Bis[(2-fluorenylmethoxy)carbonyl]hexane-1,6-diamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: Bis[(2-fluorenylmethoxy)carbonyl]hexane-1,6-diamine
• 英文别名: 1,6-bis[(9-fluorenylmethoxy)carbonylamino]hexane；N,N'-Bis(9H-fluorene-9-ylmethoxycarbonyl)-1,6-hexanediamine；9H-fluoren-9-ylmethyl N-[6-(9H-fluoren-9-ylmethoxycarbonylamino)hexyl]carbamate
• 化学式: C₃₆H₃₆N₂O₄
• 分子量: 560.693
• InChiKey: XRAMEHQSATYLEQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  42
• 可旋转键数：
  13
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,6-己二胺 、 氯甲酸-9-芴基甲酯 在 sodium carbonate 作用下， 以 1,4-二氧六环 、 水 为溶剂， 以96.7%的产率得到Bis[(2-fluorenylmethoxy)carbonyl]hexane-1,6-diamine
  参考文献：
  名称：

  NOVEL DIURETHANE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ACRYLIC RUBBER COMPOSITION CONTAINING THE SAME

  摘要：

  公开号：

  EP2243770B1

文献信息

• Nonlinear organic reaction of 9-fluorenylmethyl carbamates as base amplifiers to proliferate aliphatic amines and their application to a novel photopolymer system
  作者：Koji Arimitsu、Kunihiro Ichimura

  DOI：10.1039/b311358b

  日期：——

  A novel concept of base proliferation for improving the photosensitivity of base-sensitive materials is described by presenting the autocatalytic transformation of 9-fluorenylmethyl carbamates to aliphatic amines. A 9-fluorenylmethyl carbamate, as a base amplifier, was subjected to a base-catalysed fragmentation reaction to liberate the corresponding amine, which can then act as a catalyst for decomposing parent molecules, leading to autocatalytic decomposition. Consequently, the amine is generated from an equimolar amount of the carbamate using a catalytic amount of the same amine. 1-(9-Fluorenylmethoxycarbonyl)piperidine and 1-(9-fluorenylmethoxycarbonyl)cyclohexylamine were suitable as base amplifiers because of their thermal stability under neutral conditions and high base-catalytic reactivity. On the basis of the results, 1,3-bis[1-(9-fluorenylmethoxycarbonyl)-4-piperidyl]propane and 1,6-bis[(9-fluorenylmethoxy)carbonylamino]hexane were designed as base amplifiers which liberate aliphatic diamines to crosslink poly(glycidyl methacrylate) photochemically in the presence of a photobase generator. Addition of the base amplifiers resulted in a marked improvement of the photosensitivity characteristics of the polymer by a factor of 16 and 50, respectively.

  描述了一种新颖的基本增殖概念，以提高对基础敏感材料的光敏性，展示了9-芴乙基氨基甲酸酯向脂肪胺的自催化转化。作为基础放大器的9-芴乙基氨基甲酸酯经历了一种基础催化的断裂反应，从而释放出相应的胺，该胺可以作为催化剂分解母体分子，进而导致自催化分解。因此，从等摩尔量的氨基甲酸酯中生成胺，并利用相同胺的催化量。1-(9-芴乙氧基羧基)-哌啶和1-(9-芴乙氧基羧基)环己胺由于在中性条件下的热稳定性和高基础催化活性而适合作为基础放大器。根据结果，设计了1,3-双[1-(9-芴乙氧基羧基)-4-哌啶基]丙烷和1,6-双[(9-芴乙氧基)羧基氨基]己烷作为基础放大器，在光铵生成剂存在的情况下，释放脂肪二胺以交联聚（甘油甲基丙烯酸酯）进行光化学反应。添加基础放大器使聚合物的光敏性特性分别提高了16和50倍。
• NOVEL CARBAMATE ESTER COMPOUND AND ACRYLIC RUBBER COMPOSITION CONTAINING THE SAME
  申请人：UNIMATEC CO., LTD.

  公开号：US20220009934A1

  公开（公告）日：2022-01-13

  A carbamate ester compound represented by the general formula: Z—OCONH(CH 2 ) n NHCOO—Z  [I] wherein Z is [i], [ii], or [iii] below, and n is an integer of 2 to 10, (wherein R 1 and R 2 are each independently a lower alkyl group having 1 to 5 carbon atoms, R 3 is a hydrogen atom or a lower alkyl group having 1 to 5 carbon atoms, and a is 1 or 2). The carbamate ester compound is used as a vulcanizing agent for carboxyl group-containing acrylic rubber and improves the delay of the vulcanization rate by scorch suppression.

  通用公式表示的一个氨基甲酸酯化合物：Z—OCONH(CH2)nNHCOO—Z [I]，其中Z为下列[i]、[ii]或[iii]中的一种，n为2到10的整数（其中R1和R2分别独立为具有1到5个碳原子的低碳基团，R3为氢原子或具有1到5个碳原子的低碳基团，a为1或2）。该氨基甲酸酯化合物用作含有羧基的丙烯酸橡胶的硫化剂，并通过抑制火烧现象来改善硫化速率的延迟。
• Chemical amplification in self-strengthening materials
  申请人：The Board of Trustees of the University of Illinois

  公开号：US10377879B2

  公开（公告）日：2019-08-13

  A self-strengthening material is provided, the material comprising a polymer matrix having a plurality of chemical amplifiers dispersed throughout the polymer matrix and a plurality of triggerable reservoirs, the triggerable reservoirs capable of releasing at least one activator of the plurality of chemical amplifiers, wherein the plurality of chemical amplifiers reacts with the at least one activator to produce additional activators capable of changing the mechanical properties of the polymer matrix, and thus strengthening the material.

  提供了一种自加固材料，该材料包括聚合物基体，聚合物基体中分散有多个化学放大器和多个可触发贮槽，可触发贮槽能够释放多个化学放大器中的至少一种活化剂，其中多个化学放大器与至少一种活化剂发生反应，产生能够改变聚合物基体机械性能的附加活化剂，从而加固材料。
• Flow-Mediated Synthesis of Boc, Fmoc, and Dd<i>iv</i> Monoprotected Diamines
  作者：ThingSoon Jong、Mark Bradley

  DOI：10.1021/ol503343b

  日期：2015.2.6

  A series of monoprotected aliphatic diamines (21 examples) were synthesized via continuous flow methods. The carbamates and enamines were obtained in 45-91% yields using a 0.5 mm diameter PTFE tubular flow reactor. Using readily accessible protecting group precursors, the procedure serves as an attractive alternative to existing batch-mode synthetic routes by providing direct, multigram access to N-Boc-, N-Fmoc-, and N-Ddiv-protected compounds with productivity indexes of 1.2-3.6 g/h.
• Applications of a Nonlinear Organic Reaction of Carbamates To Proliferate Aliphatic Amines
  作者：Koji Arimitsu、Mana Miyamoto、Kunihiro Ichimura

  DOI：10.1002/1521-3773(20001002)39:19<3425::aid-anie3425>3.0.co;2-c

  日期：2000.10.2