4-<4-Nitro-phenylethinyl>-pyridin | 2735-15-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-<4-Nitro-phenylethinyl>-pyridin
• 英文别名: Pyridine, 4-p-nitrophenylethynyl-；4-[2-(4-nitrophenyl)ethynyl]pyridine
• CAS: 2735-15-1
• 化学式: C₁₃H₈N₂O₂
• 分子量: 224.219
• InChiKey: ZZTQHSGZKBLCNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  58.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-<4-Nitro-phenylethinyl>-pyridin 在 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以40%的产率得到4-<4-Nitro-phenylethinyl>-pyridin-N-oxid
  参考文献：
  名称：

  Synthesis of optically quadratic nonlinear phenylpyridylacetylenes

  摘要：

  DOI：

  10.1021/jo00031a060
• 作为产物：
  描述：

  4-[2-(4-硝基苯基)乙烯基]吡啶 在 四氯化碳 、 溴 作用下， 生成 4-<4-Nitro-phenylethinyl>-pyridin
  参考文献：
  名称：

  Katritzky et al., Journal of the Chemical Society, 1960, p. 1516

  摘要：

  DOI：

文献信息

• Hydrazine Hydrate Accelerates Neocuproine–Copper Complex Generation and Utilization in Alkyne Reduction, a Significant Supplement Method for Catalytic Hydrogenation
  作者：Yongsheng Zhang、Jincheng Wang、Zhenjiao Yang、Zeng Zhang、Xiaoyan He、Guoliang Chen、Gang Huang、Xiuhong Lu

  DOI：10.1021/acs.joc.1c01803

  日期：2021.12.17

  Diimine (HN═NH) is a strong reducing agent, but the efficiency of diimine oxidized from hydrazine hydrate or its derivatives is still not good enough. Herein, we report an in situ neocuproine–copper complex formation method. The redox potential of this complex enable it can serve as an ideal redox catalyst in the synthesis of diimine by oxidation of hydrazine hydrate, and we successfully applied this

  二亚胺（HN=NH）是一种强还原剂，但水合肼或其衍生物氧化二亚胺的效率仍然不够好。在此，我们报告了一种原位新铜素-铜络合物形成方法。该配合物的氧化还原电位使其可以作为一种理想的氧化还原催化剂用于水合肼氧化合成二亚胺，我们成功地将该技术应用于炔烃的还原。这种还原方法显示出广泛的官能团耐受性和底物适应性以及安全性和高效性的优点。特别是含硝基、苄基、boc和硫的炔烃可以直接还原为相应的烷烃，为传统的催化加氢提供了一种有用的补充方法。除了，
• A carrier-free and recyclable protocol for the cross-coupling of terminal alkynes with arylboronic acids in H2O/TBAB
  作者：Bo-Xiao Tang、Ren-Yun Kuang、Ji-Wu Wen、Xiang Huang、Zhen-Xing Zhang、Yu-Jun Shen、Jia-Ping Chen、Wen-Ying Wu

  DOI：10.1016/j.tetlet.2019.06.047

  日期：2019.7

  A new and recyclable protocol was developed for Pd(OAc)2-catalyzed the cross-coupling reaction of terminal alkynes with arylboronic acids using environmentally friendly H2O/TBAB as reaction medium. A series of cross-coupling products containing internal acetylenic bond can be obtained with good selectivity and yield. The Pd(OAc)2/H2O/TBAB system was stable in the Sonogashira-type cross-coupling reaction

  开发了一种新的可回收的Pd（OAc）2协议，使用环境友好的H 2 O / TBAB作为反应介质，催化末端炔烃与芳基硼酸的交叉偶联反应。可以获得具有良好选择性和产率的一系列包含内部炔键的交叉偶联产物。Pd（OAc）2 / H 2 O / TBAB体系在Sonogashira型交叉偶联反应中稳定，可以使用至少三个循环，而催化性能却没有显着下降。结果表明，在合成有机化学中，不受支持和可循环使用的系统可以扩展到C C键形成的其他领域。
• Rhenium carbonyls containing pyridyl ligands incorporating an alkyne entity
  作者：Jiann T. Lin、Shih-Sheng Sun、Jiann Jung Wu、Yen-Chywan Liaw、Kuan-Jiuh Lin

  DOI：10.1016/0022-328x(96)06167-0

  日期：1996.6

  Reactions of pyridyl ligands, 4,4'-dipyridylbutadiyne (DPB), 1,4-bis(4'-pyridylethynyl)benzene (BPEB), ferrocenyl-4-pyridylacetylene (FPA), 4-nitrophenyl-4'-pyridylacetylene (NPPA) and 4-aminophenyl-4'-pyridylacetylene (APPA), with Re(CO)(5)X (X = Cl,Br), cis-Re(CO)(4)(L)Cl (L = PPh(3), P(OMe)(3)), and [Re(CO)(3)(2,2'-bipy)(MeCN)][PF6], provides fac-Re(CO)(3)(eta(1)-DPB)(2)Cl (1), fac-Re(CO)(3)(PY)(2)Br (2, PY = FPA; 3, L = NPPA; 4, L = APPA), [fac-Re(CO)(3)(PPh(3))Cl](2)(mu-PY) (5, PY = BPEB; 6, PY = DPB), [fac-Re(CO)(3)(P(OMe)(3))Cl](2)(mu-DPB) (7), fac-Re(CO)(3)(PPh(3))(PY)Cl (8, PY = NPPA; 9, PY = FPA), [fac-Re(CO)(3)(2,2'-bipy)(PY)][PF6] (10, PY = NPPA; 11, PY = APPA; 12, PY = FPA), and [(fac-Re(CO)(3)(2,2'-bipy)}(2)(mu-PY)][PF6](2) (13, PY = DPB; 14, PY = BPEB). The energy of the metal to pyridyl pi* charge-transfer (MLCT) is investigated by electronic absorption spectra and cyclic voltammetry, X-ray structural analyses for 2 . CH2Cl2 and 12 . 2H(2)O were carried out. 2 . CH2Cl2:C12H28BrClN2O3P2Fe2Re; monoclinic; P2(1)/n, Z = 4; a = 15.188(2), b = 15.100(2), c = 16.254(1) Angstrom; beta = 102.22(1)degrees; R = 0.047; Rw = 0.040. 12 . 2H(2)O: C30H21F6N3O3PFeRe; monoclinic; P2(1)/n, Z = 4; a = 19.022(4), b = 9.339(2), c = 21.111(3) Angstrom; beta = 116.156(9)degrees; R = 0.043; Rw = 0.061.
• Lin, Jiann T.; Sun, Shih-Sheng; Wu, Jiann Jung, Inorganic Chemistry, 1995, vol. 34, # 9, p. 2323 - 2333
  作者：Lin, Jiann T.、Sun, Shih-Sheng、Wu, Jiann Jung、Lee, Liangshiu、Lin, Kuan-Jiuh、Huang, Yi Fong

  DOI：——

  日期：——
• Katritzky et al., Journal of the Chemical Society, 1960, p. 1516
  作者：Katritzky et al.

  DOI：——

  日期：——