(2,5-二甲基-噻吩-3-基)-甲醇 | 875238-39-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 中文名称: (2,5-二甲基-噻吩-3-基)-甲醇
• 英文名称: 2,5-dimethyl-3-hydroxymethylthiophene
• 英文别名: (2,5-dimethylthiophen-3-yl)methanol；3-hydroxymethyl-2,5-dimethyl-thiophene；3-Hydroxymethyl-2,5-dimethyl-thiophen
• CAS: 875238-39-4
• 化学式: C₇H₁₀OS
• mdl: MFCD11208334
• 分子量: 142.222
• InChiKey: CVQUIXMHNWJFGY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.428
• 拓扑面积：
  48.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  (2,5-二甲基-噻吩-3-基)-甲醇 在 氯化亚砜 、 氯仿 、 N,N-二甲基苯胺 、 丙酮 作用下， 生成 (2,5-dimethyl-thiophen-3-yl)-acetonitrile
  参考文献：
  名称：

  The Willgerodt Reaction in the Heterocyclic Series. I. 2,5-Dimethyl-3-thienyl Ketones

  摘要：

  DOI：

  10.1021/ja01164a026
• 作为产物：
  描述：

  2,5-二甲基噻吩 在 盐酸 、 乙醇 、 sodium ethanolate 、 溶剂黄146 作用下， 生成 (2,5-二甲基-噻吩-3-基)-甲醇
  参考文献：
  名称：

  Gol'dfarb; Kondakowa, Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1956, p. 495,498; engl. Ausg. S. 487, 489

  摘要：

  DOI：

文献信息

• POLYCYCLIC AMINES AS OPIOID RECEPTOR MODULATORS
  申请人：WANG XIAODONG

  公开号：US20180258065A1

  公开（公告）日：2018-09-13

  The present invention provides a genus of polycyclic amines that are useful as opioid receptor modulators. The compounds of the invention are useful in both therapeutic and diagnostic methods, including for treating pain, neurological disorders, cardiac disorders, bowel disorders, drug and alcohol addiction, drug overdose, urinary disorders, respiratory disorders, sexual dysfunction, psoriasis, graft rejection or cancer.

  本发明提供了一类多环胺类化合物，可用作阿片受体调节剂。该发明的化合物可用于治疗和诊断方法，包括治疗疼痛、神经系统疾病、心脏疾病、肠道疾病、药物和酒精成瘾、药物过量、泌尿系统疾病、呼吸系统疾病、性功能障碍、银屑病、移植排斥或癌症。
• MALEIMIDE-BASED COMPOUND, AND TAUTOMER OR STEREOISOMER THEREOF, DYE FOR PHOTOELECTRIC CONVERSION, AND SEMICONDUCTOR ELECTRODE, PHOTOELECTRIC CONVERSION ELEMENT AND PHOTOELECTROCHEMICAL CELL USING THE SAME
  申请人：Maeda Katsumi

  公开号：US20130056690A1

  公开（公告）日：2013-03-07

  It is an object to provide a maleimide-based compound having excellent photoelectric conversion characteristics, and a tautomer or a stereoisomer thereof, a dye for photoelectric conversion, a semiconductor electrode, a photoelectric conversion element, and a photoelectrochemical cell. In order to accomplish the above-described objects, a dye for photoelectric conversion including at least one compound represented by the following general formula (1) is provided. (In the formula (1), R 1 represents a direct bond, or a substituted or unsubstituted alkylene group. X represents an acidic group. D represents an organic group containing an electron-donating substituent. Z represents a linking group that has at least one hydrocarbon group selected from aromatic rings or heterocyclic rings).

  提供一种具有优异光电转换特性的基于马来酰亚胺的化合物，以及其互变体或立体异构体，用于光电转换的染料，半导体电极，光电转换元件和光电化学电池。为了实现上述目标，提供了一种用于光电转换的染料，其中至少包括由以下通式（1）表示的化合物之一。（在通式（1）中，R1表示直接键，或取代或未取代的烷基。X表示酸性基团。D表示含有给电子取代基的有机基团。Z表示具有至少一个选自芳香环或杂环的碳氢基团的连接基团）。
• INDOLE COMPOUND, AND PHOTOELECTRIC CONVERSION DYE USING SAME, SEMICONDUCTOR ELECTRODE, PHOTOELECTRIC CONVERSION ELEMENT, AND PHOTOELECTROCHEMICAL CELL
  申请人：Maeda Katsumi

  公开号：US20130167932A1

  公开（公告）日：2013-07-04

  Provided is an indole compound represented by the following general formula (1): wherein in formula (1), R 1 and R 2 each independently represent a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group or a substituted or unsubstituted heterocyclic group; R 3 to R 6 each independently represent a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, an alkoxy group or a hydroxy group; X represents an organic group having an acidic group; and Z represents a linking group including at least one selected from the group consisting of a substituted or unsubstituted aromatic ring, a substituted or unsubstituted heterocyclic ring, a vinylene group and an ethynylene group.

