N-tosyl-bis(3-bromopropyl)amine | 1326626-47-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-tosyl-bis(3-bromopropyl)amine
• CAS: 1326626-47-4
• 化学式: C₁₃H₁₉Br₂NO₂S
• 分子量: 413.173
• InChiKey: WYNUQVHIIZRZNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.56
• 重原子数：
  19.0
• 可旋转键数：
  8.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  37.38
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  N-tosyl-bis(3-bromopropyl)amine 在 盐酸 、 水 作用下， 以 乙醇 、 二氯甲烷 、 乙腈 为溶剂， 反应 96.0h， 生成 N-tosyl-bis(3-mercaptopropyl)amine
  参考文献：
  名称：

  Synthesis and characterisation of new porphyrazinato magnesium containing macrobicyclic moieties

  摘要：

  Novel porphyrazinato magnesium (MgPz) containing symmetrically four diaza-tetrathia-macrobicycles on peripheral positions was synthesized by the cyclotetramerisation reaction of 5,8,16,23-tetrathia-1,12-diazabicyclo[9.7.7]pentacosane-6-en-6,7-dicarbodinitril (9), which was prepared by sequence reaction of N-tosyl-bis[3-bis(tosyloxypropyl)] amine (1) and disodium cis-1,2-dicyano-1,2-ethylenedithiolate (8). Elemental analysis, IR, NMR, MS and UV-vis data confirmed the ability of bulky cryptand moieties to induce steric isolation of Pz core in the solid state.

  DOI：

  10.1080/10610278.2011.575468
• 作为产物：
  描述：

  bis(3-tosyloxypropyl)tosylamine 在 sodium bromide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 5.5h， 以77.2%的产率得到N-tosyl-bis(3-bromopropyl)amine
  参考文献：
  名称：

  Synthesis and characterisation of new porphyrazinato magnesium containing macrobicyclic moieties

  摘要：

  Novel porphyrazinato magnesium (MgPz) containing symmetrically four diaza-tetrathia-macrobicycles on peripheral positions was synthesized by the cyclotetramerisation reaction of 5,8,16,23-tetrathia-1,12-diazabicyclo[9.7.7]pentacosane-6-en-6,7-dicarbodinitril (9), which was prepared by sequence reaction of N-tosyl-bis[3-bis(tosyloxypropyl)] amine (1) and disodium cis-1,2-dicyano-1,2-ethylenedithiolate (8). Elemental analysis, IR, NMR, MS and UV-vis data confirmed the ability of bulky cryptand moieties to induce steric isolation of Pz core in the solid state.

  DOI：

  10.1080/10610278.2011.575468