2-<(4-methylphenyl)sulfonyl>-1,1,5,5-tetramethyl-1,5-diazapentadienium perchlorate | 130954-21-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-<(4-methylphenyl)sulfonyl>-1,1,5,5-tetramethyl-1,5-diazapentadienium perchlorate
• 英文别名: 2-(tolylsulfonyl)-1,1,5,5-tetramethyl-1,5-diazapentadienium perchlorate；[3-(dimethylamino)-2-(4-methylphenyl)sulfonylprop-2-enylidene]-dimethylazanium;perchlorate
• CAS: 130954-21-1
• 化学式: C₁₄H₂₁N₂O₂S*ClO₄
• 分子量: 380.85
• InChiKey: DXBOWFUAPTVICJ-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -3.24
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  123
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  2-<(4-methylphenyl)sulfonyl>-1,1,5,5-tetramethyl-1,5-diazapentadienium perchlorate 生成 (E,E)-1-(dimethylamino)-2-<(4-methylphenyl)sulfonyl>-1,3-pentadiene
  参考文献：
  名称：

  GUPTON, JOHN T.;RIESINGER, STEVE W.;SHAH, AJIT S.;GALL, JOHN E.;BEVIRT, K+, J. ORG. CHEM., 56,(1991) N, C. 976-980

  摘要：

  DOI：
• 作为产物：
  描述：

  对甲苯磺酰乙酸 、 N,N-二甲基甲酰胺 在 sodium perchlorate 、 三氯氧磷 作用下， 生成 2-<(4-methylphenyl)sulfonyl>-1,1,5,5-tetramethyl-1,5-diazapentadienium perchlorate
  参考文献：
  名称：

  The preparation and some reactions of 2-(arylsulfonyl)vinamidinium salts

  摘要：

  The preparation of novel 2-(arylsulfonyl)vinamidinium salts is described. The reactions of these materials with amidines, hydrazine, hydroxylamine, sodium borohydride, and Grignard reagents are presented along with an evaluation of their chemical behavior as compared to the 2-arylvinamidinium salts.

  DOI：

  10.1021/jo00003a015

文献信息

• A new route to 1,5-disubstituted 4-arylsulfonylpyrazoles by lithiation of 1-methyl-4-arylsulfonylpyrazoles
  作者：Michael G. Hoffmann

  DOI：10.1016/0040-4020(95)00540-o

  日期：1995.8

  The arylsulfonylvinamidinium salts 1 reacted with hydrazine in refluxing ethanol to give rise to 4-arylsulfonylpyrazoles 2 in reasonable yield. Regioselective lithiation of N-methylpyrazoles 3 with LDA followed by treatment with various electrophiles afforded the corresponding 1,5-disubstituted 4-arylsulfonylpyrazoles 5 in good yield.
• Efficient One-Pot Synthesis of Substituted Pyrido[2,3-d]pyrimidines from Vinamidinium and Chloropropeniminium Salts
  作者：Mohamed Adnen Hadj Ayed、Thouraya Gmiza、Jamel Eddine Khiari、Béchir Ben Hassine

  DOI：10.1080/00397911.2010.545163

  日期：2012.6.15

  A novel and efficient one-pot preparation of 6-substituted pyrido-[2,3-d]pyrimidines by cyclocondensation of 6-amino-1,3-dimethyluracil with symmetrical vinamidinium salts under basic conditions has been developed. Regioselectivity was observed with an unsymmetrical chloropropeniminium salt.
• GUPTON, JOHN T.;RIESINGER, STEVE W.;SHAH, AJIT S.;GALL, JOHN E.;BEVIRT, K+, J. ORG. CHEM., 56,(1991) N, C. 976-980
  作者：GUPTON, JOHN T.、RIESINGER, STEVE W.、SHAH, AJIT S.、GALL, JOHN E.、BEVIRT, K+

  DOI：——

  日期：——
• The preparation and some reactions of 2-(arylsulfonyl)vinamidinium salts
  作者：John T. Gupton、Steve W. Riesinger、Ajit S. Shah、John E. Gall、Kathy M. Bevirt

  DOI：10.1021/jo00003a015

  日期：1991.2

  The preparation of novel 2-(arylsulfonyl)vinamidinium salts is described. The reactions of these materials with amidines, hydrazine, hydroxylamine, sodium borohydride, and Grignard reagents are presented along with an evaluation of their chemical behavior as compared to the 2-arylvinamidinium salts.