2-(7-溴-9,9-二己基-9H-芴-2-基)-4,4,5,5-四甲基-1,3,2-二氧硼戊烷 | 1048037-36-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 中文名称: 2-(7-溴-9,9-二己基-9H-芴-2-基)-4,4,5,5-四甲基-1,3,2-二氧硼戊烷
• 英文名称: 2-(7-bromo-9,9-dihexyl-9H-fluoren-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• 英文别名: 2-(7-bromo-9,9-dihexylfluoren-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• CAS: 1048037-36-0
• 化学式: C₃₁H₄₄BBrO₂
• 分子量: 539.404
• InChiKey: YJKNICCJRZRBGV-UHFFFAOYSA-N

物化性质

• 沸点：
  595.5±43.0 °C(Predicted)
• 密度：
  1.15±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.96
• 重原子数：
  35
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险性防范说明：
  P264,P280,P302+P352,P337+P313,P305+P351+P338,P362+P364,P332+P313
• 危险性描述：
  H315,H319

反应信息

• 作为反应物：
  描述：

  2-(7-溴-9,9-二己基-9H-芴-2-基)-4,4,5,5-四甲基-1,3,2-二氧硼戊烷 在 bis-triphenylphosphine-palladium(II) chloride 、 正丁基锂 、 sodium carbonate 作用下， 以 四氢呋喃 、 乙醇 、 水 、 甲苯 为溶剂， 生成 9,9,9',9'-tetrahexylbifluoren-2-ylboronic acid
  参考文献：
  名称：

  Photo- and Electroluminescence from Organoplatinum(II) Complexes Bearing Oligofluorene-Based Cyclometalated Ligands

  摘要：

  To develop phosphorescent materials for organic light-emitting diodes (OLEDs), novel organoplatinum(II) complexes bearing oligofluorene-based cyclometalated ligands were synthesized. These materials exhibited intense reddish orange photoluminescence (PL) and thus were applied as emitting dopants to OLEDs. The fabricated OLEDs showed electroluminescence identical to PL of the corresponding dopants. A non-doped device was also successfully fabricated using the developed complex as an emitting layer.

  DOI：

  10.1080/15421406.2015.1095857
• 作为产物：
  描述：

  异丙醇频哪醇硼酸酯 、 9,9-二己基-2,7-二溴代芴 在 正丁基锂 作用下， 生成 2-(7-溴-9,9-二己基-9H-芴-2-基)-4,4,5,5-四甲基-1,3,2-二氧硼戊烷
  参考文献：
  名称：

  通过顺序点击耦合的药物传递和细胞成像合成热敏共轭三嵌段共聚物。

  摘要：

  出色的发光片段和生物相关信号响应部分的完美结合可以产生先进的聚合物输送系统，同时具有相对于癌症治疗学而言有利的诊断和治疗功能。尽管已经广泛开发了基于荧光聚芴（PF）或热响应性聚（N-异丙基丙烯酰胺）（PNIPAAm）的聚合物输送系统，但由PF嵌段，PNIPAAm序列和亲水部分组成的三元聚合物配方的制备仍然很少由于可能难以整合用于聚合物合成的不同合成策略的困难，因此进行了探索。为此，在本文中我们报道了基于PF和PNIPAAm的两亲三嵌段共聚物PF 11的设计和可控合成。- b -PNIPAAm 120 - b -聚（低聚（乙二醇）单甲醚甲基丙烯酸酯）17（PF 11 - b -PNIPAAm 120 - b -POEGMA 17），通过铃木耦合生成的PF与原子转移自由基聚合（ATRP）生成的PNIPAAm和POEGMA之间的顺序点击耦合策略，具有明确定义的结构。所制备的三嵌段共聚物可以自组装

  DOI：

  10.1021/acsbiomaterials.9b00664

文献信息

• Controlled Pd(0)/<i>t</i>-Bu₃P-Catalyzed Suzuki Cross-Coupling Polymerization of AB-Type Monomers with PhPd(<i>t</i>-Bu₃P)I or Pd₂(dba)₃/<i>t</i>-Bu₃P/ArI as the Initiator
  作者：Hong-Hai Zhang、Chun-Hui Xing、Qiao-Sheng Hu

