(E)-o-(but-2-en-2-yl)phenol | 62191-66-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-o-(but-2-en-2-yl)phenol
• 英文别名: trans-(But-2-en-2-yl)phenol；2-[(E)-but-2-en-2-yl]phenol
• CAS: 62191-66-6
• 化学式: C₁₀H₁₂O
• 分子量: 148.205
• InChiKey: AQHANRVDTSURKY-FPYGCLRLSA-N

物化性质

• 沸点：
  99-104 °C(Press: 15 Torr)
• 密度：
  0.996±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-o-(but-2-en-2-yl)phenol 、 氧化银 生成 2,3-二甲基苯呋喃
  参考文献：
  名称：

  CORNIA M.; MERLINI L.; ZANAROTTI A., GAZZ. CHIM. ITAL. , 1977, 107, NO 5-6, 229-304

  摘要：

  DOI：
• 作为产物：
  描述：

  2-(1-hydroxy-1-methyl-propyl)-phenol 生成 (E)-o-(but-2-en-2-yl)phenol
  参考文献：
  名称：

  Yasuda, Masahide; Sone, Tatsuya; Tanabe, Kimiko, Journal of the Chemical Society. Perkin transactions I, 1995, # 4, p. 459 - 464

  摘要：

  DOI：

文献信息

• [EN] TGFBETAR2 INHIBITOR-LRRC15 ANTIBODY CONJUGATES AND USES THEREOF<br/>[FR] CONJUGUÉS INHIBITEUR DE TGFBETAR2-ANTICORPS ANTI-LRRC15 ET LEURS UTILISATIONS
  申请人：SILVERBACK THERAPEUTICS INC

  公开号：WO2021102332A1

  公开（公告）日：2021-05-27

  Conjugates comprising a TGFβR2 inhibitor and an anti-LRRC15 antibody, compositions comprising the conjugates, and use of the conjugates in the treatment of disease, such as fibrosis and cancer, are disclosed herein. Also disclosed herein are anti-LRRC15 antibodies, including humanized anti-LRRC15 antibodies.

  本文披露了包括TGFβR2抑制剂和抗LRRC15抗体在内的共轭物，包括这些共轭物的组合物，以及在治疗疾病（如纤维化和癌症）中使用这些共轭物的方法。本文还披露了抗LRRC15抗体，包括人源化的抗LRRC15抗体。
• Perfume composition and perfumed products which contain one or more o-alkoxyphenols as perfume component
  申请人：NAARDEN INTERNATIONAL N.V.

  公开号：EP0179532A1

  公开（公告）日：1986-04-30

  Parfume compositions and perfumed products characterized by a content of one or more fragrances which have the wherein R, or R, represents a hydrogen atom and the other symbol an ethyl or propyl group and R, represents a methyl or ethyl group. characteristic odour of vanilla and correspond to the formula

  香水组合物和香料产品，其特征在于含有一种或多种香料，这些香料具有 R 或 R 代表氢原子，另一个符号代表乙基或丙基，而 R 代表甲基或乙基。 具有香草的特征气味，并符合以下公式
• Poly(epoxide) coatings containing a mannich base of a hydroxystyrene containing polymer
  申请人：HOECHST CELANESE CORPORATION

  公开号：EP0355984A2

  公开（公告）日：1990-02-28

  A coating composition which is a uniformly dispersed admixture of A. a fluid carrier; and B. a homopolymer or copolymer containing monomer units of the formula wherein R₁ and R₂ are preferably hydroxyalkyl and the polymer has a preferred average molecular weight in the range of from about 5,000 to about 30,000; and C. a poly(epoxide).

  一种涂料组合物，它是以下物质均匀分散的混合物 A. 流体载体；和 B. 含式中单体单元的均聚物或共聚物 其中 R₁ 和 R₂ 优选为羟烷基，聚合物的优选平均分子量在约 5,000 至约 30,000 之间；以及 C. 聚环氧化物。
• Protective coatings of a cured hydroxystyrene mannich base and blocked polyisocyanates
  申请人：HOECHST CELANESE CORPORATION

  公开号：EP0352950A2

  公开（公告）日：1990-01-31

  A coating composition which is a uniformly dispersed admixture of A. a fluid carrier; and B. a homopolymer or copolymer containing monomer units of the formula wherein R₁ and R₂ are preferably hydroxyalkyl and the polymer has a preferred average molecular weight in the range of from about 5,000 to about 30,000; and C. a blocked polyisocyanate.

  一种涂料组合物，它是以下物质均匀分散的混合物 A. 流体载体；和 B. 含式中单体单元的均聚物或共聚物 其中 R₁ 和 R₂ 优选为羟烷基，聚合物的优选平均分子量在约 5,000 至约 30,000 之间；以及 C. 嵌段聚合异氰酸酯。
• Curable compositions
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0399350A2

  公开（公告）日：1990-11-28

  Adducts of an epoxy resin and a compound containing at least one aromatic hydroxyl group and at least one polymerizable ethylenically unsaturated group per molecule are prepared which are optionally reacted with water, a secondary amine or a phenol which product is copolymerized with a polymerizable monoethylenically unsaturated carboxylic acid and a polymerizable monoethylenically unsaturated compound free of carboxylic acid groups. This product is rendered water miscible by reaction with a primary, secondary or tertiary amine or an alkali metal hydroxide, carbonate or bicarbonate. This product can then be cured with any suitable curing agent such as phenol/aldehyde compounds, urea/aldehyde compounds and melamine/aldehyde compounds and blocked isocyanates.

  制备环氧树脂和一种每分子含有至少一个芳香羟基和至少一个可聚合乙烯不饱和基团的化合物的加合物，该加合物可选择与水、仲胺或苯酚反应，其产物与一种可聚合单乙烯不饱和羧酸和一种不含羧酸基团的可聚合单乙烯不饱和化合物共聚。通过与伯胺、仲胺或叔胺或碱金属氢氧化物、碳酸盐或碳酸氢盐反应，使该产品与水混溶。然后，可使用任何合适的固化剂（如苯酚/甲醛化合物、脲/甲醛化合物、三聚氰胺/甲醛化合物和封端异氰酸酯）对该产品进行固化。