  提供的是由以下一般式（1）表示的吲哚化合物：在式（1）中，R1和R2分别独立地表示氢原子、取代或未取代的烷基基团、取代或未取代的芳基团或取代或未取代的杂环基团；R3到R6分别独立地表示氢原子、取代或未取代的烷基基团、取代或未取代的芳基团、烷氧基或羟基；X表示具有酸性基团的有机基团；Z表示包括取代或未取代的芳香环、取代或未取代的杂环环、乙烯基团和乙炔基团中至少一种的连接基团。
• 2-Phenoxy-6-thienylmethyloxypyridine derivative, process for producing the same, and herbicidal composition
  申请人：KUREHA KAGAKU KOGYO KABUSHIKI KAISHA

  公开号：EP0693490A1

  公开（公告）日：1996-01-24

  A 2-phenoxy-6-thienylmethyloxypyridine derivative of formula (I) :    wherein:    R represents hydrogen, a halogen, cyano, C₁-C₄ alkyl, C₁-C₄ alkoxy, C₁-C₄ alkylthio, C₁-C₄ haloalkyl, C₁-C₄ alkylamino, or di(C₁-C₄ alkyl)amino;    each X, which may be identical or different if n is greater than 1, represents a halogen, C₁-C₄ alkyl, C₁-C₄ alkoxy, C₁-C₄ alkylthio, or C₁-C₄ haloalkyl;    each Y, which may be identical or different if m is greater than 1, represents a halogen, C₁-C₄ alkyl, C₁-C₄ alkoxy, C₁-C₄ alkylthio, C₁-C₄ haloalkyl, C₁-C₄ haloalkoxy, or C₁-C₄ haloalkylthio;    m represents an integer of 0 to 5; and    n represents an integer of 0 to 3.

  式 (I) 的 2-苯氧基-6-噻吩基甲基氧基吡啶衍生物： 其中 R 代表氢、卤素、氰基、C₁-C₄ 烷基、C₁-C₄ 烷氧基、C₁-C₄ 烷硫基、C₁-C₄ 卤代烷基、C₁-C₄ 烷氨基或二(C₁-C₄ 烷基)氨基； 每个 X（如果 n 大于 1，可以相同或不同）代表卤素、C₁-C₄ 烷基、C₁-C₄ 烷氧基、C₁-C₄ 烷硫基或 C₁-C₄ 卤代烷基； 每个 Y 代表卤素、C₁-C₄ 烷基、C₁-C₄ 烷氧基、C₁-C₄ 硫代烷基、C₁-C₄ 卤代烷基、C₁-C₄ 卤代烷氧基或 C₁-C₄ 卤代烷硫基，如果 m 大于 1，每个 Y 可以相同或不同； m 代表 0 至 5 的整数；以及 n 代表 0 至 3 的整数。
• Organic compound, crystal dielectric layer and capacitor
  申请人：Capacitor Sciences Incorporated

  公开号：US10026553B2

  公开（公告）日：2018-07-17

  The present disclosure provides an organic compound characterized by electronic polarizability and having a following general structural formula: where Core is an aromatic polycyclic conjugated molecule, R1 is group providing solubility of the organic compound in an organic solvent, n is 1, 2, 3, 4, 5, 6, 7 or 8, R2 is substitute located in apex positions, R3 and R4 are substitutes located in side (lateral) positions and, the core has flat anisometric form and the R2 substitutes are selected from hydrogen and electrophilic groups (acceptors) and R3 substitutes and R4 substitutes are independently selected from hydrogen and nucleophilic groups (donors) or vice versa R3 substitutes and R4 substitutes are independently selected from hydrogen and nucleophilic groups (donors) and R2 substitutes are selected from hydrogen and electrophilic groups (acceptors), and the substitutes R2, R3 and R4 cannot all be hydrogen.

  本公开提供了一种有机化合物，其特点是具有电子极化性，并具有以下结构通式： 其中 Core 是芳香族多环共轭分子，R1 是提供有机化合物在有机溶剂中溶解度的基团，n 是 1、2、3、4、5、6、7 或 8，R2 是位于顶点位置的取代基，R3 和 R4 是位于侧（横向）位置的取代基，并且、核心具有扁平异形，R2 取代基选自氢和亲电基团（受体），R3 取代基和 R4 取代基独立选自氢和亲核基团（供体），反之亦然，R3 取代基和 R4 取代基独立选自氢和亲核基团（供体），R2 取代基选自氢和亲电基团（受体），且取代基 R2、R3 和 R4 不能都是氢。