剧毒不订 | 37785-57-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 剧毒不订
• 中文别名: 2,4,5-三氯苯氧基乙酸钾；2,4,5-三氯苯氧乙酸钾盐
• 英文名称: potassium 2,4,5-trichlorophenoxyacetate
• 英文别名: potassium;2-(2,4,5-trichlorophenoxy)acetate
• CAS: 37785-57-2
• 化学式: C₈H₄Cl₃O₃*K
• 分子量: 293.575
• InChiKey: LUDUIQAQFKIYND-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -1.22
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  49.4
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2918990090

SDS

---

Section I.Chemical Product and Company Identification
Chemical Name 2,4,5-Trichlorophenoxyacetic Acid Potassium Salt
Portland OR
Synonym Potassium 2,4,5-trichlorophenoxyacetic
Chemical Formula C8H4Cl3KO3
CAS Number 37785-57-2

---

Section II. Composition and Information on Ingredients
Chemical Name CAS Number Percent (%) TLV/PEL Toxicology Data
2,4,5-Trichlorophenoxyacetic Acid Potassium Salt 37785-57-2 Min. 98.0 (T) Not available. Not available.

---

Section III. Hazards Identification
Acute Health Effects Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
CARCINOGENIC EFFECTS : Not available.
Chronic Health Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.

---

Section IV. First Aid Measures
Eye Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical attention.
Skin Contact In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing
before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Inhalation If the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not
improve.
Ingestion INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.
Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the
toxic material was ingested; the absence of such signs, however, is not conclusive.

---

Section V. Fire and Explosion Data
Auto-Ignition Not available.
Flammability May be combustible at high temperature.
Flammable Limits
Flash Points Not available.
Not available.
Combustion Products These products are toxic carbon oxides (CO, CO 2), halogenated compounds. Some metallic oxides.
WARNING: Highly toxic HCl gas is produced during combustion.
Fire Hazards
Not available.
Explosion Hazards Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media
SMALL FIRE: Use DRY chemical powder.
and Instructions LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
Consult with local fire authorities before attempting large scale fire-fighting operations.
Continued on Next Page
2,4,5-Trichlorophenoxyacetic Acid Potassium Salt

---

Section VI. Accidental Release Measures
Spill Cleanup Harmful material.
Instructions Use a shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any
contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on
disposal.

---

Section VII. Handling and Storage
Handling and Storage HARMFUL. Keep away from heat. Mechanical exhaust required. When not in use, tightly seal the container and store in
a dry, cool place. Avoid excessive heat and light. Do not breathe dust.
Information
Always store away from incompatible compounds such as oxidizing agents.

---

Section VIII. Exposure Controls/Personal Protection
Engineering Controls Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection Splash goggles. Lab coat. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult
a specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
Exposure Limits Not available.

---

Section IX. Physical and Chemical Properties
Solubility
Physical state @ 20°C Solid. (Off-white powder.) Not available.
Not available.
Specific Gravity
Molecular Weight 293.57 Partition Coefficient Not available.
Boiling Point Not available. Vapor Pressure Not applicable.
Melting Point Not available. Vapor Density Not available.
Not available. Volatility Not available.
Refractive Index
Critical Temperature Odor Not available.
Not available.
Not available. Not available.
Viscosity Taste

---

Section X. Stability and Reactivity Data

---

This material is stable if stored under proper conditions. (See Section VII for instructions)
Stability
Conditions of Instability
Avoid excessive heat and light.
Incompatibilities
Reactive with oxidizing agents.

---

Section XI. Toxicological Information
RTECS Number Not available.
Routes of Exposure Eye Contact. Ingestion. Inhalation.
Not available.
Toxicity Data
Chronic Toxic Effects CARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.
Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death.
Acute Toxic Effects
Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.

---

Section XII. Ecological Information
Ecotoxicity Not available.
Not available.
Environmental Fate
Continued on Next Page
2,4,5-Trichlorophenoxyacetic Acid Potassium Salt

---

Section XIII. Disposal Considerations
Waste Disposal Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a
combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state and local regulations when disposing of the substance.

