2-Isobutyl-6-methyl-phenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Isobutyl-6-methyl-phenol
• 英文别名: 2-Hydroxy-1-methyl-3-isobutyl-benzol；2-Methyl-6-(2-methylpropyl)phenol
• 化学式: C₁₁H₁₆O
• 分子量: 164.247
• InChiKey: BWVHLTNCVRBWKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  6-Methyl-2-<β-methyl-allyl>-phenol 在 氢氧化钾 、 乙醇 、 铂 作用下， 生成 2-Isobutyl-6-methyl-phenol
  参考文献：
  名称：

  The Introduction of Isobutyl Groups into Phenols, Cresols and Homologous Compounds

  摘要：

  DOI：

  10.1021/ja01305a044

文献信息

• Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same
  申请人：Kim Seon Mi

  公开号：US20130137661A1

  公开（公告）日：2013-05-30

  Disclosed are compounds useful as gonadotrophin-releasing hormone (“GnRH”) receptor antagonist.

  披露了作为促性腺激素释放激素（“GnRH”）受体拮抗剂有用的化合物。
• Process For Producing Phosphonitrilic Acid Ester
  申请人：Kuwata Kotaro

  公开号：US20080091050A1

  公开（公告）日：2008-04-17

  A process for producing a cyclic and/or linear phosphonitrilic acid ester from a cyclic and/or linear phosphonitrile dichloride is provided, wherein the reaction time is shorter and the content of monochloro phosphazenes is very small. When phosphonitrile dichloride is reacted with a metal arylolate and/or a metal alcoholate in the presence of a reaction solvent, a metal arylolate and/or a metal alcoholate composed of at least two different metals having different ionization energies is used and also a specific compound is used as a catalyst.

  解决的问题：提供一种从环状和/或线性磷酸腈二氯化物制备环状和/或线性磷氮酸酯的方法，其中反应时间较短，单氯磷氮烷的含量非常小。 解决方案：当磷酸腈二氯化物与金属芳酚醇盐和/或金属醇盐在反应溶剂存在下反应时，使用由至少两种具有不同电离能的金属组成的金属芳酚醇盐和/或金属醇盐，并且还使用特定化合物作为催化剂。
• Process for producing polyphenylene oxide
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0059958A1

  公开（公告）日：1982-09-15

  A process for producing polyphenylene oxide which comprises contacting a phenolic monomer with oxygen in the presence of a catalyst composed of a manganese (II) salt and an ortho-hydroxyazo compound represented by the following formula: where A and B represent identical or different arylene ring having a valency of at least 2 and having an oxy group and an azo group directly linked to the ortho carbon atoms of the arylene ring and R represents hydrogen or lower alkyl group, or in the presence of said catalyst and an amine, in a polymerization solvent containing a base and thereby subjecting said phenolic monomer to an oxidative polymerization.

  一种生产聚苯醚的工艺，它包括在由锰（II）盐和下式代表的邻羟基偶氮化合物组成的催化剂存在下，使酚类单体与氧气接触： 式中 A 和 B 代表相同或不同的芳烯环，其价数至少为 2，并有一个氧基和一个偶氮基直接连接到芳烯环的正碳原子上，R 代表氢或低级烷基，或在所述催化剂和胺的存在下，在含有碱的聚合溶剂中，使所述酚类单体进行氧化聚合。
• Process for producing polyphenylene ethers
  申请人：MITSUBISHI PETROCHEMICAL CO., LTD.

  公开号：EP0255230A1

  公开（公告）日：1988-02-03

  A process for producing a polyphenylene ether comprises oxidatively polymerizing a phenol in an organic solvent in the presence of an oxidative polymerization catalyst, finely dispersing the resulting polyphenylene ether contained in the organic solvent in an aqueous dispersion medium containing an acid compound, and heating the aqueous dispersion to remove the solvent from the polyphenylene ether. The resulting polyphenylene ether has excellent powder properties and contains a reduced amount of catalyst residue.

  生产聚苯醚的工艺包括：在氧化聚合催化剂存在下，在有机溶剂中对苯酚进行氧化聚合；将有机溶剂中所含的聚苯醚分散在含有酸化合物的水分散介质中；加热水分散介质，从聚苯醚中除去溶剂。 得到的聚苯醚具有极佳的粉末特性，且催化剂残留量较低。
• Polyphenylene ether process and resin composition
  申请人：GENERAL ELECTRIC COMPANY

  公开号：EP0491190A2

  公开（公告）日：1992-06-24

  The invention provides a process for producing a polyphenylene ether by subjecting a 2,6-disubstituted phenol to oxidative coupling by introducing oxygen in the presence of a catalyst system which comprises a manganese compound, a chelant, a base, and an alpha,beta-unsaturated ketone, a beta-diketone, or a vinyl ether. The polyphenylene oxide produced has substantially no amine odor and more stable molecular weight, and is suitable for blending with styrenic or other resins to make thermoplastic resin blends of low odor and good physical properties.

  本发明提供了一种生产聚苯醚的工艺，其方法是在由锰化合物、螯合剂、碱和α，β-不饱和酮、β-二酮或乙烯基醚组成的催化剂体系存在下，通过引入氧气使 2，6-二取代苯酚发生氧化偶联。生产出的聚苯醚基本上没有胺味，分子量更稳定，适合与苯乙烯或其他树脂混合，制成气味小、物理性能好的热塑性树脂混合物。