(3,4-dimethyl-phenyl)-acetic acid ethyl ester | 105337-17-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3,4-dimethyl-phenyl)-acetic acid ethyl ester
• 英文别名: (3,4-Dimethyl-phenyl)-essigsaeure-aethylester；3,4-Dimethyl-phenyl-essigsaeure-ethylester；3,4-Dimethyl-phenylessigsaeure-ethylester；Ethyl 2-(3,4-dimethylphenyl)acetate
• CAS: 105337-17-5
• 化学式: C₁₂H₁₆O₂
• mdl: MFCD11555022
• 分子量: 192.258
• InChiKey: XAELHIMYKNBOSE-UHFFFAOYSA-N

物化性质

• 沸点：
  120-130 °C(Press: 7 Torr)
• 密度：
  1.004±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.416
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (3,4-dimethyl-phenyl)-acetic acid ethyl ester 、 C.I.酸性橙108 生成 (3,4-dimethyl-phenyl)-acetic acid-(2-hydroxy-ethylamide)
  参考文献：
  名称：

  青霉素的生物合成；取代的苯乙酸衍生物作为青霉素的前体。

  摘要：

  DOI：

  10.1021/ja01189a001
• 作为产物：
  描述：

  3,4-二甲基氯苄 在 硫酸 作用下， 以 乙醇 为溶剂， 生成 (3,4-dimethyl-phenyl)-acetic acid ethyl ester
  参考文献：
  名称：

  van Zanten,B.; Nauta,W., Recueil des Travaux Chimiques des Pays-Bas, 1960, vol. 79, p. 1211 - 1222

  摘要：

  DOI：

文献信息

• Non-nucleoside reverse transcriptase inhibitors
  申请人：Mirzadegan Taraneh

  公开号：US20070088053A1

  公开（公告）日：2007-04-19

  The present invention provides for compounds useful for treating an HIV-1 infection, or preventing an HIV-1 infection, or treating AIDS or ARC. The compounds of the invention are of formula I wherein R1-R4 and Ar are as herein defined. Also disclosed in the present invention are methods of treating an HIV-1 infection with compounds defined herein and pharmaceutical compositions containing said compounds.

  本发明提供了用于治疗HIV-1感染、预防HIV-1感染、治疗AIDS或ARC的化合物。本发明的化合物具有以下式I的结构，其中R1-R4和Ar如本文所定义。本发明还公开了使用本文所定义的化合物治疗HIV-1感染的方法以及含有这些化合物的药物组合物。
• Nonnucleoside reverse transcriptase inhibitors
  申请人：Dunn Patrick James

  公开号：US20070179157A1

  公开（公告）日：2007-08-02

  This invention relates to methods of treating an HIV infection with novel heterocyclic compounds of formula I wherein R 1 —R 4 , X 1 and X 2 are as defined in the summary and pharmaceutically acceptable salts, and methods to inhibit or modulate Human Immunodeficiency Virus (HIV) reverse transcriptase with compounds of formula I.

  本发明涉及使用公式I中的新异环化合物治疗HIV感染的方法，其中R1-R4，X1和X2如摘要中所定义，并且包括药学上可接受的盐，以及使用公式I中的化合物抑制或调节人类免疫缺陷病毒（HIV）反转录酶的方法。
• METHODS FOR TREATING RETROVIRAL INFECTIONS
  申请人：Dunn James Patrick

  公开号：US20100041648A1

  公开（公告）日：2010-02-18

  The present invention provides compositions for treating an HIV infection comprising administering a compound according to formula I where Ar, R 1 -R 5 , R 11c and X 1 are as defined herein with at least one carrier, excipient or diluent.

  本发明提供了用于治疗HIV感染的组合物，其包括按照式I给出的化合物与至少一种载体、赋形剂或稀释剂一起使用，其中Ar、R1-R5、R11c和X1的定义如本文所述。
• US2479295
  申请人：——

  公开号：——

  公开（公告）日：——
• MAGNETIC RECORDING MEDIUM AND MAGNETIC COATING COMPOSITION FOR MAGNETIC RECORDING MEDIUM
  申请人：FUJIFILM Corporation

  公开号：US20150279403A1

  公开（公告）日：2015-10-01

  An aspect of the present invention relates to a magnetic recording medium, which comprises a magnetic layer comprising ferromagnetic powder and binder on a nonmagnetic support, wherein the magnetic layer further comprises a compound which has a weight average molecular weight of equal to or more than 1,000 but less than 20,000 and is denoted by formula (1): wherein, in formula (1), A denotes a monovalent substituent, R 1 denotes a single bond or a divalent connecting group, and m denotes an integer ranging from 2 to 4, multiple instances of A and R 1 that are present can be identical or different, at least one of the multiple instances of A that are present denotes a monovalent polymer group and X denotes a heterocyclic group of valence m.