2,2'-dihydroxy-4,4'-dimethoxybenzophenone-5-sulfonic acid | 21927-94-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2'-dihydroxy-4,4'-dimethoxybenzophenone-5-sulfonic acid
• 英文别名: 2,2'-DIHYDROXY-4,4'-DIMETHOXY-5-SULFOBENZOPHENONE；2,2'-dihydroxy-4,4'dimethoxybenzophenone-5-sulfonic acid；2,2'-Dihydroxy-4,4'-dimethoxy-5-sulpho-benzophenone；4-hydroxy-5-(2-hydroxy-4-methoxybenzoyl)-2-methoxybenzenesulfonic acid
• CAS: 21927-94-6
• 化学式: C₁₅H₁₄O₈S
• 分子量: 354.337
• InChiKey: RPPHWBSWFASQRA-UHFFFAOYSA-N

物化性质

• 熔点：
  160-162 °C
• 密度：
  1.506±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  139
• 氢给体数：
  3
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  2,2'-二羟基-4,4'-二甲氧基二苯甲酮 在 氯磺酸 作用下， 以 苯甲酸乙酯 为溶剂， 生成 2,2'-dihydroxy-4,4'-dimethoxybenzophenone-5-sulfonic acid
  参考文献：
  名称：

  Preparation of 4-alkoxy-2-hydroxybenzophenone-5-sulfonic acids

  摘要：

  通用公式I的4-烷氧基-2-羟基苯基酮-5-磺酸的化合物，其中R.sup.1是未取代或取代的C.sub.1-C.sub.20-烷基，取代基包括卤素、氰基、羟基、C.sub.1-C.sub.20-烷氧基、C.sub.2-C.sub.20-烷氧羰基、酰氧基和/或苯基，苯基未取代或取代的基团包括C.sub.1-C.sub.4-烷基、C.sub.1-C.sub.4-烷氧基和/或卤素，R.sup.2和R.sup.3独立地为氢、卤素、C.sub.1-C.sub.12-烷基、C.sub.1-C.sub.12-烷氧基、C.sub.1-C.sub.4-卤代烷基、C.sub.3-C.sub.8-环烷基、C.sub.4-C.sub.12-环烷基烷基、氰基、羟基或羟乙基，或者为各自的苯氧基、C.sub.7-C.sub.10-苯基烷基或苯基，未取代或取代的基团包括C.sub.1-C.sub.4-烷基、C.sub.1-C.sub.4-烷氧基和/或卤素，R.sup.4为氢或磺酰基，通过将通用公式II的4-烷氧基-2-羟基苯基酮与氯磺酸在-20度至+100度C之间反应而制备，所述反应在脂肪族、环脂族和/或芳香族羧酸酯作为溶剂的新颖改进过程中进行。

  公开号：

  US05072034A1

文献信息

• Therapeutic and diagnostic ligand systems comprising transport molecule binding properties and medicaments containing the same
  申请人：——

  公开号：US20030185793A1

  公开（公告）日：2003-10-02

  The invention relates to transport molecule binding ligand compounds which comprise a therapeutically and/or diagnostically active substance and a carrier molecule-affine substance with a high association constant to the carrier molecule. The invention also relates to medicaments containing these ligand compounds and to diagnostic kits.

  这项发明涉及与载体分子结合的配体化合物，其包括具有治疗和/或诊断活性物质以及与载体分子具有高结合常数的载体分子亲和物质。该发明还涉及含有这些配体化合物的药物和诊断试剂盒。
• RESIN COMPOSITION AND MOLDED PRODUCT OBTAINED BY MOLDING THE RESIN COMPOSITION
  申请人：Shibuya Atsushi

  公开号：US20100074083A1

  公开（公告）日：2010-03-25

  Provided are a resin composition comprising 100 parts by mass of the polymer having an alicyclic structure at least in a part of a repeating structural unit and 0.05 to 5 parts by mass of a hindered amine compound having a carbon atom at a ratio of from 67% by weight to 80% by weight in the molecular structure and having a molecular weight of from 500 to 3500, a novel piperidine derivative having a piperidylaminotriazine skeleton, a molded product such as an optical component obtained by molding the resin composition, and an optical pickup device which employs the optical component.

  提供的是一种树脂组合物，包括100质量部分具有环脂环结构的聚合物和0.05至5质量部分的分子结构中至少有部分碳原子的受阻胺化合物，其分子结构中碳原子占比从67%到80%。分子量在500至3500之间，一种具有哌啶氨基三嗪骨架的新型哌啶衍生物，以及通过模压树脂组合物获得的光学元件等成型产品，以及采用该光学元件的光学拾取器件。
• EMULSION PREPARATION FOR EXTERNAL APPLICATION TO SKIN AND COSMETIC PREPARATION
  申请人：Showa Denko K.K.

