4,4-diethyl-imidazolidine-2-thione | 13385-44-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 4,4-diethyl-imidazolidine-2-thione
• 英文别名: 4,4-Diethyl-2-imidazolidinethione；4,4-diethylimidazolidine-2-thione
• CAS: 13385-44-9
• 化学式: C₇H₁₄N₂S
• 分子量: 158.268
• InChiKey: HMOWVRVERJXXER-UHFFFAOYSA-N

物化性质

• 熔点：
  108 °C
• 沸点：
  206.0±23.0 °C(Predicted)
• 密度：
  1.07±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  56.2
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  二硫化碳 、 2-ethylbutane-1,2-diamine 生成 4,4-diethyl-imidazolidine-2-thione
  参考文献：
  名称：

  Robbe; Fernandez; Dubief, European Journal of Medicinal Chemistry, 1982, vol. 17, # 3, p. 235 - 243

  摘要：

  DOI：

文献信息

• CURABLE COMPOSITION
  申请人：Kuraray Noritake Dental Inc.

  公开号：EP2979681A1

  公开（公告）日：2016-02-03

  The present invention provides a novel curable composition in which a reaction is caused to occur between a hydroperoxide and a thiourea compound to initiate polymerization of a radical polymerizable monomer and which has excellent adhesive properties, moderate curability, and excellent long-term storage stability. The present invention relates to a curable composition (A) containing: a radical polymerizable monomer (a1) having no acidic group; a hydroperoxide compound (a2); and at least one cyclic thiourea compound (a3) selected from the group consisting of a substituted ethylenethiourea compound (a3-1), a substituted propylenethiourea compound (a3-2), and a substituted butylenethiourea compound (a3-3) each having a specific structure with a cyclic structure moiety into which a substituent is introduced.

  本发明提供了一种新型可固化组合物，在该组合物中，过氧化氢和硫脲化合物发生反应，引发可自由基聚合单体的聚合，该组合物具有优异的粘合性、适度的固化性和优异的长期储存稳定性。本发明涉及一种可固化组合物 (A)，该组合物包含：不含酸性基团的可自由基聚合单体 (a1)；过氧化氢化合物 (a2)；以及至少一种环状硫脲化合物 (a3)，该环状硫脲化合物选自由取代的乙烯基硫脲化合物 (a3-1)、取代的丙烯基硫脲化合物 (a3-2) 和取代的丁烯基硫脲化合物 (a3-3) 组成的组，每种环状硫脲化合物都具有特定结构，其环状结构分子中引入了一个取代基。
• DENTAL ADHESIVE MATERIAL KIT
  申请人：Kuraray Noritake Dental Inc.

  公开号：EP3391871A1

  公开（公告）日：2018-10-24

  The present invention provides a dental adhesive material kit excellent in storage stability of the materials and exhibiting excellent bond durability to dentin by photopolymerization. The present invention is a dental adhesive material kit comprising a dental aqueous adhesive composition (A) and a dental curable composition (B), wherein: the dental aqueous adhesive composition (A) comprises a (meth)acrylic polymerizable monomer (a) containing an acid group, a vanadium compound (b), water (c), a (meth)acrylic polymerizable monomer (d) containing an amino group, and a polymerization inhibitor (i); the content of the polymerization inhibitor (i) is 25 to 1000 parts by weight per 100 parts by weight of the vanadium compound (b); and the dental curable composition (B) comprises a (meth)acrylic polymerizable monomer (e) containing no acid group, a hydroperoxide (f), a photopolymerization initiator (g), and a filler (h) and does not comprise a thiourea compound.

