1,2-bis(diphenylphosphino)ethane-bis(triphenylphosphine)nickel(0) | 54428-80-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,2-bis(diphenylphosphino)ethane-bis(triphenylphosphine)nickel(0)
• 英文别名: [1,2-bis(diphenylphosphino)ethane]bis(triphenylphosphino)nickel；Ni(pph3)dppe；2-diphenylphosphanylethyl(diphenyl)phosphane;nickel;triphenylphosphane
• CAS: 54428-80-7
• 化学式: C₆₂H₅₄NiP₄
• 分子量: 981.696
• InChiKey: IBAFMCZXBKXSTB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.14
• 重原子数：
  67
• 可旋转键数：
  10
• 环数：
  10.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,2-bis(diphenylphosphino)ethane-bis(triphenylphosphine)nickel(0) 、 (2-(4-bromophenyl)ethynyl)triisopropylsilane 以 四氢呋喃 为溶剂， 反应 44.0h， 以58%的产率得到
  参考文献：
  名称：

  Solution-Based Single Molecule Imaging of Surface-Immobilized Conjugated Polymers

  摘要：

  The photophysical behavior of conjugated polymers used in modern optoelectronic devices is strongly influenced by their structural dynamics and conformational heterogeneity, both of which are dependent on solvent properties. Single molecule studies of these polymer systems embedded in a host matrix have proven to be very powerful to investigate the fundamental fluorescent properties. However, such studies lack the possibility of examining the relationship between conformational dynamics and photophysical response in solution, which is the phase from which films for devices are deposited. By developing a synthetic strategy to incorporate a biotin moiety as a surface attachment point at one end of a polyalkylthiophene, we immobilize it, enabling us to make the first single molecule fluorescence measurements of conjugated polymers for long periods of time in solution. We identify fluctuation patterns in the fluorescence signal that can be rationalized in terms of photobleaching and stochastic transitions to reversible dark states. Moreover, by using the advantages of solution-based imaging, we demonstrate that the addition of oxygen scavengers improves optical stability by significantly decreasing the photobleaching rates.

  DOI：

  10.1021/ja311874f
• 作为产物：
  描述：

  双三苯基膦二羰基镍 以 氘代氯仿 、 氘代苯 为溶剂， 反应 2.0h， 生成 1,2-bis(diphenylphosphino)ethane-bis(triphenylphosphine)nickel(0)
  参考文献：
  名称：

  镍（0）的2-吡啶基膦和-二膦配合物，它们的反应性（包括水溶液化学性质）以及一些相关的偶合甲基碘化碘

  摘要：

  摘要Ni（CO）2L2型Ni0-二羰基（吡啶基膦）配合物的化学性质，其中L为P键结合的PPh3-npyn（n = 1-3，py = 2-吡啶基；缩写为PNx，x = 1– 3，1a–c）或L2是（P–P）螯合的py2P（CH2）2Ppy2或，是我们小组从较早的研究中进一步开发的[P–P配体分别缩写为d（py） pe和d（py）pcp]。由Ni（CO）2（PPh3）2的C6H6溶液合成配合物，并检测到Ni（CO）2（PPh3）（PNx）中间体（1a ∗ –c ∗）；X射线分析表明Ni（CO）2 [d（py）pcp]（2b）具有扭曲的四面体结构；从CDCl3溶液中的光诱导反应中分离出NiII物质[Ni2（CO）4（μ-PN2）2] Cl4。络合物2b在环境条件下通过吡啶基N原子的净双质子化作用溶于水，分离出{Ni（CO）2 [2H-d（py）pcp]} 2+为双（三氟甲磺酸盐）盐；指示剂在几分钟内分解，形成[Ni（H2O）6]

  DOI：

  10.1016/j.ica.2015.04.003

文献信息

• Accelerating Ni(ii) precatalyst initiation using reactive ligands and its impact on chain-growth polymerizations
  作者：Se Ryeon Lee、Jacob W. G. Bloom、Steven E. Wheeler、Anne J. McNeil

  DOI：10.1039/c2dt32735j

  日期：——

  designed to selectively accelerate the initiation rate without influencing the propagation rate in the chain-growth polymerization of π-conjugated monomers, were investigated. Precatalysts with electronically varied reacting groups led to faster initiation rates and narrower molecular weight distributions. Computational studies revealed that the reductive elimination rates are largely modulated by the ability

  研究了具有不同反应性配体的镍（II）配合物，该配合物可选择性地加速引发速率，而不会影响π共轭单体的链增长聚合反应中的传播速率。具有电子变化的反应基团的预催化剂导致更快的引发速率和更窄的分子量分布。计算研究表明，还原消除速率主要受两个反应芳烃在还原消除过程中稳定催化剂上不断增加的电子密度的能力的调节。总体而言，这些研究提供了对交叉偶联反应（还原消除）的关键机理步骤的认识，并强调了引发在受控链增长聚合中的重要性。
• Design and Synthesis of Monofunctionalized, Water-Soluble Conjugated Polymers for Biosensing and Imaging Applications
  作者：Christopher A. Traina、Ronald C. Bakus、Guillermo C. Bazan

  DOI：10.1021/ja202877q

  日期：2011.8.17

  Water-soluble conjugated polymers with controlled molecular weight characteristics, absence of ionic groups, high emission quantum yields, and end groups capable of selective reactions of wide scope are desirable for improving their performance in various applications and, in particular, fluorescent biosensor schemes. The synthesis of such a structure is described herein. 2-Bromo-7-iodofluorene with octakis(ethylene glycol) monomethyl ether chains at the 9,9'-positions, i.e., compound 4, was prepared as the reactive premonomer. A high-yielding synthesis of the organometallic initiator (dppe)Ni(Ph)Br (dppe = 1,2-bis(diphenylphosphino)ethane) was designed and implemented, and the resulting product was characterized by single-crystal X-ray diffraction techniques. Polymerization of 4 by (dppe)Ni(Ph)Br can be carried out in less than 30 s, affording excellent control over the average molecular weight and polydispersity of the product. Quenching of the polymerization with [2-(trimethylsily)ethynyl]magnesium bromide yields silylacetylene-terminated water-soluble poly(fluorene) with a photoluminescence quantum efficiency of 80%. Desilylation, followed by copper-catalyzed azide-alkyne cycloaddition reaction, yields a straightforward route to introduce a wide range of specific end group functionalities. Biotin was used as an example. The resulting biotinylated conjugated polymer binds to streptavidin and acts as a light-harvesting chromophore to optically amplify the emission of Alexa Fluor-488 chromophores bound onto the streptavidin. Furthermore, the biotin end group makes it possible to bind the polymer onto streptavidin-functionalized cross-linked agarose beads and thereby incorporate a large number of optically active segments.