6-bromo-4-methyl-1,3-phenylene diisocyanate | 55206-98-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-bromo-4-methyl-1,3-phenylene diisocyanate
• 英文别名: 2,4-Diisocyanato-5-methyl-bromobenzene；1-bromo-2,4-diisocyanato-5-methylbenzene
• CAS: 55206-98-9
• 化学式: C₉H₅BrN₂O₂
• 分子量: 253.055
• InChiKey: XJVHGKZBKJPGIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  58.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  6-bromo-4-methyl-1,3-phenylene diisocyanate 、 异丙醇 以 四氯化碳 为溶剂， 反应 12.0h， 以86%的产率得到4-bromo-6-methyl-1,3-phenylenebisisopropylurethane
  参考文献：
  名称：

  Fetyukhin, V. N.; Kobrzhitskii, V. V.; Samarai, L. I., Journal of Organic Chemistry USSR (English Translation), 1987, vol. 23, p. 1909 - 1917

  摘要：

  DOI：
• 作为产物：
  描述：

  甲苯-2,4-二异氰酸酯 在 溴 作用下， 以 四氯化碳 为溶剂， 反应 2.0h， 以81%的产率得到6-bromo-4-methyl-1,3-phenylene diisocyanate
  参考文献：
  名称：

  Fetyukhin, V. N.; Kobrzhitskii, V. V.; Samarai, L. I., Journal of Organic Chemistry USSR (English Translation), 1987, vol. 23, p. 1909 - 1917

  摘要：

  DOI：

文献信息

• [EN] BISUREA GELLING AGENTS AND COMPOSITIONS<br/>[FR] AGENTS GÉLIFIANTS DE TYPE BIURÉE ET COMPOSITIONS ASSOCIÉES
  申请人：MILLIKEN & CO

  公开号：WO2013033300A1

  公开（公告）日：2013-03-07

  Bisurea gelling agents that impart a number of unexpected benefits within various gelled formulations and exhibit great versatility in terms of gelling capabilities for many types of solvents are provided. Such gelling agents should include pendant groups, such as sterically hindering alkyl groups attached to polyoxyalkylenated moieties that allow the gelling agent to be compatible with the target liquid system at elevated temperatures, while controlling and/or limiting the network formation and strength during the cooling cycle. The result is that a reliable, hard gel is formed that does not crash out of solution easily and that does not exhibit unwanted cracking or precipitating out within the final formulation. Alternatively, novel gelling agents having two urea groups but that are asymmetrical in configuration have been produced in order to provide the same control in temperature, compatibility, and efficiency. Final gelled formulations, such as antiperspirant sticks and other like consumer items, are provided as well within this invention.

  本文提供了一种Bisurea凝胶剂，它在各种凝胶配方中带来了许多意想不到的好处，并且在凝胶能力方面表现出极大的多样性，适用于许多类型的溶剂。这种凝胶剂应包括挂链基团，例如附加到聚氧烷基化物上的空间阻碍烷基基团，使凝胶剂在升高的温度下与目标液体系统兼容，同时在冷却周期中控制和/或限制网络形成和强度。结果是形成了可靠的坚硬凝胶，不易从溶液中崩解，不会在最终配方中出现不必要的开裂或沉淀。另外，为了提供相同的温度、兼容性和效率控制，还制备了具有两个脲基但配置不对称的新型凝胶剂。本发明还提供了最终的凝胶配方，例如止汗膏和其他类似的消费品。
• Novel antibacterial agents
  申请人：Christensen Burton G.

  公开号：US20090111737A1

  公开（公告）日：2009-04-30

  This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands has a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

  本发明涉及一种新型多结合化合物（药剂），其为抗菌剂。本发明的多结合化合物包括2-10个配体，这些配体通过连接剂或连接剂共价连接，其中每个单价（即未连接）的配体具有结合细胞壁生物合成和代谢酶、合成细菌细胞壁和/或细菌细胞表面的前体的能力，从而干扰细胞壁的合成和/或代谢。特别是，本发明的多结合化合物包括2-10个配体，这些配体通过连接剂或连接剂共价连接，其中每个配体具有能够结合青霉素结合蛋白、横肽酶酶、横肽酶酶底物、β-内酰胺酶酶、青霉素酶酶、头孢菌素酶酶、横链酶酶或横链酶酶底物的配体结构域；最好选择β-内酰胺类或糖肽类抗菌剂作为配体。
• Isocyanate- and isothiocyanate-modified polysilazane ceramic precursors
  申请人：LANXIDE TECHNOLOGY COMPANY, LP

  公开号：EP0442013A1

  公开（公告）日：1991-08-21

  Polysilazane addition polymers are prepared by (1) reacting ammonia with one or more halogenated organic silicon compounds to produce a cyclic silazane ammonolysis product and (2) reacting the ammonolysis product with from 0.1% to 30% by weight of an isocyanate, isothiocyanate, ketene, thioketene, carbodiimide, or carbon disulfide. Polysilazane addition polymers containing alkenyl or alkynyl groups can be cured by supplying energy to generate free radicals. The cured or uncured polymers can be pyrolyzed to produce silicon nitride-containing ceramic materials.

  聚硅氮烷加成聚合物的制备方法是：(1) 氨与一种或多种卤代有机硅化合物反应，生成环状硅氮烷氨解产物；(2) 氨解产物与 0.1% 至 30% （按重量计）的异氰酸酯、异硫氰酸盐、酮、硫酮、碳化二亚胺或二硫化碳反应。含有烯基或炔基的聚硅氧烷加成聚合物可以通过提供能量产生自由基来固化。固化或未固化的聚合物可热解生成含氮化硅的陶瓷材料。
• Thermosetting resin
  申请人：NITTO DENKO CORPORATION

  公开号：EP1512706A2

  公开（公告）日：2005-03-09

  The present invention provides a thermosetting resin which has a tensile modulus after cure of from 0.001 to 1 GPa at 35°C and which has a resin flow rate before cure under heat and pressure at 150°C and 2.94×10-1 MPa of from 5 to 50%.

  本发明提供了一种热固性树脂，其在 35°C 时固化后的拉伸模量为 0.001 至 1 GPa，在 150°C 和 2.94×10-1 MPa 的温度和压力下固化前的树脂流动率为 5 至 50%。
• Process for producing circuit board having built-in electronic part
  申请人：NITTO DENKO CORPORATION

  公开号：EP1555862A2

  公开（公告）日：2005-07-20

  The present invention provides a process for producing a circuit board (7) having built-in electronic parts (1), which comprises the steps of: disposing two wiring circuit boards (2) each having an electronic part (1) mounted thereon so that the electronic-part-mounting sides of the respective circuit boards (2) face each other; disposing a resin layer (3) between the circuit boards (2); and press-bonding the resin layer (3) to the circuit boards (2).

  本发明提供了一种用于生产内置电子零件（1）的电路板（7）的工艺，该工艺包括以下步骤：放置两块布线电路板（2），每块电路板（2）上都安装有一个电子零件（1），使各自电路板（2）的电子零件安装面相互面对；在电路板（2）之间放置一个树脂层（3）；以及将树脂层（3）压粘到电路板（2）上。