---

Section XIV. Transport Information
DOT Classification Not a DOT controlled material (United States).
PIN Number Not applicable.
Proper Shipping Name
Not applicable.
Packing Group (PG) Not applicable.
DOT Pictograms

---

Section XV. Other Regulatory Information and Pictograms
TSCA Chemical Inventory This product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40
CFR 720.36 (C) for those products not on the inventory list:
(EPA)
(i) These products are supplied solely for use in research and development by or under the supervision of a technically
qualified individual as defined in 40 CFR 720.0 et sec.
(ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be
supplied on an MSDS sheet.
WHMIS Classification Not available.
(Canada)
EINECS Number (EEC) 253-667-7
EEC Risk Statements R20/21/22- Harmful by inhalation, in contact with skin and if swallowed.

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  N-甲基邻苯二甲酰亚胺 、 剧毒不订 以 水 、 丙酮 为溶剂， 反应 3.0h， 以51%的产率得到3-Hydroxy-2-methyl-3-[(2,4,5-trichlorophenoxy)methyl]isoindol-1-one
  参考文献：
  名称：

  苯氧乙酸酯向N-甲基邻苯二甲酰亚胺的光脱羧加成反应

  摘要：

  将各种苯氧乙酸酯光加成到N-甲基邻苯二甲酰亚胺上可得到相应的羟基邻苯二甲酰亚胺，产率为21-93％。对于观察到的低非对映选择性的一系列2-取代的苯氧基乙酸酯，研究了分子间加成的非对映选择性。用苯甲醚和含醚的邻苯二甲酰亚胺进行的比较实验证实，关键的电子转移步骤是从羧酸酯官能团发生的。

  DOI：

  10.1016/j.tetlet.2009.09.067

文献信息

• Dicationic Herbicidal Ionic Liquids Comprising Two Active Ingredients Exhibiting Different Modes of Action
  作者：Juliusz Pernak、Michał Niemczak、Tomasz Rzemieniecki、Katarzyna Marcinkowska、Tadeusz Praczyk

  DOI：10.1021/acs.jafc.1c07750

  日期：2022.3.2

  and dodecylmethylene-1,12-bis(decyldimethylammonium), including two different herbicidal anions exhibiting different modes of action, were synthesized and characterized. One herbicide incorporated into the HILs was a tribenuron-methyl belonging to ALS inhibitors, while the second herbicidal anion was a synthetic auxin that acts as a growth regulator, namely 2,4-dichlorophenoxyacetate (2,4-D), 2-(2,

  在本研究的框架内，合成了含有四亚甲基-1,4-双（癸基二甲基铵）和十二烷基亚甲基-1,12-双（癸基二甲基铵）的双阳离子除草离子液体（HIL），包括两种表现出不同作用模式的不同除草阴离子和特点。加入 HIL 的一种除草剂是属于 ALS 抑制剂的苯磺隆，而第二种除草阴离子是一种合成生长素，可作为生长调节剂，即 2,4-二氯苯氧基乙酸酯 (2,4-D)、2-(2 ,4-二氯苯氧基)丙酸酯, (2,4-DP), 2,4,5-三氯苯氧基乙酸酯 (2,4,5-T), 4-氯-2-甲基苯氧基乙酸酯 (MCPA), 2-(4-氯- 2-甲基苯氧基）丙酸酯（MCPP）和4-氯苯氧基乙酸酯（4-CPA）。发现所得产品不稳定且分解，这可归因于苯磺隆的磺酰脲桥中存在一个额外的甲基。合成的 HILs 对极性和半极性溶剂表现出良好的亲和力，乙酸乙酯和己烷是唯一不溶解 HILs 的溶剂。温室测试表明，大多数获得的 HIL
• Repurposing amine and carboxylic acid building blocks with an automatable esterification reaction
  作者：Andrew McGrath、Rui Zhang、Khadija Shafiq、Tim Cernak

  DOI：10.1039/d2cc05670d

  日期：——

  amines and carboxylic acids that complement the popular amide coupling can significantly expand accessible chemical space if they yield products distinct from the classic R–NHC(O)–R′ amide arrangement. Here we have developed an amine–acid esterification reaction based on pyridinium salt activation of amine C–N bonds to create products of type R–OC(O)–R′ upon reaction with alkyl and aryl carboxylic acids

  结合胺和羧酸的新方法补充了流行的酰胺偶联，如果它们产生的产物不同于经典的 R-NHC(O)-R' 酰胺排列，则可以显着扩展可及的化学空间。在这里，我们开发了一种基于胺 C-N 键的吡啶盐活化的胺-酸酯化反应，在与烷基和芳基羧酸反应时产生 R-OC(O)-R' 类型的产物。正如开源机器人的自动化所证明的那样，该协议是健壮和简便的。
• Granular controlled release agrochemical compositions and process for the preparation thereof
  申请人：Everris International B.V.

