(4-ClC6H4)3SbBr2 | 91002-41-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-ClC6H4)3SbBr2
• 英文别名: dibromo-tris(4-chlorophenyl)-λ5-stibane
• CAS: 91002-41-4
• 化学式: C₁₈H₁₂Br₂Cl₃Sb
• 分子量: 616.21
• InChiKey: LLMDVARJKORQPE-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  5.85
• 重原子数：
  24.0
• 可旋转键数：
  3.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  (4-ClC6H4)3SbBr2 、 邻苯二甲酰亚胺钠盐 生成 2-[tris(4-chlorophenyl)-(1,3-dioxoisoindol-2-yl)-λ5-stibanyl]isoindole-1,3-dione
  参考文献：
  名称：

  SINGHAL, KIRAN;RASTOGI, RAJIV;RAJ, PREM, INDIAN J. CHEM., 26,(1987) N 2, 146-150

  摘要：

  DOI：
• 作为产物：
  描述：

  氯(4-氯苯基)镁 以 乙醚 、 乙醇 为溶剂， 生成 (4-ClC6H4)3SbBr2
  参考文献：
  名称：

  Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Sb: Org.Comp.1, 1.1.1.1.7, page 87 - 96

  摘要：

  DOI：

文献信息

• Synthesis, characterization and in vitro antitumor activity of some arylantimony ferrocenylcarboxylate derivatives and the crystal structures of [C5H5FeC5H4C(CH3)CHCOO]2Sb(C6H4F-4)3 and [4-(C5H5FeC5H4)C6H4COO]2Sb(C6H4F-4)3
  作者：Lin Yu、Yong-Qiang Ma、Run-Chang Liu、Guo-Cang Wang、Jin-Shan Li、Guan-Hua Du、Juan-Juan Hu

  DOI：10.1016/j.poly.2003.12.002

  日期：2004.3

  A series of novel arylantimony ferrocenylcarboxylate derivatives with the formulae [C5H5FeC5H4C(CH3)=CHCOO](2)SbAr3 and [4-(C5H5FeC5H4)C6H4COO](2)SbAr3 (Ar=C6H5, 4-CH3C6H4, 4-ClC6H4, 4-FC6H4) were synthesized and characterized by elemental analysis, IR and H-1 NMR. The crystal structures of [C5H5FeC5H4C(CH3)=CHCOO](2)Sb(C6H4F-4)(3) and [4-(C5H5FeC5H4)C6H4COO](2)Sb(C6H4F-4)(3) were determined by X-ray diffraction. The two sets of crystal X-ray data show that the antimony atom of the former has a special six-coordinate geometry while that of the latter has a general five-coordinate geometry. Three human neoplastic cell lines (HCT-8, Bel-7402 and KB) were used to screen these compounds. The results indicate that [C5H5FeC5H4C(CH3)=CHCO2](2)Sb(C6H4Cl-4)(3) and [C5H5FeC5H4C(CH3)=CHCO2](2)Sb(C6H4F-4)(3) at 5 muM show relatively good in vitro antitumor activities. (C) 2003 Elsevier Ltd. All rights reserved.
• Synthesis, crystal structures and in vitro antitumor activities of some arylantimony derivatives of analogues of demethylcantharimide
  作者：Guo-Cang Wang、Jian Xiao、Lin Yu、Jin-Shan Li、Jing-Rong Cui、Rui-Qing Wang、Fu-Xiang Ran

  DOI：10.1016/j.jorganchem.2004.02.015

  日期：2004.5

  A series of novel aylantimony derivatives of analogues of demethylcantharimide with the formulae ArnSbL(5-n) and ArnSbL'((5-n))(LH = N-hydroxy-demethyldehydrogencantharimide, L'H = N-hydroxy-demethyleantharimide, n = 3, 4; Ar=C6H5, 4CH(3)C(6)H(4), 3-CH3C6H4, 2-CH3C6H4, 4-ClC6H4, 4-FC6H4) were synthesized and characterized by elemental analysis, IR, 1 H NMR and mass spectroscopy. The crystal structures of (C6H5)(4)SbL, (4-CH3C6H4)(3)SbL2 and (3-CHC6H4)(3)SbL'(2) were determined by X-ray diffraction. The in vitro antitumor activities of all compounds against six cancer cells are reported. (C) 2004 Elsevier B.V. All rights reserved.
• Synthesis, characterization and antitumor activity of some arylantimony triphenylgermanylpropionates and crystal structures of Ph3GeCH(Ph)CH2CO2SbPh4 and [Ph3GeCH2CH(CH3)CO2]2Sb(4-ClC6H4)3
  作者：Yongqiang Ma、Jinshan Li、Zhenai Xuan、Runchang Liu

  DOI：10.1016/s0022-328x(00)00799-3

  日期：2001.2

  A series of novel arylantimony(V) triphenylgermanylpropionates with the formula ((Ph3GeCHRCHRCO2)-C-1-C-2)(n)SbAr(5-n) (R-1 = H, Ph; R-2 =H, CH3; n = 1, 2) were synthesized and characterized by elemental analysis, IR, H-1-NMR, C-13-NMR and mass spectroscopy. The crystal structures of Ph3GeCH(Ph)CH2CO2SbPh4 and [Ph3GeCH2CH(CH3)CO2](2)Sb(4-ClC6H4)(3) were determined by X-ray diffraction. The in vitro antitumor activities of some selected compounds against five cancer cells are reported. (C) 2001 Elsevier Science B.V. All rights reserved.
• Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates
  作者：Guo-Cang Wang、Yong-Na Lu、Jian Xiao、Lin Yu、Hai-Bin Song、Jin-Shan Li、Jing-Rong Cui、Rui-Qing Wang、Fu-Xiang Ran

  DOI：10.1016/j.jorganchem.2004.09.002

  日期：2005.1

  A series of novel organoantimony arylhydroxamates with the formulae [Ar3SbL2,](-)[HNEt3](+) (LH = arylhydroxamic acid: Ar = C6H5. 4-CH3C6H4, 3-CH3C6H4, 4-ClC6H4, 4-FC6H4) and (4-CH3C6H4)(4)SbL were synthesized and characterized by elemental analysis, IR. H-1 NMR and mass spectroscopy. The crystal structures of (4-CH3C6H4)(4)SbL and [Ph3SbL2](-)[HNEt3](+) were determined by X-ray diffraction. The in vitro antitumor activities of all compounds against three human cancer cells are reported. (C) 2004 Published by Elsevier B.V..
• Harris, J. I.; Bowden, S. T.; Jones, W. J., Journal of the Chemical Society
  作者：Harris, J. I.、Bowden, S. T.、Jones, W. J.

  DOI：——

  日期：——