  公开号：EP2238970A1

  公开（公告）日：2010-10-13

  An object of the present invention is to provide emulsified skin external preparations and cosmetics which contain a branched acyl carnitine and have excellent emulsion stability. An emulsified skin external preparation according to the present invention includes 0.01 to 10% by mass of a carnitine derivative represented by the following Formula (1) and/or a carnitine derivative salt represented by the following Formula (2), and 0.01 to 20% by mass of a nonionic surfactant. In Formula (1), R1 and R2 are each independently a C1-18 optionally branched, saturated or unsaturated aliphatic hydrocarbon group. In Formula (2), R1 and R2 are the same as in Formula (1), X- is a specific anion and Y+ is a specific cation.

  本发明的一个目的是提供含有支链酰基肉碱且具有优异乳化稳定性的乳化皮肤外用制剂和化妆品。根据本发明的乳化皮肤外用制剂包括下列式（1）所表示的肉碱衍生物和/或下列式（2）所表示的肉碱衍生物盐，以及非离子表面活性剂，其质量百分含量分别为0.01至10%和0.01至20%。在式（1）中，R1和R2各自独立地是C1-18的可选支链、饱和或不饱和脂肪烃基。在式（2）中，R1和R2与式（1）中相同，X-是特定阴离子，Y+是特定阳离子。
• Reactive monomer composition modified by a small-amount of lactones, an acrylic polyol resin, a curable resin composition, and a coating composition
  申请人：——

  公开号：US20040171867A1

  公开（公告）日：2004-09-02

  The present invention Nos. I and II relate to a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones in which a proportion of monomers having two or more continuous chains (n≧2) of lactone is less than 50% (area % by GPC) which is obtained by a ring-opening polymerization of a lactone with a hydroxyalkyl(meth)acrylate, a method for the preparation thereof, and an acrylic polyol resin using thereof, 1 (in the formula, R, R 1 , R 2 , and R 3 are independently a hydrogen or a methyl group, “j” is an integer of 2-6, xn pieces of R 4 and R 5 are independently a hydrogen atom or an alkyl group having a carbon number of 1-12, “x” is 4-7, “n” is 0 or an integer of not less than 1, and an average value of “n” in the composition is not less than 0.3 to less than 1.0). By allowing to react the composition with other ethylenic unsaturated monomer and to formulate with a commonly-used crosslinking agent and other commonly-used components, there can be obtained a well-balanced high quality finishing agent for industries, an ultraviolet ray- or electron beam-curable coating agent, a composition which can be modified for a reactive improver, etc., and an acrylic polyol resin using thereof. The present invention No. III relates to a curable resin composition containing 0.5-80 parts by weight of an acrylic polyol resin (A) obtained using a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones and 0.5-50 parts by weight of a melamine resin (B) [total of the (A) and (B) does not exceed, 100 parts by weight] as essential components. By the composition, even in a melamine-based curing system which is low in price, there can be obtained a curable-type coating composition in which an acid resistance is improved and highly well-balanced between an acid resistance and abrasion resistance, and which is also excellent in flexural resistance and adhesion in recoating. The present invention No. IV relates to a curable resin composition containing 0.5-80 parts by weight of an acrylic polyol resin (A) containing a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones as a polymerizing component and 0.5-50 parts by weight of a melamine resin (B) [total of the (A) and (B) does not exceed 100 parts by weight] as essential components. By the composition, even in a melamine-based curing system which is low in price, there can be obtained a curable-type coating composition in which an acid resistance is improved and highly well-balanced between an acid resistance and abrasion resistance. The present invention No. V relates to a curable resin composition containing 0.5-80 parts by weight of an acrylic polyol resin (A) obtained using a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones and 0.5-50 parts by weight of a polyisocyanate compound (B) [total of the (A) and (B) does not exceed 100 parts by weight] as essential components. By the composition, even in an isocyanate-based curing system, there can be obtained a curable-type coating composition in which a pot life is long and workability is improved, and which is highly well-balanced between an acid resistance and abrasion resistance, and which can provide a coating layer which is excellent also in flexural resistance and adhesion in recoating. The present invention No. VI relates to a curable resin composition containing 0.5-80 parts by weight of an acrylic polyol resin (A) obtained using a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones and 0.5-50 parts by weight of a polyisocyanate compound (B) [total of the (A) and (B) does not exceed 100 parts by weight] as essential components. By the composition, even in an isocyanate-based curing system, there can be obtained a curable-type coating composition in which a pot life is long and workability is improved, and which is highly well-balanced between an acid resistance and abrasion resistance, and which can provide a coating layer which is excellent also in flexural resistance and adhesion in recoating. The present invention No. VII relates to a thermosetting resin composition containing 2-50 parts of an acrylic polyol resin obtained using a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones and 30-80 parts of an acrylic copolymer having an alkoxysilyl group. By the composition, there can be obtained a thermosetting resin composition in which crosslinking density is elevated and hardness and abrasion resistance are improved as well as solving a problem of acid resistance and odor. The present invention No. VIII relates to a carboxylic group-contained acrylate composition (a′) modified by a small amount of lactones represented by a formula described below by allowing to react a hydroxyalkyl(meth)acrylate composition (a) modified by a small amount of lactones with a carboxylic anhydride, 2 (in the formula, R, R 1 , R 2 , and R 3 are independently a hydrogen or a methyl group, “j” is an integer of 2-6, xn pieces of R 4 and R 5 are independently a hydrogen atom or an alkyl group having a carbon number of 1-12, “x” is 4-7 , “n” is 0 or an integer of not less than 1, an average value of “n” in the composition is not less than 0.3 to less than 1.0 , R 6 is a residual group of a carboxylic acid, and “m” is an integer of 1-3), and relates to a method for the preparation thereof. By the method, there can be readily, efficiently, and economically obtained the carboxylic group-contained acrylate monomer composition modified by a small amount of lactones. The present invention No. IX relates to a curable resin composition containing 10-70 parts of an acrylic polycarboxylic resin essentially containing the carboxylic group-contained hydroxy(meth)acrylate monomer composition (a′) modified by a small amount of lactones as a polymerizing component and 0.5-80 parts of a polyepoxide. By the composition, there can be obtained a curable-type resin composition which can form a coating layer which is excellent in acid resistance, abrasion resistance, yellowing resistance, and outer appearance, and which is curable at a low temperature. The present invention No. X relates to a polyester unsaturated monomer (a″) modified by a small amount of lactones in which less than 1 mol of &egr;-caprolactone is allowed to react with 1 mol of a radically polymerizable unsaturated monomers containing carboxylic group under the presence of an acidic catalyst, and relates to a method for the preparation thereof. By the method, there can be readily and industrially prepared the monomer in a short step.

