In Situ Generated Cetyltrimethylammonium Bisulphate in Choline Chloride–Urea Deep Eutectic Solvent: A Novel Catalytic System for One Pot Synthesis of 1,3,4-Oxadiazole
Cetyltrimethylammonium bisulphate ([CTA]HSO4) catalysed onepotsynthesis of 2,5-disubstituted-1,3,4-oxadiazoles from carboxylic acid and acid hydrazide in biodegradable deepeutecticsolvent is investigated. [CTA]HSO4 is generated in situ from cetyltrimethylammonium peroxodisulphate. Cyclization of diacylhydrazide using [CTA]HSO4 gives best alternative to traditional dehydration agents. Its remarkable