N,N'-Bis-(2-methoxy-benzyl)-ethylendiamin | 58015-12-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-Bis-(2-methoxy-benzyl)-ethylendiamin
• 英文别名: N,N'-bis[(2-methoxyphenyl)methyl]ethane-1,2-diamine
• CAS: 58015-12-6
• 化学式: C₁₈H₂₄N₂O₂
• 分子量: 300.401
• InChiKey: VIIDLDKEUMYZNZ-UHFFFAOYSA-N

物化性质

• 沸点：
  427.7±35.0 °C(Predicted)
• 密度：
  1.066±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  22
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  42.5
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N,N'-Bis-(2-methoxy-benzyl)-ethylendiamin 、 N,N-二乙基-4-氨基苯甲醛 以77%的产率得到4-[1,3-bis[(2-methoxyphenyl)methyl]imidazolidin-2-yl]-N,N-diethylaniline
  参考文献：
  名称：

  Synthesis of novel tetrahydroimidazole derivatives and studies for their biological properties

  摘要：

  Ethylenediamine was reacted with suitable aromatic aldehydes in order to prepare their respective diSchiff bases. These compounds were then reduced to give the corresponding tetrahydrodiSchiff bases, which were low melting in nature. Finally, these derivatives were condensed with different aromatic aldehydes to give the desired tetrahydroimidazoles. The structures of all these compounds were established on the basis of spectral data. These novel tetrahydroimidazoles showed promising anti-inflammatory and analgesic activity. The compounds were also screened for their anti-bacterial property against Staphylococcus aureus and Escherichia coli. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

  DOI：

  10.1016/s0223-5234(01)01256-9
• 作为产物：
  描述：

  邻甲氧基苯甲醛 在 sodium tetrahydroborate 作用下， 以 乙醇 、 甲苯 为溶剂， 生成 N,N'-Bis-(2-methoxy-benzyl)-ethylendiamin
  参考文献：
  名称：

  Chemosensor activity of 2-(anthracen-9-yl)-substituted imidazolidines and hexahydropyrimidines

  摘要：

  A number of 2-(anthracen-9-yl)-substituted imidazolidines and hexahydropyrimidines were synthesized by reaction of N,N'-bis[aryl(hetaryl)methyl]ethylene-1,2-diamines and N,N'-bis[aryl(hetaryl)methyl]propane-1,3-diamines with anthracene-9-carbaldehyde. The obtained compounds showed chemosensor activity toward Cd2+, Cu2+, and Hg2+ ions.

  DOI：

  10.1134/s1070428012010162

文献信息

• Comparative study of ring-opening polymerization of <scp>l</scp>-lactide and ε-caprolactone using zirconium hexadentate bis(aminophenolate) complexes as catalysts
  作者：Hsiu-Wei Ou、Michael Y. Chiang、Jaya Kishore Vandavasi、Wei-Yi Lu、Yen-Jen Chen、Hsi-Ching Tseng、Yi-Chun Lai、Hsuan-Ying Chen

  DOI：10.1039/c4ra13236j

  日期：——

  complexes as catalysts for the ring opening polymerization of L-lactide (LA) and ε-caprolactone (CL) were investigated. Ligands bearing various chelating groups have a profound influence on the catalysis results. Among them, the thiophen-2-yl methyl group showed the greatest activity while the pyridine-2-yl methyl group showed the worst performance with regard to the rate of CL polymerization. However

  研究了一系列的双（氨基酚酸）锆配合物，用于L-丙交酯（LA）和ε-己内酯（CL）的开环聚合。带有各种螯合基团的配体对催化结果有深远的影响。其中，就CL聚合速度而言，噻吩-2-基甲基表现出最大的活性，而吡啶-2-基甲基表现出最差的性能。然而，LA聚合速率的趋势相反。动力学结果表明对[CL]和[LA]具有一阶依赖性。但是，催化剂浓度的顺序不同。聚合反应依赖于[ L OMe Zr（OBn）2CL的]，但对LA的[ L OMe Zr（OBn）2 ]具有一阶依赖性。
• Crosslinkers for improving stability of polyurethane foams
  申请人：Vedage Gamini Ananda

  公开号：US20080090922A1

  公开（公告）日：2008-04-17

  A composition for making a polyurethane foam includes a non-fugitive tertiary amine urethane catalyst and an alkylated polyamine crosslinking additives. Foams prepared from the reaction of a polyol and an organic isocyanate in the presence of these ingredients show improved resistance to deterioration of physical properties upon humid aging.

  一种制备聚氨酯泡沫的配方包括非挥发性三级胺脲催化剂和烷基化聚胺交联添加剂。在这些成分的存在下，聚醚和有机异氰酸酯反应制备的泡沫在湿度老化时显示出改善的物理性能耐久性。
• Catalytic improvement of titanium complexes bearing bis(aminophenolate) in ring-opening polymerization of l -lactide and ɛ-caprolactone
  作者：Hsiu-Wei Ou、Hsing-Yin Chen、His-Ching Tseng、Mon-Wei Hsiao、Yu-Lun Chang、Nai-Yuan Jheng、Yi-Chun Lai、Tzung-Yu Shih、Yu-Ting Lin、Hsuan-Ying Chen

  DOI：10.1016/j.molcata.2014.07.003

  日期：2014.11

  This study synthesized and examined a series of titanium aminophenoxide complexes as catalysts for the ring-opening polymerization of L-lactide and epsilon-caprolactone. These Ti complexes are more active for LA than for CL. The interaction between coordinating atoms of the ligands and the central metal ions has a considerable influence on the resulting catalyses. The complex with thiophenyl groups demonstrated the highest catalytic activity, due to the lability of thiophenyl groups. Rapid changes between association and dissociation can be used to tune the electronic density of Ti in order to avoid contending with the coordination of L-lactide and epsilon-caprolactone to increase activity. In addition, kinetic results indicate a first-order dependency on [(LTi)-Ti-OMe((OPr)-Pr-i)(2)] and a first-order dependency on [CL] and [LA] respectively. (C) 2014 Elsevier B.V. All rights reserved.
• US8552078B2
  申请人：——

  公开号：US8552078B2

  公开（公告）日：2013-10-08
• Synthesis of novel tetrahydroimidazole derivatives and studies for their biological properties
  作者：Vibha Sharma、M.S.Y Khan

  DOI：10.1016/s0223-5234(01)01256-9

  日期：2001.8

  Ethylenediamine was reacted with suitable aromatic aldehydes in order to prepare their respective diSchiff bases. These compounds were then reduced to give the corresponding tetrahydrodiSchiff bases, which were low melting in nature. Finally, these derivatives were condensed with different aromatic aldehydes to give the desired tetrahydroimidazoles. The structures of all these compounds were established on the basis of spectral data. These novel tetrahydroimidazoles showed promising anti-inflammatory and analgesic activity. The compounds were also screened for their anti-bacterial property against Staphylococcus aureus and Escherichia coli. (C) 2001 Editions scientifiques et medicales Elsevier SAS.