  本发明涉及一种由少量内酯修饰的羟基烷基（甲基）丙烯酸酯组合物（a），其中具有两个或多个连续链（n≥2）的内酯单体的比例小于50％（GPC的面积％），其通过羟基烷基（甲基）丙烯酸酯与内酯的开环聚合获得，以及制备方法和使用其的丙烯酸聚醇树脂。其中，在公共使用的交联剂和其他常用组分的反应下，可以获得工业上平衡良好的高质量涂料剂、紫外线或电子束固化涂料剂、可用于反应改进剂的组合物等。本发明还涉及含有0.5-80重量份羟基烷基（甲基）丙烯酸酯组合物（a）修饰的丙烯酸聚醇树脂（A）和0.5-50重量份三聚氰胺树脂（B）的可固化树脂组合物（A）和（B）的总重量不超过100重量份的可固化树脂组合物（III）。此外，还涉及含有0.5-80重量份羟基烷基（甲基）丙烯酸酯组合物（a）修饰的丙烯酸聚醇树脂（A）和0.5-50重量份聚异氰酸酯化合物（B）的可固化树脂组合物（A）和（B）的总重量不超过100重量份的可固化树脂组合物（V）和（VI）。还涉及含有羟基烷基（甲基）丙烯酸酯组合物（a）修饰的丙烯酸聚醇树脂（A）和具有烷氧基硅基团的丙烯酸共聚物的热固性树脂组合物（VII）。此外，还涉及通过使少量内酯与羟基烷基（甲基）丙烯酸酯组合物（a）在存在酸性催化剂的情况下反应而得到的含有羧基丙烯酸酯组合物（a′）的修饰物，以及含有羧基丙烯酸酯组合物（a′）和聚环氧化合物的可固化树脂组合物（IX）。最后，还涉及通过在存在酸性催化剂的情况下使少于1摩尔的ε-己内酯与含有羧基团的自由基聚合可的不饱和单体反应而得到的少量内酯修饰的聚酯不饱和单体（a″）以及其制备方法。
• METHOD FOR REDUCING SUNBURN DAMAGE IN PLANTS
  申请人：Riggs Richard

  公开号：US20120017503A1

  公开（公告）日：2012-01-26

  The present invention relates to methods, use and compositions for reducing sunburn damage in plants. More specifically, it relates to methods and compositions for controlling, preventing, or treating sunburn damage using UV filters.

  本发明涉及减少植物受晒伤害的方法、用途和组合物。更具体地说，涉及使用紫外线过滤器控制、预防或治疗晒伤损伤的方法和组合物。