erythro-2-(1',1',4'-trimethyl-2'-methoxypenten-4'-yl)-3-(p-tolylthio)oxane

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: erythro-2-(1',1',4'-trimethyl-2'-methoxypenten-4'-yl)-3-(p-tolylthio)oxane
• 英文别名: (2S,3R)-2-[(3S)-3-methoxy-2,5-dimethylhex-5-en-2-yl]-3-(4-methylphenyl)sulfanyloxane
• 化学式: C₂₁H₃₂O₂S
• 分子量: 348.55
• InChiKey: ALTPILWPCPJOTH-HSALFYBXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  43.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-甲基苯硫氯 在 四氯化锡 作用下， 以 二氯甲烷 为溶剂， 反应 0.58h， 生成 erythro-2-(1',1',4'-trimethyl-2'-methoxypenten-4'-yl)-3-(p-tolylthio)oxane
  参考文献：
  名称：

  Reaction sequence arylsulfenyl chloride + alkoxyalkene-I + alkoxyalkene-II + allylmagnesium or boron derivatives as a new method for the controlled synthesis of polyfunctional derivatives

  摘要：

  A new method is proposed for the controlled synthesis of polyfunctional compounds with formation of two new carbon-carbon bonds; the method is based on the following reaction sequence, which can be carried out in a single flask: addition of ArSCl to vinyl ether I, reaction of the resultant adduct with vinyl ether II in the presence of Lewis acid to form a cationic complex, and treatment of the latter with allyl derivatives of boron or magnesium.

  DOI：

  10.1007/bf00961360

文献信息

• Reaction sequence arylsulfenyl chloride + alkoxyalkene-I + alkoxyalkene-II + allylmagnesium or boron derivatives as a new method for the controlled synthesis of polyfunctional derivatives
  作者：I. P. Smolyakova、V. A. Smit、Yu. N. Bubnov、A. S. Shashkov

  DOI：10.1007/bf00961360

  日期：1991.5

  A new method is proposed for the controlled synthesis of polyfunctional compounds with formation of two new carbon-carbon bonds; the method is based on the following reaction sequence, which can be carried out in a single flask: addition of ArSCl to vinyl ether I, reaction of the resultant adduct with vinyl ether II in the presence of Lewis acid to form a cationic complex, and treatment of the latter with allyl derivatives of boron or magnesium.