(+/-)-2-methoxy-2-phenylethyl acetate | 52763-08-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (+/-)-2-methoxy-2-phenylethyl acetate
• 英文别名: 2-methoxy-2-phenylethyl acetate；2-acetoxy-1-methoxy-1-phenyl-ethane；(+/-)-Essigsaeure-(2-methoxy-2-phenyl-aethylester)；(+/-)-(2-Methoxy-2-phenyl-aethyl)-acetat；2-Acetoxy-1-methoxy-1-phenyl-aethan；α-Methoxy-β-acetoxy-ethylbenzol；(2-Methoxy-2-phenylethyl) acetate
• CAS: 52763-08-3
• 化学式: C₁₁H₁₄O₃
• 分子量: 194.23
• InChiKey: AGBIXWBGICTXCB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  甲氧基苯乙酸甲酯 在 吡啶 、 lithium aluminium tetrahydride 作用下， 生成 (+/-)-2-methoxy-2-phenylethyl acetate
  参考文献：
  名称：

  Neighboring Carbon and Hydrogen. XVII. The Pinacol Rearrangement. Solvolysis of 2-Methoxy-2-phenylethyl and Related Halides^1,2

  摘要：

  DOI：

  10.1021/ja01612a006

文献信息

• Synthesis of Alkoxythallium(III) Compounds of Olefins and Their Reaction with Copper Halides and Pseudohalides
  作者：Sakae Uemura、Kazuo Zushi、Akira Tabata、Akio Toshimitsu、Masaya Okano

  DOI：10.1246/bcsj.47.920

  日期：1974.4

  prepared from styrene and α-methylstyrene with thallium(III) acetate and isobutyrate in various alcohols. I(R1=H) reacts with copper(I) iodide, bromide, chloride, cyanide and thiocyanate to afford the corresponding alkyl halides and pseudohalides, C6H5CH(OR3)CH2X [II], in various organic solvents, acetonitrile being the solvent of choice for the purpose of preparing II. The addition of potassium salt

  一些新的烯烃烷氧基铊(III)化合物，C6H5C(R1)(OR3)CH2Tl(OCOR2)2 [I]，是由苯乙烯和α-甲基苯乙烯与乙酸铊(III)和异丁酸在各种醇中制备的。I(R1=H) 与碘化铜、溴化铜、氯化铜、氰化物和硫氰酸铜反应生成相应的烷基卤化物和拟卤化物，C6H5CH(OR3)CH2X[II]，在各种有机溶剂中，乙腈是首选溶剂为了准备II。钾盐的加入对提高Ⅱ的收率有显着效果。卤代和假卤代脱卤发生在铊先前与烷基碳相连的位置。提出了一种离子协调的分子间方案作为制备 II 的反应机制。简要讨论了 I 的核磁共振和红外光谱数据。
• Enzymatic resolution of the chiral inductor 2-methoxy-2-phenylethanol
  作者：Marı́a I. Monterde、Rosario Brieva、Vı́ctor M. Sánchez、Miguel Bayod、Vicente Gotor

  DOI：10.1016/s0957-4166(02)00246-x

  日期：2002.6

  Several lipase-catalyzed processes are evaluated for the resolution of 2-methoxy-2-phenylethanol, a chiral auxiliary in the synthesis of optically active 1,4-dihydropyridines. Candida antarctica lipase B (CAL B) catalyzes the enzymatic acylation of the primary alcohol with high enantioselectivity. (C) 2002 Elsevier Science Ltd. All rights reserved.
• ARMSTRONG, DANIEL W.;LI, WEIYONG;STALCUP, APRYLL M.;SECOR, HENRY V.;IZAC,+, ANAL. CHIM. ACTA , 234,(1990) N, C. 365-380
  作者：ARMSTRONG, DANIEL W.、LI, WEIYONG、STALCUP, APRYLL M.、SECOR, HENRY V.、IZAC,+

  DOI：——

  日期：——
• METHOD FOR PRODUCING POLYETHERESTER CARBONATE POLYOLS
  申请人：BAYER INTELLECTUAL PROPERTY GMBH

  公开号：US20140329987A1

  公开（公告）日：2014-11-06

  The present invention relates to a method for producing polyetherester carbonate polyols by means of catalytic addition of carbon dioxide, alkylene oxides and cyclic anhydrides to H-functional starter compounds in the presence of double metal cyanide (DMC) catalysts.
• US7795347B2
  申请人：——

  公开号：US7795347B2

  公开（公告）日：2010-09-14