3,4-dihydroxyanthraquinone-2-carboxylic acid | 6373-38-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 3,4-dihydroxyanthraquinone-2-carboxylic acid
• 英文别名: 3,4-dihydroxy-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid；3.4-Dioxy-anthrachinon-carbonsaeure-(2)；3,4-Dihydroxy-9,10-dioxo-9,10-dihydro-anthracen-2-carbonsaeure；Alizarin-carbonsaeure-(3)；Dioxyanthrachinoncarbonsaure；3,4-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid
• CAS: 6373-38-2
• 化学式: C₁₅H₈O₆
• 分子量: 284.225
• InChiKey: WVNZRIIMWFMRKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  112
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3,4-dihydroxyanthraquinone-2-carboxylic acid 在 manganese(IV) oxide 、 硫酸 作用下， 生成 pseudopurpurin
  参考文献：
  名称：

  DE260765

  摘要：

  公开号：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 作用下， 生成 3,4-dihydroxyanthraquinone-2-carboxylic acid
  参考文献：
  名称：

  DE260765

  摘要：

  公开号：

文献信息

• DE272301
  申请人：——

  公开号：——

  公开（公告）日：——
• Anthraquinone derivatives as ADP-competitive inhibitors of liver pyruvate kinase
  作者：Amalyn Nain-Perez、Anders Foller Füchtbauer、Liliana Håversen、Aleksei Lulla、Chunxia Gao、Josipa Matic、Leticia Monjas、Alexandra Rodríguez、Paul Brear、Woonghee Kim、Marko Hyvönen、Jan Borén、Adil Mardinoglu、Mathias Uhlen、Morten Grøtli

  DOI：10.1016/j.ejmech.2022.114270

  日期：2022.4
• [EN] ANTICANCER ANTHRAQUINONES AND METHOD OF USE THEREOF<br/>[FR] ANTHRAQUINONES ANTICANCEREUX ET LEUR METHODE D'UTILISATION
  申请人：UNIV MICHIGAN STATE

  公开号：WO2003089576A2

  公开（公告）日：2003-10-30

  Anthraquinones are described which have anticancer or antitumor activity and which are useful for inhibiting cancer cells and cells comprising tumors in vitro or in vivo. Preferably, the anthraquinones have the chemical formula (1), wherein R1, is selected from the group consisting of to hydrogen, alkyl, and substituted alkyl; R2 is a group containing 1-12 carbons selected from the group consisting of alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate and combinations thereof; and R3 is a group containing 1 to 12 carbons selected from the group consisting of methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, and combinations thereof. The preferred anthraquinones are 1-hydroxy-2-acetyl-3,6-methyl anthraquinone, 2­-acetyl-3,6-methyl anthraquinone monoacetate, 1­-hydroxy-2-acetyl-3,7-methyl anthraquinone, 2-acetyl-­3,7-methyl anthraquinone monoacetate, 1,2,8-­trihydroxy-3-methyl anthraquinone, 1,8-dihydroxy-2-0-­β-D-glucopyranoside anthraquinone, 1,2,8-trihydroxy-3-hydroxymethyl anthraquinone, and 1,8-dihydroxy-3-­carboxy anthraquinone.
• DE260765
  申请人：——

  公开号：——

  公开（公告）日：——