p-Toluolsulfonsaeure-divinylamid | 91133-25-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: p-Toluolsulfonsaeure-divinylamid
• 英文别名: N,N-divinyl-toluene-4-sulfonamide；N,N-Divinyl-toluol-4-sulfonamid；4-methyl-N,N-divinylbenzenesulfonamide；N,N-bis(ethenyl)-4-methylbenzenesulfonamide
• CAS: 91133-25-4
• 化学式: C₁₁H₁₃NO₂S
• 分子量: 223.296
• InChiKey: YOGRQXADHJUDHR-UHFFFAOYSA-N

物化性质

• 熔点：
  49-50 °C
• 沸点：
  324.3±35.0 °C(Predicted)
• 密度：
  1.148±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  p-Toluolsulfonsaeure-divinylamid 在 三(五氟苯基)硼烷 作用下， 以 二氯甲烷 为溶剂， 以55 %的产率得到7-methyl-2,6-ditosyl-2,6-diazabicyclo[3.3.1]non-3-ene
  参考文献：
  名称：

  三氢硅烷在合成具有多种甲硅烷基官能团的 1,4-氮杂硅烷过程中可控 Si-C 键的形成

  摘要：

  AB(C 6 F 5 ) 3催化的可控分子间/分子内/分子间Si-C键形成过程是由三氢硅烷和二烯酰胺与烯烃、苯胺或芳基碘化物开发而成。已经通过硅上的多种外环杂配取代生成了多种1,4-氮杂硅烷，从而扩大了可用于发现含硅药物的硅氮杂环的范围。

  DOI：

  10.1021/acs.orglett.3c03014
• 作为产物：
  描述：

  N,N-双-2-氯乙基对甲苯磺酸胺 在 potassium tert-butylate 、 叔丁醇 作用下， 以12.5 g的产率得到p-Toluolsulfonsaeure-divinylamid
  参考文献：
  名称：

  三氢硅烷在合成具有多种甲硅烷基官能团的 1,4-氮杂硅烷过程中可控 Si-C 键的形成

  摘要：

  AB(C 6 F 5 ) 3催化的可控分子间/分子内/分子间Si-C键形成过程是由三氢硅烷和二烯酰胺与烯烃、苯胺或芳基碘化物开发而成。已经通过硅上的多种外环杂配取代生成了多种1,4-氮杂硅烷，从而扩大了可用于发现含硅药物的硅氮杂环的范围。

  DOI：

  10.1021/acs.orglett.3c03014

文献信息

• Modular Synthesis of Alkylarylazo Compounds via Iron(III)-Catalyzed Olefin Hydroamination
  作者：Yan Zhang、Chenchao Huang、Xinru Lin、Qi Hu、Boyue Hu、Yulu Zhou、Gangguo Zhu

  DOI：10.1021/acs.orglett.9b00540

  日期：2019.4.5

  A novel Fe-catalyzed olefin hydroamination with aryldiazo sulfones for accessing alkylarylazo compounds has been successfully developed. Aryldiazo sulfones are used as radical acceptors, and N–N double bonds will be regenerated when an arene sulfonyl group leaves. The reaction features mild reaction conditions and a broad substrate scope, allowing access to many azo compounds that would be difficult

  已经成功开发了一种新的用芳基重氮砜进行铁催化的烯烃加氢胺化反应，以得到烷基芳基偶氮化合物。芳基重氮砜被用作自由基受体，当芳烃磺酰基离开时，N–N双键将被再生。该反应具有温和的反应条件和广泛的底物范围，从而允许获得许多使用其他方法难以或可能无法获得的偶氮化合物。
• MULTISENSOR ARRAY FOR DETECTION OF ANALYTES OR MIXTURES THEREOF IN GAS OR LIQUID PHASE
  申请人：Jeppesen Jan Oskar

  公开号：US20130096030A1

  公开（公告）日：2013-04-18

  The present invention relates to a multisensor array for detection of analytes in the gas phase or in the liquid phase, comprising at least two different chemo-selective compounds represented by the general formula (I) wherein the hetero atoms X 1 -X 4 and the substituents R 1 -R 4 are defined in the specification and the dashed bonds represent independently of each other either a single bond or a double bond. Said chemo-selective compounds are capable of individually changing physicochemical properties when exposed to analytes or analyte mixtures and these changes can be detected by a transducer or an array of transducers. The present invention does also relate to the use of at least two different chemo-selective compounds in a sensor array, a method for preparation of such sensor arrays and the use of said sensor arrays. Furthermore the present invention relates to methods for detecting and identifying analytes or mixtures thereof in the gas phase or in the liquid phase.

  本发明涉及一种多传感器阵列，用于检测气相或液相中的分析物，包括至少两种不同的化学选择性化合物，由一般式（I）表示，其中杂原子X1-X4和取代基R1-R4在说明书中定义，虚线键独立地表示单键或双键。所述化学选择性化合物在暴露于分析物或分析物混合物时能够单独改变物理化学性质，这些变化可以被传感器或传感器阵列检测到。本发明还涉及在传感器阵列中使用至少两种不同的化学选择性化合物，制备这种传感器阵列的方法以及使用该传感器阵列的方法。此外，本发明还涉及检测和鉴定气相或液相中的分析物或混合物的方法。
• Synthesis and complexation properties of suitcase-shaped macrotricyclic and butterfly-shaped macrobicyclic polyether ligands
  作者：Haoyun An、Jerald S. Bradshaw、Krzysztof E. Krakowiak、Chengyue Zhu、N. Kent Dalley、Reed M. Izatt

  DOI：10.1021/jo00044a040

  日期：1992.8

  Ten suitcase-shaped macrotricyclic polyethers (1-10) containing nitrogen and carbon bridgehead atoms have been synthesized. These new cage compounds were prepared by connecting together two hydroxymethyl-substituted or two secondary amine-containing butterfly-shaped macrobicyclic polyethers by means of linear bifunctional connecting groups. Intermediate bis(hydroxymethyl)-substituted butterfly-shaped macrobicyclic polyether 14 was prepared by treating N,N'-bis(2-hydroxyethyl)ethylenediamine with 5-methylene-3,7-dioxanonane-1,9-diyl ditosylate to give bislariat 1,4-diaza-13-crown-4 (11) which was cyclized with 3-chloro-2-(chloromethyl)-l-propene followed by hydroboration. Intermediate bissecondary amine-contaminating butterfly shaped macrobicyclic polyethers 18 and 19 were prepared by treating N,N'-bis(2-hydroxyethyl)ethylenediamine with 6-tosyl-3,9-dioxa-6-aza-1,11-undecanediyl ditosylate (33) to give N-tosyl-N,N"-bis(2-hydroxyethyl)triaza-15-crown-5 (12). Lariat crown ether 12 was cyclized with 33 followed by reduction with LiAlH4 to give 18, or with 4-tosyl-4-aza-1,7-heptanediyl ditosylate (36) to give 19. Some of the suitcase-shaped macrotricycles interacted with various cations. One was selective for Pb2+ ions and another interacted strongly with Hg2+. A crystal structure for the 13-NaClO4 complex also is reported.
• Buechi et al., Il Farmaco, scienza e tecnica, 1951, vol. 6, p. 429,433
  作者：Buechi et al.

  DOI：——

  日期：——
• US9671392B2
  申请人：——

  公开号：US9671392B2

  公开（公告）日：2017-06-06