dichloro(o-diphenylphosphino-N,N-dimethylbenzylamine)palladium | 53897-10-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: dichloro(o-diphenylphosphino-N,N-dimethylbenzylamine)palladium
• 英文别名: palladium(II)(Ph2PC6H402-(CH2NMe2))Cl2
• CAS: 53897-10-2
• 化学式: C₂₁H₂₂Cl₂NPPd
• 分子量: 496.712
• InChiKey: XMNGWUHQGABDNG-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  dichloro(o-diphenylphosphino-N,N-dimethylbenzylamine)palladium 、 potassium iodide 以 二氯甲烷 、 丙酮 为溶剂， 以91 %的产率得到
  参考文献：
  名称：

  Problematic Ar^F–Alkynyl Coupling with Fluorinated Aryls. From Partial Success with Alkynyl Stannanes to Efficient Solutions via Mechanistic Understanding of the Hidden Complexity

  摘要：

  DOI：

  10.1021/jacs.2c10842
• 作为产物：
  描述：

  dichloro(cycloocta-1,5-diene)palladium (II) 、 [2-(N,N-dimethylaminomethyl)phenyl]diphenylphosphane 以 二氯甲烷 为溶剂， 以95%的产率得到dichloro(o-diphenylphosphino-N,N-dimethylbenzylamine)palladium
  参考文献：
  名称：

  Pd catalyzed Heck reaction with the catalytic system [Pd(Ph2PC6H4-2-(CH2NMe2))(SRF)2]

  摘要：

  A series of palladium thiolate complexes of the [Pd(Ph2PC6H4-2-(CH2NMe2))(SRF)(2)] type have been synthesized in good yields by metathetical reactions of [Pd(Ph2PC6H4-2-(CH2NMe2))Cl-2] (1) with [Pb(SRF)(2)], (SRF = -SC6F5, -SC6F4-H, -SC6H4-2-CF3, -SC6H4-4-F, -SC6H4-2-F) and their crystal structures determined. Heck coupling reactions were carried out using [Pd(PhPC6H4-2-(CH2NMe2))(SRF)2], SRF = -SC6F5(2), -SC6F4-4-H(3), -SC6H4-2-CF3 (4), -SC6H4-4-F (5), -SC6H4-2-F (6) complexes as catalysts in order to examine the effect of the thiolates in the reaction of bromobenzene and styrene. The results obtained indicate that the less electron-withdrawing substituents on the thiolate moiety may favor higher yields in the Pd catalyzed Heck reaction using [Pd(Ph2PC6H4-2-(CH2NMe2))(SRF)(2)] as catalysts. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2005.02.007

文献信息

• Organopalladium complexes with bidentate phosphorus and nitrogen containing ligands
  作者：Wim de Graaf、Sjoerd Harder、Jaap Boersma、Gerard van Koten、Jan A. Kanters

  DOI：10.1016/0022-328x(88)87102-x

  日期：1988.12

  Organopalladium complexes containing the potentially P,N-bidentate ligands o-diphenylphosphino-N,N-dimethylbenzylamine (PN) and o-diphenylphosphino-α-methyl-N,N-dimethylbenzylamine (PN*) have been studied. The palladium(0) complexes Pd(PN)3 (PN = PN or PN*) have been prepared: the ligands coordinate to the metal primarily through phosphorus, with the amine function coordinating not at all or only

  有机钯含有潜在P，N二齿配体的络合物ø -diphenylphosphino- Ñ，Ñ -dimethylbenzylamine（PN）和ö -diphenylphosphino-α甲基Ñ，Ñ -dimethylbenzylamine（PN *）进行了研究。钯（0）络合物Pd（PN）3（PN= PN或PN *制备）：配体主要通过磷与金属配位，而胺官能团完全不配位或仅非常弱地配位。将几种有机卤化物氧化添加到这些钯（0）络合物中，得到相应的单有机钯（II）络合物Pd（R）（X）（PN），其中供体配体是P，N-双配位的。溶液中的二价物种具有一个PdN键，并且即使在任一游离配位体，CO或X的存在-存在用于从金属中心的胺官能团的离解和置换没有证据。配合物PdMe 2（PN）由相应的二卤钯配合物通过MeLi处理制得。这些二甲基钯物种与亲电试剂MeI，MeBr和PhCH 2的反应Br导致一个甲