[5-Methyl-2-methylene-cyclohex-(E)-ylidenemethyl]-benzene | 130954-53-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [5-Methyl-2-methylene-cyclohex-(E)-ylidenemethyl]-benzene
• 英文别名: [(E)-(5-methyl-2-methylidenecyclohexylidene)methyl]benzene
• CAS: 130954-53-9
• 化学式: C₁₅H₁₈
• 分子量: 198.308
• InChiKey: ZJULTANHUSRUPA-RVDMUPIBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  [5-Methyl-2-methylene-cyclohex-(E)-ylidenemethyl]-benzene 以 苯 为溶剂， 以45%的产率得到2-甲基-1,2,3,4-四氢蒽
  参考文献：
  名称：

  A photoannulation route to naphthalenes from cyclic ketones

  摘要：

  A three-step naphthalene annulation of cyclic ketones has been developed. Aldol condensation with an aromatic aldehyde followed by Wittig olefination produces a 1,3-diene, which undergoes oxidative photocyclization to produce a naphthalene derivative. Ketone ring sizes of C5 to C8 were annulated successfully. The sequence was also applied successfully to three methyl-substituted derivatives and one polycyclic case.

  DOI：

  10.1021/jo00003a018
• 作为产物：
  描述：

  2-Benzyliden-4-methylcyclohexanon 、 甲基三苯基碘化鏻 在 正丁基锂 作用下， 生成 [5-Methyl-2-methylene-cyclohex-(E)-ylidenemethyl]-benzene
  参考文献：
  名称：

  A photoannulation route to naphthalenes from cyclic ketones

  摘要：

  A three-step naphthalene annulation of cyclic ketones has been developed. Aldol condensation with an aromatic aldehyde followed by Wittig olefination produces a 1,3-diene, which undergoes oxidative photocyclization to produce a naphthalene derivative. Ketone ring sizes of C5 to C8 were annulated successfully. The sequence was also applied successfully to three methyl-substituted derivatives and one polycyclic case.

  DOI：

  10.1021/jo00003a018

文献信息

• OLSEN, ROBERT J.;MINNIEAR, JOHN C.;OVERTON, W. MACK;SHERRICK, JOHN M., J. ORG. CHEM., 56,(1991) N, C. 989-991
  作者：OLSEN, ROBERT J.、MINNIEAR, JOHN C.、OVERTON, W. MACK、SHERRICK, JOHN M.

  DOI：——

  日期：——