  本发明提供了一种牙科粘合剂材料包，材料的储存稳定性极佳，通过光聚合作用与牙本质的粘合耐久性极佳。本发明是一种牙科粘接材料套件，包括牙科水性粘接剂组合物（A）和牙科固化组合物（B），其中牙科水性粘合剂组合物（A）包括含有酸基的(甲基)丙烯酸可聚合单体（a）、钒化合物（b）、水（c）、含有氨基的(甲基)丙烯酸可聚合单体（d）和聚合抑制剂（i）；聚合抑制剂 (i) 的含量为每 100 重量份钒化合物 (b) 25 至 1000 重量份；牙科固化组合物 (B) 包括不含酸基的（甲基）丙烯酸可聚合单体 (e)、过氧化氢 (f)、光聚合引发剂 (g) 和填料 (h)，且不包括硫脲化合物。
• DENTAL COMPOSITION CONTAINING PLATINUM NANOPARTICLES
  申请人：Kuraray Noritake Dental Inc.

  公开号：EP3725288A1

  公开（公告）日：2020-10-21

  The present invention provides a dental composition that exhibits excellent long-lasting antibacterial activity even as a cured product, and that excels in aesthetic quality with no discoloration occurring in water or in hydrogen sulfide. The present invention relates to a dental composition comprising a platinum nanoparticle (a) uncoated with a colloidal protective material.

  本发明提供了一种牙科组合物，该组合物即使作为固化产品也具有出色的长效抗菌活性，并且在水中或硫化氢中不会变色，具有出色的美观性。本发明涉及一种牙科组合物，该组合物包含未涂覆胶体保护材料的铂纳米粒子（a）。
• Dental adhesive material kit
  申请人：KURARAY NORITAKE DENTAL INC.

  公开号：US10478385B2

  公开（公告）日：2019-11-19

  The present invention provides a dental adhesive material kit excellent in storage stability of the materials and exhibiting excellent bond durability to dentin by photopolymerization. The present invention is a dental adhesive material kit comprising a dental aqueous adhesive composition (A) and a dental curable composition (B), wherein: the dental aqueous adhesive composition (A) comprises a (meth)acrylic polymerizable monomer (a) containing an acid group, a vanadium compound (b), water (c), a (meth)acrylic polymerizable monomer (d) containing an amino group, and a polymerization inhibitor (i); the content of the polymerization inhibitor (i) is 25 to 1000 parts by weight per 100 parts by weight of the vanadium compound (b); and the dental curable composition (B) comprises a (meth)acrylic polymerizable monomer (e) containing no acid group, a hydroperoxide (f), a photopolymerization initiator (g), and a filler (h) and does not comprise a thiourea compound.

  本发明提供了一种牙科粘合剂材料包，材料的储存稳定性极佳，通过光聚合作用与牙本质的粘合耐久性极佳。本发明是一种牙科粘接材料套件，包括牙科水性粘接剂组合物（A）和牙科固化组合物（B），其中牙科水性粘合剂组合物（A）包括含有酸基的(甲基)丙烯酸可聚合单体（a）、钒化合物（b）、水（c）、含有氨基的(甲基)丙烯酸可聚合单体（d）和聚合抑制剂（i）；聚合抑制剂 (i) 的含量为每 100 重量份钒化合物 (b) 25 至 1000 重量份；牙科固化组合物 (B) 包括不含酸基的（甲基）丙烯酸可聚合单体 (e)、过氧化氢 (f)、光聚合引发剂 (g) 和填料 (h)，且不包括硫脲化合物。
• Dual-curing dental compositions with high stability
  申请人：James R. Glidewell Dental Ceramics, Inc.

  公开号：US11020324B2

  公开（公告）日：2021-06-01

  Two-part dual-curing dental compositions containing a hydroperoxide, a thiourea derivative and an acetylacetonate salt as redox radical initiator system, are provided. The dental compositions may contain an acidic monomer for use as a self-adhesive cement. The dental compositions possess enhanced shelf-life stability for working/setting time, bonding strength, color stability, slump, flexural strength/modulus, and when kept at 50° C. for more than 16 weeks.

  双组分双固化牙科组合物含有过氧化氢、硫脲衍生物和乙酰丙酮盐作为氧化还原自由基引发剂体系。这种牙科组合物可能含有一种酸性单体，可用作自粘性粘合剂。当在 50° C 下保存 16 周以上时，牙科组合物在工作/凝固时间、粘接强度、颜色稳定性、坍落度、抗弯强度/模量方面的货架期稳定性均有所提高。