di(n-decyl)methylamine | 3241-26-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: di(n-decyl)methylamine
• 英文别名: 1-decylundecylamine；henicosan-11-amine；didecylmethyl amine；didecylmethylamine
• CAS: 3241-26-7
• 化学式: C₂₁H₄₅N
• 分子量: 311.595
• InChiKey: GYVLVZDSMHALQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.4
• 重原子数：
  22
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  di(n-decyl)methylamine 在 甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 9.0h， 生成 4-(2-Carboxyethyl)-4-(1-decylundecylcarbamoylamino)heptanedioic acid
  参考文献：
  名称：

  Synthesis and antimicrobial activity of symmetrical two-tailed dendritic tricarboxylato amphiphiles

  摘要：

  Two series of water-soluble, symmetrical two-tailed homologous dendritic amphiphiles-R2NCONHC((CH2)(2)COOH)(3), 2(n,n), and R2CHNHCONHC((CH2))(2)COOH)(3), 3(n,n), where R = n-CnH2n+1-were synthesized and compared to R"NHCONHC((CH2)(2)CoOH)(3), 1(n), R" = n-CnH2n+1, to determine whether antimicrobial activity was influenced by total or individual alkyl chain lengths, and whether antimicrobial activity depends on hydrophobicity or tail topology (one or two). In a broad screen of 11 microorganisms, 2(n,n) and 3(n,n) generally displayed higher minimal inhibitory concentrations (MICs) than I(n) against growth as measured by broth microdilution assays. Chain-length specificity was observed against Candida albicans as 1(16), 2(8,8), and 3(8,8) showed the lowest MIC in their respective series. The one case where two-tailed compounds displayed the lowest MICs-3(10,10), 15 mu M; 3(11,11), 7.2 mu M; and 3(12,12), 6.9 mu M-was against Cryptococcus neoformans. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2007.03.017
• 作为产物：
  描述：

  癸基溴 在 palladium on activated charcoal sodium azide 、 氢气 、 碘 、 magnesium 、 三乙胺 作用下， 以 四氢呋喃 、 正己烷 、 N,N-二甲基甲酰胺 为溶剂， 20.0~85.0 ℃ 、427.48 kPa 条件下， 反应 79.25h， 生成 di(n-decyl)methylamine
  参考文献：
  名称：

  Synthesis and antimicrobial activity of symmetrical two-tailed dendritic tricarboxylato amphiphiles

  摘要：

  Two series of water-soluble, symmetrical two-tailed homologous dendritic amphiphiles-R2NCONHC((CH2)(2)COOH)(3), 2(n,n), and R2CHNHCONHC((CH2))(2)COOH)(3), 3(n,n), where R = n-CnH2n+1-were synthesized and compared to R"NHCONHC((CH2)(2)CoOH)(3), 1(n), R" = n-CnH2n+1, to determine whether antimicrobial activity was influenced by total or individual alkyl chain lengths, and whether antimicrobial activity depends on hydrophobicity or tail topology (one or two). In a broad screen of 11 microorganisms, 2(n,n) and 3(n,n) generally displayed higher minimal inhibitory concentrations (MICs) than I(n) against growth as measured by broth microdilution assays. Chain-length specificity was observed against Candida albicans as 1(16), 2(8,8), and 3(8,8) showed the lowest MIC in their respective series. The one case where two-tailed compounds displayed the lowest MICs-3(10,10), 15 mu M; 3(11,11), 7.2 mu M; and 3(12,12), 6.9 mu M-was against Cryptococcus neoformans. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmc.2007.03.017

文献信息

• [EN] COPPER CONTAINING CATALYST FOR PREPARATION OF ALIPHATIC AMINES<br/>[FR] CATALYSEUR CONTENANT DU CUIVRE POUR LA PRÉPARATION D'AMINES ALIPHATIQUES
  申请人：RHODIA OPERATIONS

  公开号：WO2017132937A1

  公开（公告）日：2017-08-10

  Provided is a process of reacting an aliphatic alcohol with an aminating agent for obtaining an aliphatic amine, wherein the reaction is carried out in a catalyst comprising from 68wt% to 100wt% of a copper oxide and from 0wt% to 0.1wt% of a metal co-catalyst, and optionally from 0wt% to 32wt% of a catalyst support, weight percentage is based on the total weight of the catalyst.

  提供了一种通过将脂肪族醇与氨化剂反应以获得脂肪族胺的过程，其中反应在一个催化剂中进行，该催化剂包含68wt%至100wt%的氧化铜和0wt%至0.1wt%的金属协同催化剂，并且可选地包含0wt%至32wt%的催化剂载体，重量百分比基于催化剂的总重量。
• [EN] OXIDATION OF 2-MERCAPTOETHANOL<br/>[FR] OXYDATION DU 2-MERCAPTOÉTHANOL
  申请人：BASF SE

  公开号：WO2015086565A1

  公开（公告）日：2015-06-18

  The present invention relates to a process for the preparation of bis-(2-hydroxyethyl)-disulfide by oxidizing 2-mercaptoethanol with oxygen in a reaction mixture comprising at least one ho- mogeneously distributed iron comprising salt or complex as catalyst and at least one tertiary amine, to bis-(2-hydroxyethyl)-disulfide, obtainable with the process, and to the use of this bis- (2-hydroxyethyl)-disulfide as intermediate in the manufacture of chemical compounds, such as lubricant additives and in the tertiary oil recovery.

  本发明涉及一种制备双-(2-羟乙基)-二硫化物的方法，该方法通过将2-巯基乙醇与氧气在反应混合物中氧化，其中该混合物包括至少一种均匀分布的铁盐或配合物作为催化剂和至少一种三级胺，得到的产物为双-(2-羟乙基)-二硫化物。本发明还涉及将该双-(2-羟乙基)-二硫化物作为化学化合物的中间体用于制造润滑剂添加剂和三级油回收等方面的用途。
• 3-(Trimethoxysilyl) propyldidecylmethyl ammonium salts and method of
  申请人：——

  公开号：US04394378A1

  公开（公告）日：1983-07-19

  The growth of bacteria, fungi or the like is inhibited by contacting such microorganisms with an effective amount of certain silyl quaternary ammonium salts, e.g., 3-(trimethoxysilyl) propyldidecylmethyl ammonium chloride.

  接触一定量的特定硅基季铵盐，例如3-（三甲氧基硅基）丙基十二烷基甲基铵盐，可以抑制细菌、真菌等微生物的生长。
• Amine oxide process
  申请人：ETHYL CORPORATION

  公开号：EP0356918A1

  公开（公告）日：1990-03-07

  Amine oxides which have decreased levels of nitros­amines are made by reacting tert-amines with hydrogen peroxide in the presence of titanium metal. Addition of carbon dioxide to the process results in a substantially nitrosamine-free amine oxide.

  通过在钛金属存在下，将三级胺与过氧化氢反应，可以制得含有较少亚硝胺的胺氧化物。在该过程中加入二氧化碳可以使胺氧化物基本不含亚硝胺。
• Process for the preparation of butyrolactones
  申请人：Lonza AG

  公开号：EP1911752A1

  公开（公告）日：2008-04-16

  The present invention relates to a process for the preparation of γ-butyrolactones.

  本发明涉及一种制备γ-丁内酯的方法。