1-(1,2-二苯基乙烯基)-4-甲基苯 | 70603-14-4

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 中文名称: 1-(1,2-二苯基乙烯基)-4-甲基苯
• 英文名称: 1-(p-Tolyl)-1,2-diphenylethen
• 英文别名: 1,2-diphenyl-1-(p-tolyl)ethene；(1-(p-tolyl)ethene-1,2-diyl)dibenzene；1,2-Diphenyl-1-p-tolyl-aethen；1,1'-[1-(4-Methylphenyl)ethene-1,2-diyl]dibenzene；1-(1,2-diphenylethenyl)-4-methylbenzene
• CAS: 70603-14-4
• 化学式: C₂₁H₁₈
• 分子量: 270.374
• InChiKey: HGGBVSDUNPLLCZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-(1,2-二苯基乙烯基)-4-甲基苯 在 镍 氢气 作用下， 以 环己烷 为溶剂， 20.0 ℃ 、9.5 MPa 条件下， 以95%的产率得到1-(1,2-二苯基乙基)-4-甲基苯
  参考文献：
  名称：

  Effenberger, Franz; Russ, Werner, Chemische Berichte, 1982, vol. 115, # 12, p. 3719 - 3736

  摘要：

  DOI：
• 作为产物：
  描述：

  4-甲基二苯甲酮 在 硫酸 作用下， 生成 1-(1,2-二苯基乙烯基)-4-甲基苯
  参考文献：
  名称：

  SYNTHESES WITH TRIARYLVINYLMAGNESIUM BROMIDES. TRIARYLACRYLIC ACIDS AND THE INDONES DERIVED FROM THEM

  摘要：

  DOI：

  10.1021/ja01345a046

文献信息

• Rhodium catalyzed reaction of internal alkynes with organoborons under CO atmosphere: a product tunable reaction
  作者：Levent Artok、Melih Kuş、Özge Aksın-Artok、Fatma Nurcan Dege、Fatma Yelda Özkılınç

  DOI：10.1016/j.tet.2009.09.044

  日期：2009.11

  Alkynes react with organoborons under a CO atmosphere in the presence of a rhodium(I) catalyst to afford mainly 5-aryl-2(5H)-furanones, α,β-unsaturated ketones, and indanones. The product selectivity can be tuned by modifying the reaction conditions.

  炔烃在铑（I）催化剂存在下，在CO气氛下与有机硼反应，主要生成5-芳基-2（5 H）-呋喃酮，α，β-不饱和酮和茚满酮。产物的选择性可以通过改变反应条件来调节。
• Olefin synthesis by the Pd-catalyzed cross coupling on sulfonylhydrazones with aromatic sulfinates
  作者：Hongyu Tan、Ioannis Houpis、Yunfei Li、Youchu Wang、Renmao Liu、Zhilong Chen

  DOI：10.1016/j.tetlet.2016.04.078

  日期：2016.5

  olefins by coupling of electron deficient sulfonylhydrazones with aryl sulfinate salts in the presence of a palladium(II) catalyst under aerobic conditions. This methodology obviates the need for preparation of an organometallic and separate activation of the ketone starting material via a vinyl halide or triflate. The oxidant, reagent stoichiometry, and the electronics of the sulfinate coupling partner

  这封信描述了在缺氧条件下，在钯（II）催化剂存在下，将电子缺陷的磺酰基hydr与芳基亚磺酸盐偶合来合成烯烃的方法。该方法避免了通过卤化乙烯或三氟甲磺酸酯制备有机金属和单独活化酮原料的需要。报告了氧化剂，化学计量比和亚磺酸盐偶联配偶体的电子学。
• Zirconoarylation of alkynes through <i>p</i>-chloranil-promoted reductive elimination of arylzirconates
  作者：Xiaoyu Yan、Chao Chen、Chanjuan Xi

  DOI：10.3762/bjoc.10.48

  日期：——

  A novel method for the zirconoarylation of alkynes was developed. TCQ-promoted reductive elimination of arylzirconate [LiCp₂ZrAr(RC≡CR)], which was prepared by the reaction of zirconocene–alkyne complexes with aryllithium compounds, afforded trisubstituted alkenylzirconocenes. This reaction can afford multi-substituted olefins with high stereoselectivity.

  开发了一种新颖的方法用于炔烃的锆芳基化。通过TCQ促进芳基锆酸锂化物[LiCp₂ZrAr(RC≡CR)]的还原消除，该锂化物是通过锆茂-炔基配合物与芳基锂化合物反应制备的，得到了三取代烯基锆茂。该反应可以高立体选择性地生成多取代烯烃。
• Versatile Relay and Cooperative Palladium(0)<i>N</i>-Heterocyclic Carbene/Copper(I)<i>N</i>-Heterocyclic Carbene Catalysis for the Synthesis of Tri- and Tetrasubstituted Alkenes
  作者：Mathieu Lesieur、Yannick D. Bidal、Faïma Lazreg、Fady Nahra、Catherine S. J. Cazin

  DOI：10.1002/cctc.201500268

  日期：2015.7.13

  Two new and efficient dual catalytic procedures for the synthesis of tri‐ and tetrasubstituted alkenes using aryl bromides and chlorides are reported. The formation of these vinyl arenes occurs independently in a one‐pot relay and a one‐pot cooperative procedure using well‐defined Pd and Cu N‐heterocyclic carbene (NHC) complexes. Mechanistic studies were performed to elucidate the key role of the solvent

  报道了使用芳基溴化物和氯化物合成三和四取代烯烃的两种新的高效双催化程序。这些乙烯基芳烃的形成独立发生在使用定义明确的Pd和Cu N杂环卡宾（NHC）配合物的一锅接力和一锅合作程序中。进行了机理研究，以阐明溶剂在每个过程中的关键作用以及关键中间体[Cu（链烯基硼）（NHC）]的形成，该中间体可在合作催化中与Pd-NHC助催化剂进行重金属化。
• Room-Temperature and Transition-Metal-Free Mizoroki–Heck-type Reaction. Synthesis of <i>E</i>-Stilbenes by Photoinduced C–H Functionalization
  作者：Javier F. Guastavino、María E. Budén、Roberto A. Rossi

  DOI：10.1021/jo501474w

  日期：2014.10.3

  We report a conceptually different approach toward E-stilbene syntheses by photoinduced direct C-H arylation of alkenes at rt without the addition of transition metals, with a broad range of aryl halides, including ArI, ArBr, and even ArCl. This is the first time that this reaction has been produced without extra solvent but with 18-crown-6 ether and t-BuOK in only 15 min of reaction.