2-[10-[4-[10-(1,3-Dioxoisoindol-2-yl)oxydecoxy]-2,5-diiodophenoxy]decoxy]isoindole-1,3-dione | 475265-37-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 英文名称: 2-[10-[4-[10-(1,3-Dioxoisoindol-2-yl)oxydecoxy]-2,5-diiodophenoxy]decoxy]isoindole-1,3-dione
• CAS: 475265-37-3
• 化学式: C₄₂H₅₀I₂N₂O₈
• 分子量: 964.677
• InChiKey: XUGCURKVIIYNEP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.8
• 重原子数：
  54
• 可旋转键数：
  26
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  112
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  1,10-二溴癸烷 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.5h， 生成 2-[10-[4-[10-(1,3-Dioxoisoindol-2-yl)oxydecoxy]-2,5-diiodophenoxy]decoxy]isoindole-1,3-dione
  参考文献：
  名称：

  A Novel Layer-by-Layer Approach to Immobilization of Polymers and Nanoclusters

  摘要：

  This paper reports a simple method for the multilayer immobilization of conjugated polymers, gold nanoparticles on solid supports. Poly(phenyenevinylene) functionalized with aldehyde and aminooxy groups was chemoselectively immobilized onto both glass and gold substrates via layer-by-layer deposition. The physical properties of the thin films were characterized by grazing angle IR, TM-AFM, fluorescence, and UV-visible spectroscopy. This methodology was also successfully applied to prepare polymer/gold nanocluster alternating multilayers. The results show that this methodology provides a general route for preparing robust and functionalizable multilayer films on solid substrates with molecular-level thickness control.

  DOI：

  10.1021/ja026159o

文献信息

• Functional Polymers for Layer-by-Layer Construction of Multilayers via Chemoselective Immobilization
  作者：Dong-Chan Lee、Bong-Jun Chang、Gustavo M. Morales、Young Ah Jang、Man-Kit Ng、Stephen T. Heller、Luping Yu

  DOI：10.1021/ma0356360

  日期：2004.3.1

  This paper reports detailed synthesis and characterization of polymers with functional groups for chemoselective immobilization. Various types of 1,4-diiodo-2,5-dialkoxybenzene monomers containing hydrophobic and hydrophilic groups with chemoselective functional group pairs were synthesized and copolymerized with 1,2-bis(4-vinylphenyl)ethane by using Heck coupling reaction. It was found that polymers with aldehyde and oxyamine pairs can easily be immobilized layer-by-layer while polymers with ketone functionalities did not afford multilayer deposition. The reproducible deposition process was monitored by UV/vis spectroscopy. Grazing angle reflection-absorption (GARA) FT-IR spectroscopic study confirmed that the multilayer assembly is driven by oxime bond formation. The experimental thickness of each layer was found to be 20 +/- 1 Angstrom by ellipsometry, somewhat shorter than that of extended side groups estimated by theoretical calculations. Tapping mode atomic force microscopy showed that the polymer multilayer with chemoselective ligation has the ability to patch up surface defects and provide smooth surface platform for further functionalization.