesis: The Mannich Base Formation from the Reaction of Phenolic Compounds with a Preheated Mixture of Dibromomethane and Diethylamine
  作者：Yung‐Son Hon、Yu‐Yu Chou、I‐Che Wu

  DOI：10.1081/scc-120038509

  日期：2004.12.31

  salt formed from the reaction of dihalomomethane and diethylamine reacted with phenolic compounds to give the corresponding Mannich bases in modest to good yields. As for the relative rates and yields are in the following order: CH2Br2 > CH2Cl2. The CD2Cl2 is also applicable to prepare the deuterated analogues. At higher temperature, the elimination of diethylamine from Mannich base occurred to give the

  摘要 二卤甲烷和二乙胺反应形成的盐与酚类化合物反应生成相应的曼尼希碱，收率适中。至于相对率和收率的顺序如下：CH2Br2>CH2Cl2。CD2Cl2 也适用于制备氘代类似物。在较高温度下，二乙胺从曼尼希碱中消除，得到相应的邻醌甲基化物中间体，然后被另一种酚类化合物捕获，得到双（2-羟基-1-芳基）甲烷。
• 10.1007/s11494-008-1012-x
  作者：Magerramov、Bairamov、Mekhtieva、Agaeva、Mamedova、Kulieva、Mamedov

  DOI：10.1007/s11494-008-1012-x

  日期：——
• Formation of alkoxyphosphoranes in reaction of substituted o-aminomethylphenols with trialkyl phosphites
  作者：B. E. Ivanov、L. A. Valitova、L. A. Kudryavtseva、T. G. Bykova、K. A. Derstuganova、E. I. Gol'dfarb

  DOI：10.1007/bf00921161

  日期：1974.3
• BELSKIJ, V. E.;KUDRYAVTSEVA, L. A.;DERSTUGANOVA, K. A.;VALITOVA, L. A.;BY+, IZV. AN CCCP. CEP. XIM., 1983, N 6, 1410-1412
  作者：BELSKIJ, V. E.、KUDRYAVTSEVA, L. A.、DERSTUGANOVA, K. A.、VALITOVA, L. A.、BY+

  DOI：——

  日期：——
• Synthesis and Study of 1-Alkenyl-2-propargyloxy-3-aminomethylbenzenes as Acid Corrosion Inhibitors and Antimicrobial Additives to Cutting Fluids
  作者：M. R. Bayramov、G. M. Askarova、G. M. Mehdiyeva、M. A. Agayeva、I. G. Mammadov、P. Sh. Mammadova、S. H. Jafarzadeh

  DOI：10.1134/s1070427220110026

  日期：2020.11