  公开号：EP2545775A2

  公开（公告）日：2013-01-16

  A granular agrochemical composition is disclosed including a granular core material having a water soluble portion with a first coating layer applied on the surface of the core material and a second coating layer applied on the surface of the first coating layer. The first coating layer includes a wax composition having a biologically active ingredient incorporated therein and the second coating layer includes a polymeric composition.; The granular agrochemical composition exhibits a controlled rate of release of the biologically active ingredient therefrom over a period greater than about 30 days from the date of initial exposure of the granular composition to moisture whereby essentially all of the biologically active ingredient incorporated in the wax material of the first coating layer is released from the granular composition before the water soluble portion of the granular core material is released from the granular composition.

  本发明公开了一种颗粒状农用化学品组合物，包括一种颗粒状芯材，芯材具有水溶性部分，芯材表面涂有第一涂布层，第一涂布层表面涂有第二涂布层。颗粒状农用化学品组合物显示出生物活性成分从颗粒状组合物中释放的可控速率，从颗粒状组合物最初暴露于湿气之日起超过约 30 天的时间内，颗粒状组合物中的生物活性成分基本上全部从第一涂布层的蜡材料中释放出来，然后颗粒状芯材的水溶性部分才从颗粒状组合物中释放出来。
• Controlled release products and processes for the preparation thereof
  申请人：OMS Investments, Inc.

  公开号：US20020168318A1

  公开（公告）日：2002-11-14

  A controlled release product is provided having a suppressed initial release period and a predetermined longevity. The product includes a particulate water soluble core material and a semi-permeable coating layer applied on the core material for controlling the release rate of the core material. The semi-permeable coating layer is formulated in accordance with the following equation to provide a release rate wherein initial release of core material from the product is suppressed so that less than about 15 weight percent of core material is released from the product within a 24 hour period after application of the product and wherein longevity of release, at ambient temperature, between the time of application and the time at which at least about 75 weight percent of the core material is released from the product is 60 days or less: 1 WVTR = φ · δ π ⁢ ⁢ d 2 wherein: (i) WVTR is the water vapor transmission rate of the semi-permeable coating expressed in grams·&mgr;m/meters 2 ·day; (ii) &phgr; is the water diffusion rate (water flux) through the semi-permeable coating expressed in grams/day; (iii) &dgr; is the thickness of the coating layer expressed in &mgr;m; and (iv) d is the average diameter of the particulate core material expressed in meters.

  一种控释产品具有被抑制的初始释放期和预定的持久性。该产品包括颗粒状水溶性芯材和涂在芯材上用于控制芯材释放率的半透涂层。半透性涂层层按下式配制，以提供一种释放率，其中芯材从产品中的初始释放被抑制，从而在施用产品后的 24 小时内从产品中释放的芯材少于约 15 重量百分比，并且在环境温度下，从施用时间到至少约 75 重量百分比的芯材从产品中释放的时间之间的释放寿命为 60 天或更短： 1 WVTR = φ &CenterDot； δ π &it； &it； d 2 其中 (i) WVTR 是半透涂料的水蒸气透过率，以克-&mgr;米/米表示 2 -天； (ii) &phgr；是通过半透涂层的水扩散率（水通量），单位为克/天； (iii) &dgr；是涂层的厚度，单位为米 (iv) d 是颗粒核心材料的平均直径，以米为单位。
• Influence of trialkylsilyl- and silatranylmethylesters of aryloxy-, arylthio-, and arylaminoacetic acids on the aggregation of thrombocytes
  作者：T. V. Nefedova、B. Shirchin、V. B. Kazimirovskaya、M. G. Voronkov

  DOI：10.1007/bf00759002

  日期：1984.3

表征谱图