(2,3-Dihydrobenzo[f]chromen-1-ylideneamino)urea | 202605-56-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 萘并吡喃类
• 英文名称: (2,3-Dihydrobenzo[f]chromen-1-ylideneamino)urea
• CAS: 202605-56-9
• 化学式: C₁₄H₁₃N₃O₂
• 分子量: 255.276
• InChiKey: IYXQPKFWUQQYPC-UHFFFAOYSA-N

物化性质

• 熔点：
  248-250 °C
• 密度：
  1.39±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (2,3-Dihydrobenzo[f]chromen-1-ylideneamino)urea 在 selenium(IV) oxide 作用下， 以 溶剂黄146 为溶剂， 反应 12.0h， 以90%的产率得到4H-naphtho[1',2'-5,6]pyrano[3,4-d](1,2,3)selenadiazole
  参考文献：
  名称：

  Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1′,2′–5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives

  摘要：

  Synthesis of new heterocyclic compounds 3a-e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a-e have shown moderate anti-bacterial activity against some gram-positive and grain-negative bacterias. (C) 2008 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2008.01.026
• 作为产物：
  描述：

  2,3-二氢-1H-萘并[2,1-b]吡喃-1-酮 、 盐酸氨基脲 在 sodium acetate 作用下， 以 乙醇 为溶剂， 反应 1.0h， 以95%的产率得到(2,3-Dihydrobenzo[f]chromen-1-ylideneamino)urea
  参考文献：
  名称：

  Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1′,2′–5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives

  摘要：

  Synthesis of new heterocyclic compounds 3a-e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a-e have shown moderate anti-bacterial activity against some gram-positive and grain-negative bacterias. (C) 2008 Elsevier Masson SAS. All rights reserved.

  DOI：

  10.1016/j.ejmech.2008.01.026

文献信息

• Synthesis and in vitro anti-bacterial evaluation of tetracyclic-ortho-fused 4H-naphtho[1′,2′–5,6]pyrano[3,4-d](1,2,3)selenadiazole and its derivatives
  作者：A.V. Karnik、A.M. Kulkarni、N.J. Malviya、B.R. Mourya、B.L. Jadhav

  DOI：10.1016/j.ejmech.2008.01.026

  日期：2008.11

  Synthesis of new heterocyclic compounds 3a-e containing naphthopyran and selenadiazole as the heterocyclic sub-units in the molecule is achieved using high yielding synthetic protocol. These molecules 3a-e have shown moderate anti-bacterial activity against some gram-positive and grain-negative bacterias. (C) 2008 Elsevier Masson SAS. All rights reserved.