1-烯丙基-4-苯氧基苯 | 2653-93-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 1-烯丙基-4-苯氧基苯
• 英文名称: 4-allyl-1-phenoxybenzene
• 英文别名: 1-phenoxy-4-(prop-2-en-1-yl)benzene；1-allyl-4-(phenoxy)benzene；p-Phenoxyallylbenzol；4-Allyl-diphenylether；3-(4-Phenoxyphenyl)-1-propene；1-phenoxy-4-prop-2-enylbenzene
• CAS: 2653-93-2
• 化学式: C₁₅H₁₄O
• 分子量: 210.276
• InChiKey: WJFCDMWSDIGUPN-UHFFFAOYSA-N

物化性质

• 沸点：
  127-130 °C(Press: 2 Torr)
• 密度：
  1.0423 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2909309090

反应信息

• 作为反应物：
  描述：

  1-烯丙基-4-苯氧基苯 在 咪唑 、 甲醇 、 9-borabicyclo[3.3.1]nonane dimer 、 正丁基锂 、 碘 、 potassium carbonate 、 三苯基膦 作用下， 以 甲苯 为溶剂， 生成
  参考文献：
  名称：

  Design, synthesis and cytotoxicity of 7-deoxy aryl discodermolide analogues

  摘要：

  A series of 7-deoxy discodermolide analogues in which the lactone fragment 'C' was replaced by aryl substituents were designed, synthesized, and evaluated for cytotoxicity. (C) 2004 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2004.01.102
• 作为产物：
  描述：

  二苯醚 生成 1-烯丙基-4-苯氧基苯
  参考文献：
  名称：

  Thermal polymerization of p-allylphenyl phenyl ether

  摘要：

  DOI：

  10.1007/bf01176041

文献信息

• Zinc-Mediated Intermolecular Reductive Radical Fluoroalkylsulfination of Unsaturated Carbon-Carbon Bonds with Fluoroalkyl Bromides and Sulfur Dioxide
  作者：Yongan Liu、Qiongzhen Lin、Zhiwei Xiao、Changge Zheng、Yong Guo、Qing-Yun Chen、Chao Liu

  DOI：10.1002/chem.201805526

  日期：2019.2.1

  general zinc‐mediated intermolecular reductive radical fluoroalkylsulfination of unsaturated C−C bonds has been developed using readily available fluoroalkyl bromides and 1,4‐diazabicyclo[2.2.2]octane‐bis(sulfur dioxide) adduct (DABSO) with wide substrate scope and excellent functional group tolerance. Sulfur dioxide anion radical generated in situ from the reduction of sulfur dioxide with zinc may be

  使用易于获得的氟代烷基溴和具有宽底物的1,4-二氮杂双环[2.2.2]辛烷-双（二氧化硫）加合物，开发了一种通用且通用的锌介导的不饱和C-C间分子间还原性自由基氟代烷基硫化物。范围和出色的功能组耐受性。由锌还原二氧化硫而原位产生的二氧化硫阴离子自由基可能参与了反应机理。
• Oxidative radical phosphonotrifluoromethylthiolation of unactivated alkenes with alkyl phosphonate, silver(I) trifluoromethanethiolate and potassium persulfate
  作者：Zhiwei Xiao、Yongan Liu、Liping Zheng、Xiumiao Zhou、Youzhuan Xie、Chao Liu、Yong Guo、Qing-Yun Chen

  DOI：10.1016/j.tet.2018.09.019

  日期：2018.10

  We report herein a mild and efficient oxidative radical intermolecular phosphonotrifluoromethylthiolation of unactivated alkenes with good functional group tolerance. The reaction operates via a radical pathway involving oxidative generation of phosphonyl radicals and umpolung radical coupling of silver trifluoromethanethiolate.

  我们在本文中报道了具有良好官能团耐受性的未活化烯烃的温和且有效的氧化自由基分子间膦酰三氟甲基硫醇化。该反应通过自由基途径进行，该自由基途径涉及氧化生成膦酰基自由基和三氟甲硫醇银的酚基自由基偶联。
• Polar influences in radical reactions. Part VII. Hydrogen abstraction from nuclear-substituted diphenylmethanes, deoxybenzoins, and allylbenzenes by atomic bromine
  作者：T. P. Low、Kheng H. Lee

  DOI：10.1039/j29700000535

  日期：——

  The relative reactivities of nuclear-substituted diphenylmethanes, deoxybenzoins (X·C6H4·CH2Bz), and allylbenzenes towards atomic bromine at 80° have been determined by means of competitive reactions by use of allylbenzene, diphenylmethyl methyl ether, and p-bromoethylbenzene, respectively, as reference standard. The results show ρ-values of –0·93, –0·92, and –0·68 by the Hammett equation for the three

  核取代的二苯基甲烷的相对反应性，deoxybenzoins（X·C 6 H ^ 4 ·CH 2 BZ）°已经通过竞争反应的手段通过使用烯丙基苯的确定，并在80朝原子溴allylbenzenes，二苯基甲基醚，和p -溴乙基苯分别作为参考标准。结果表明，通过哈米特方程，三个系统的ρ值分别为–0·93，–0·92和–0·68，前两个系统的σ-常数相关性更好，而在第三个系统中σ + -常数与先前的报告具有更好的相关性。与σ相关的可能原因-常量将被讨论。这些系统的ρ值与先前观察到的反应性值具有一致的反比关系。
• Palladium-catalyzed prenylation of (hetero)aryl boronic acids
  作者：Jeffrey Leister、Darrian Chao、Kelvin L. Billingsley

  DOI：10.1016/j.tetlet.2020.152800

  日期：2021.3

  cross-coupling of aryl and heteroaryl boronic acids with prenyl alcohol. Catalyst systems based on dialkylbiaryl phosphines were highly active for this transformation. These supporting ligands provided opportunities for tuning the efficiency and regioselectivity of carbon–carbon bond formation. In addition, this method was further extended to the cross-coupling of symmetrical allylic alcohols with aryl boronic

  异戊二烯基或二甲基烯丙基是天然产物和小分子治疗剂中常见的结构基序。在这份报告中，我们描述了钯催化的芳基和杂芳基硼酸与异戊二烯醇的交叉偶联方法。基于二烷基联芳基膦的催化剂体系对该转化具有很高的活性。这些辅助配体为调节碳-碳键形成的效率和区域选择性提供了机会。另外，该方法进一步扩展到对称的烯丙基醇与芳基硼酸的交叉偶联。
• Visible light promoted iodofluoroalkylation of alkenes with iodo-3-oxaperfluoroalkanesulphonates
  作者：Dongmei He、Yong Guo、Qing-Yun Chen、Hu Yang、Tao Lv

  DOI：10.1016/j.jfluchem.2019.03.008

  日期：2019.6

  fluorides (I(CF2CF2)n+1OCF2CF2SO2F, n = 0, 1, 2, 3) was functionalized by phenol to provide phenyl fluoroalkanesulfonate. The ATRA reaction of I(CF2CF2)n+1OCF2CF2SO3Ph with alkenes was realized by visible light phototcatalysis with Ru(ppy)3Cl2.

  通过苯酚使碘-3-氧杂-全氟链烷磺酸磺酰氟（I（CF 2 CF 2）n + 1 OCF 2 CF 2 SO 2 F，n = 0、1、2、3）官能化，得到氟代链烷磺酸苯基酯。I（CF 2 CF 2）n + 1 OCF 2 CF 2 SO 3 Ph与烯烃的ATRA反应是通过可见光催化Ru（ppy）3 Cl 2进行的。