β-trifluoroacetylketene diphenyldithioacetal tetroxide | 673448-46-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: β-trifluoroacetylketene diphenyldithioacetal tetroxide
• 英文别名: 4,4-Bis(benzenesulfonyl)-1,1,1-trifluorobut-3-en-2-one
• CAS: 673448-46-9
• 化学式: C₁₆H₁₁F₃O₅S₂
• 分子量: 404.388
• InChiKey: SVLPZZVZYOKNTM-UHFFFAOYSA-N

物化性质

• 沸点：
  541.8±50.0 °C(Predicted)
• 密度：
  1.476±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  102
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  β-trifluoroacetylketene diphenyldithioacetal tetroxide 在 水 作用下， 生成 双苯磺酸甲烷
  参考文献：
  名称：

  A novel effective electrophile: β-trifluoroacetylketene diphenyldithioacetal S , S -tetroxide

  摘要：

  A synthesis of a novel electrophilic reagent-beta-trifluoroacetylketene diphenyldithioacetal S,S-tetroxide 3 is described. The reaction of 3 with various electron-rich aromatics such as 1,3-dimethoxybenzene, 2-methylthiophene, N-methylpyrrole, and 2-methylindole was investigated. In the course of these reactions an unusual migration of a phenylsulfonyl group takes place. An easy and ready for scale-up procedure for the synthesis of previously unknown beta-aryl, alpha-phenylsulphonyl substituted alpha,beta-unsaturated trifluoromethyl ketones is reported. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2003.12.022
• 作为产物：
  描述：

  β-trifluoroacetylketene S,S-acetal 在 双氧水 、 三氟乙酸酐 作用下， 以 三氟乙酸 为溶剂， 反应 3.0h， 以95%的产率得到β-trifluoroacetylketene diphenyldithioacetal tetroxide
  参考文献：
  名称：

  A novel effective electrophile: β-trifluoroacetylketene diphenyldithioacetal S , S -tetroxide

  摘要：

  A synthesis of a novel electrophilic reagent-beta-trifluoroacetylketene diphenyldithioacetal S,S-tetroxide 3 is described. The reaction of 3 with various electron-rich aromatics such as 1,3-dimethoxybenzene, 2-methylthiophene, N-methylpyrrole, and 2-methylindole was investigated. In the course of these reactions an unusual migration of a phenylsulfonyl group takes place. An easy and ready for scale-up procedure for the synthesis of previously unknown beta-aryl, alpha-phenylsulphonyl substituted alpha,beta-unsaturated trifluoromethyl ketones is reported. (C) 2003 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2003.12.022

文献信息

• A novel effective electrophile: β-trifluoroacetylketene diphenyldithioacetal S , S -tetroxide
  作者：Arkady L. Krasovsky、Sergej V. Druzhinin、Valentine G. Nenajdenko、Elizabeth S. Balenkova

  DOI：10.1016/j.tetlet.2003.12.022

  日期：2004.2

  A synthesis of a novel electrophilic reagent-beta-trifluoroacetylketene diphenyldithioacetal S,S-tetroxide 3 is described. The reaction of 3 with various electron-rich aromatics such as 1,3-dimethoxybenzene, 2-methylthiophene, N-methylpyrrole, and 2-methylindole was investigated. In the course of these reactions an unusual migration of a phenylsulfonyl group takes place. An easy and ready for scale-up procedure for the synthesis of previously unknown beta-aryl, alpha-phenylsulphonyl substituted alpha,beta-unsaturated trifluoromethyl ketones is reported. (C) 2003 Elsevier Ltd. All rights reserved.