3-(5-p-chlorophenyl-2-furyl)propenal | 129626-60-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(5-p-chlorophenyl-2-furyl)propenal
• 英文别名: (E)-3-[5-(4-chlorophenyl)furan-2-yl]prop-2-enal
• CAS: 129626-60-4
• 化学式: C₁₃H₉ClO₂
• 分子量: 232.666
• InChiKey: AVYJFYQOHVMSQV-OWOJBTEDSA-N

物化性质

• 熔点：
  121-122 °C(Solv: ethanol (64-17-5))
• 沸点：
  387.5±37.0 °C(Predicted)
• 密度：
  1.239±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  30.2
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-(5-p-chlorophenyl-2-furyl)propenal 、 2-氨基苯硫醇 在 吡啶 作用下， 反应 0.5h， 以89%的产率得到1-(5-p-chlorophenyl-2-furyl)-2-(2-benzothiazolyl)ethene
  参考文献：
  名称：

  Synthesis and absorption spectral properties of substituted phenylfurylbenzothiazoles and their vinylogues

  摘要：

  A number of substituted 2-(5-aryl-2-furyl)benzothiazoles and their vinylogues were synthesized from corresponding 5-arylfurfurals by convenient methods. The yields of products and their UV/Vis spectroscopic properties are substituent-dependent.

  DOI：

  10.1007/bf00818165
• 作为产物：
  描述：

  反-3-(2-呋喃基)丙烯醛 、 对氯苯胺 在 盐酸 、 sodium nitrite 作用下， 生成 3-(5-p-chlorophenyl-2-furyl)propenal
  参考文献：
  名称：

  Obushak, N. D.; Ganushchak, N. I.; Lesyuk, A. I., Journal of Organic Chemistry USSR (English Translation), 1990, vol. 26, # 4, p. 748 - 753

  摘要：

  DOI：

文献信息

• 1,5-Dideoxy-1,5-imino-D-glucitol Compounds
  申请人：Lin Chun-Hung

  公开号：US20100113519A1

  公开（公告）日：2010-05-06

  1,5-Dideoxy-1,5-imino-D-glucitol compounds as shown in the specification. Also disclosed is a method of treating a hexosaminidase-associated disease.

  规范中显示的1,5-二去氧-1,5-亚胺-D-葡萄糖醇化合物。还公开了一种治疗己糖氨基酸酶相关疾病的方法。
• Bi-functional complexes and methods for making and using such complexes
  申请人：Gouliaev Alex Haahr

  公开号：US11225655B2

  公开（公告）日：2022-01-18

  The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

  本发明涉及一种合成双功能复合物的方法，该复合物包括分子部分和识别分子部分的识别寡核苷酸部分。根据本发明的合成方法的一部分优选在一种或多种有机溶剂中进行，此时包含可选保护标签或寡核苷酸标识符的新生双功能复合物与固体支持物相连接，合成方法的另一部分优选在适合于将寡核苷酸标签酶加到溶液中的新生双功能复合物的条件下进行。
• OBUSHAK, N. D.;GANUSHCHAK, N. I.;LESYUK, A. I.;DZIKOVSKAYA, L. M.;KISILIT+, ZH. ORGAN. XIMII, 26,(1990) N, S. 873-880
  作者：OBUSHAK, N. D.、GANUSHCHAK, N. I.、LESYUK, A. I.、DZIKOVSKAYA, L. M.、KISILIT+

  DOI：——

  日期：——
• BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
  申请人：Nuevolution A/S

  公开号：EP2558577A1

  公开（公告）日：2013-02-20
• BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES
  申请人：Gouliaev Alex Haahr

  公开号：US20130281324A1

  公开（公告）日：2013-10-24

  The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.