  DOI：10.1021/ja302745t

  日期：2012.8.15

  Controlled Pd(0)/t-Bu3P-catalyzed Suzuki cross-coupling polymerizations of AB-type monomers via the chain-growth mechanism with an ArPd(t-Bu3P)I complex as the initiator are described. ArPd(t-Bu3P)I complexes, either prepurified or generated in situ from Pd-2(dba)(3)/t-Bu3P/ArI (dba = dibenzylideneacetone) without separation/purification, were found to be efficient initiators in general for the controlled Suzuki cross-coupling polymerization, with narrow polydispersity indexes (PDIs) of 1.13-1.35 being observed. The Pd-2(dba)(3)/t-Bu3P/p-BrC6H4I combination was identified as a highly robust initiator system, with PDIs of <= 1.20 in general and as low as 1.13 being obtained. Higher number-average molecular weights (M-n) were achieved without a significant increase in the PDI (from 1.14 for a polymer with a M-n = 9500 to 1.20 for a polymer with M-n = 31 400) by using a smaller amount of the Pd-2(dba)(3)/t-Bu3P/p-BrC6H4I initiator in the polymerization.
• Photo- and Electroluminescence from Organoplatinum(II) Complexes Bearing Oligofluorene-Based Cyclometalated Ligands
  作者：Shigeyuki Yagi、Tatsuya Shigehiro、Tomonari Takata、Takeshi Maeda、Hiroyuki Nakazumi

  DOI：10.1080/15421406.2015.1095857

  日期：2015.11.2

  To develop phosphorescent materials for organic light-emitting diodes (OLEDs), novel organoplatinum(II) complexes bearing oligofluorene-based cyclometalated ligands were synthesized. These materials exhibited intense reddish orange photoluminescence (PL) and thus were applied as emitting dopants to OLEDs. The fabricated OLEDs showed electroluminescence identical to PL of the corresponding dopants. A non-doped device was also successfully fabricated using the developed complex as an emitting layer.
• Synthesis of Thermosensitive Conjugated Triblock Copolymers by Sequential Click Couplings for Drug Delivery and Cell Imaging
  作者：Kaicheng Deng、Xuezhi Zhao、Fangjun Liu、Jinlei Peng、Chao Meng、Yupeng Huang、Liwei Ma、Cong Chang、Hua Wei

  DOI：10.1021/acsbiomaterials.9b00664

  日期：2019.7.8

  and PNIPAAm-based amphiphilic triblock copolymer, PF11-b-PNIPAAm120-b-poly(oligo(ethylene glycol) monomethyl ether methacrylate)17 (PF11-b-PNIPAAm120-b-POEGMA17), with a well-defined structure by a strategy of sequential click couplings between Suzuki-coupling-generated PF and atom-transfer radical polymerization (ATRP)-produced PNIPAAm and POEGMA. The as-prepared triblock copolymers can self-assemble

  出色的发光片段和生物相关信号响应部分的完美结合可以产生先进的聚合物输送系统，同时具有相对于癌症治疗学而言有利的诊断和治疗功能。尽管已经广泛开发了基于荧光聚芴（PF）或热响应性聚（N-异丙基丙烯酰胺）（PNIPAAm）的聚合物输送系统，但由PF嵌段，PNIPAAm序列和亲水部分组成的三元聚合物配方的制备仍然很少由于可能难以整合用于聚合物合成的不同合成策略的困难，因此进行了探索。为此，在本文中我们报道了基于PF和PNIPAAm的两亲三嵌段共聚物PF 11的设计和可控合成。- b -PNIPAAm 120 - b -聚（低聚（乙二醇）单甲醚甲基丙烯酸酯）17（PF 11 - b -PNIPAAm 120 - b -POEGMA 17），通过铃木耦合生成的PF与原子转移自由基聚合（ATRP）生成的PNIPAAm和POEGMA之间的顺序点击耦合策略，具有明确定义的结构。所制备的三嵌段共聚物可以自组装