4-(1-methyl-1-phenyl-ethyl)-2-nitro-phenol | 24133-64-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(1-methyl-1-phenyl-ethyl)-2-nitro-phenol
• 英文别名: 4-(1-Methyl-1-phenyl-aethyl)-2-nitro-phenol；3-Nitro-4-hydroxy-1-(1-methyl-1-phenyl-aethyl)-benzol；2-<4-Hydroxy-3-nitro-phenyl>-2-phenyl-propan；4-<α-Phenyl-isopropyl>-2-nitro-phenol；2-Nitro-4-(α.α-dimethyl-benzyl)-phenol；2-Nitro-4-cumylphenol；Phenol, 4-(1-methyl-1-phenylethyl)-2-nitro-；2-nitro-4-(2-phenylpropan-2-yl)phenol
• CAS: 24133-64-0
• 化学式: C₁₅H₁₅NO₃
• 分子量: 257.289
• InChiKey: VOQITOVLCZFMRO-UHFFFAOYSA-N

物化性质

• 沸点：
  145 °C(Press: 15 Torr)
• 密度：
  1.208±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  66
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(1-methyl-1-phenyl-ethyl)-2-nitro-phenol 在 platinum on activated charcoal 作用下， 生成 2-amino-4-(1-methyl-1-phenyl-ethyl)-phenol
  参考文献：
  名称：

  Masitowa; Pauschkin, Doklady Akademii Nauk SSSR, 1959, vol. 125, p. 1033,1034

  摘要：

  DOI：
• 作为产物：
  描述：

  4-肉桂苯酚 在 硝酸 作用下， 生成 4-(1-methyl-1-phenyl-ethyl)-2-nitro-phenol
  参考文献：
  名称：

  Benzoxazoles and method of preparation

  摘要：

  公开号：

  US02429178A1

文献信息

• Nitration of Phenol and Substituted Phenols with Dilute Nitric Acid Using Phase-Transfer Catalysts
  作者：Ashutosh V. Joshi、Mubeen Baidoosi、Sudip Mukhopadhyay、Yoel Sasson

  DOI：10.1021/op0200120

  日期：2003.1.1

  Highly selective nitration of phenol and substituted phenols to the corresponding nitro compounds is accomplished under mild conditions in a liquid-liquid two-phase system with dilute nitric acid (6 wt %) and in the presence of a phase-transfer catalyst. The consequence of various phase-transfer catalysts on the reaction rate is contemplated. Tetrabutylammonium bromide (TBAB) was found to be the most effective phase-transfer catalyst in terms of conversion and selectivity. The experimental results are accounted for by a binary role of the phase-transfer catalyst in this system. It is anticipated to extract nitric acid into the organic phase via the hydrogen-bonded complex and to supply HBr, formed in situ in the reaction scheme by anion exchange, which is believed to be the key for generation of the active nitration species, nitronium ion in the organic phase.
• Sridharan; Karpagavalli; Muthusubramanian, Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004, vol. 43, # 10, p. 2243 - 2244
  作者：Sridharan、Karpagavalli、Muthusubramanian、Sivasubramanian

  DOI：——

  日期：——
• Benzoxocarbocyanines and method of preparation
  申请人：GEN ANILINE & FILM CORP

  公开号：US02441342A1

  公开（公告）日：1948-05-11
• CKYMOB M.; KYPTOB K., 2-A NATS. KONF. HA MLAD. NAUCHN. RABOTN. I SPETS.: NEFT I XIMIYA, BURGAS,+
  作者：CKYMOB M.、 KYPTOB K.

  DOI：——

  日期：——
• MLADENOV I.; KURTEV K.; BALBOLOV E.; KOSTOVA S., ZH. ORGAN. XIMII <ZORK-AE>, 1976, 12, HO 2, 323-325
  作者：MLADENOV I.、 KURTEV K.、 BALBOLOV E.、 KOSTOVA S.

  DOI：——

  日期：——