N-Phenyl-N'-pyridin-2-ylmethyl-benzamidine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-Phenyl-N'-pyridin-2-ylmethyl-benzamidine
• 英文别名: N-phenyl-N'-(pyridin-2-ylmethyl)benzenecarboximidamide
• 化学式: C₁₉H₁₇N₃
• 分子量: 287.364
• InChiKey: OYQDZBIWDKOAQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  tetrakis(dimethylamido)titanium(IV) 、 N-Phenyl-N'-pyridin-2-ylmethyl-benzamidine 以 甲苯 为溶剂， 以94%的产率得到
  参考文献：
  名称：

  Titanium Bis(amidinates) Bearing Electron Donating Pendant Arms as Catalysts for Stereospecific Polymerization of Propylene

  摘要：

  A series of titanium bis(amidinate) complexes containing pendant arms as one of the amidinate N substituents have been prepared and studied in the polymerization of propylene after their activation with MAO and other cocatalysts. The type of pendant arm greatly influences the reactivity and stereospecificity of the resulting polymers. The effect of the cocatalyst nature, its amount, and the time of the reaction have a dramatic effect on the reactivity of a titanium bis(amidinate) bis(dimethylamido) precatalyst containing a furyl group at the pendant arm.

  DOI：

  10.1021/om401165g
• 作为产物：
  描述：

  苯甲酰氯 在 盐酸 、 氯化亚砜 作用下， 以 二氯甲烷 为溶剂， 生成 N-Phenyl-N'-pyridin-2-ylmethyl-benzamidine
  参考文献：
  名称：

  Titanium Bis(amidinates) Bearing Electron Donating Pendant Arms as Catalysts for Stereospecific Polymerization of Propylene

  摘要：

  A series of titanium bis(amidinate) complexes containing pendant arms as one of the amidinate N substituents have been prepared and studied in the polymerization of propylene after their activation with MAO and other cocatalysts. The type of pendant arm greatly influences the reactivity and stereospecificity of the resulting polymers. The effect of the cocatalyst nature, its amount, and the time of the reaction have a dramatic effect on the reactivity of a titanium bis(amidinate) bis(dimethylamido) precatalyst containing a furyl group at the pendant arm.

  DOI：

  10.1021/om401165g

文献信息

• Tunable zinc benzamidinate complexes: coordination modes and catalytic activity in the ring-opening polymerization of l-lactide
  作者：Chen-Chieh Chang、Ming-Tsz Chen、Tzu-Lun Huang、Chi-Tien Chen

  DOI：10.1039/d4dt00188e

  日期：——

  structures of 1–4 and 7 were determined via single-crystal X-ray diffraction. Altering benzamidinate substituents modifies both coordination modes and catalytic activities in ring-opening polymerization of L-lactide. Specifically, complex 7 exhibits enhanced catalytic activity at 25 °C using 100 equivalents of L-lactide with a turnover frequency of 1820 h−1.

  合成了七种具有或缺乏侧臂功能的不对称苯甲脒酸锌配合物。使用等摩尔锌试剂产生不同的双核基序 [(C 6 H 5 -C = NC 6 H 5 )ZnEt] 2 (R = t Bu, 1 ; (CH 2 ) 2 OMe, 2 ; (CH 2 ) 2 NMe 2 , 3 ).一半的锌试剂产生双核 [(C 6 H 5 -C = NC 6 H 5 ) 2 Zn] 2 (R = t Bu, 4 ) 或单核锌双(螯合物)络合物 (R = (CH 2 ) 2 OMe, 5 ；(CH 2 ) 2 NMe 2 ， 6 ；CH 2 Py， 7 )。通过单晶 X 射线衍射确定了1-4和7的分子结构。改变苯甲脒取代基会改变L-丙交酯开环聚合中的配位模式和催化活性。 具体而言，配合物7在25℃下使用100当量的L-丙交酯时表现出增强的催化活性，周转频率为1820 h -1 。
• Palladacycles bearing pendant benzamidinate ligands as catalysts for the Suzuki and Heck coupling reactions
  作者：Kai-Min Wu、Chi-An Huang、Kuo-Fu Peng、Chi-Tien Chen

  DOI：10.1016/j.tet.2005.06.069

  日期：2005.10

  Three pendant benzamidines [Ph-C(=NC6H5)-NH(CH2)(2)NMe2}] (1), [Ph-C(=NC6H5)-NH(CH2PY)}] (2) and [Ph-C (=NC6H5)-NH(o-C6H4)(oxazoline)}] (3) are described. Reactions of 1, 2 or 3 with one molar equivalent of Pd(OAc)(2) in THF give the palladacyclic complexes [Ph-C-NH(eta(1)-C6H4)} =N(CH2)(2)NMe2}]Pd(OAc) (4), [Ph-CNH(eta(1)-C6H4} =N (CH2Py)}]Pd(OAc) (5) and [Ph-C-NH(eta(1)-C6H4)} =N(o-C6H4)(oxazoline)}]Pd(OAc) (6), respectively. Treatment of 4, 5 or 6 with excess of LiCl in chloroform affords [Ph-C-NH(eta(1)-C6H4)} =N(CH2)(2)NMe2}]PdCl (7), [Ph-C-NH(eta(1)-C6H4} =N(CH2Py}]PdCl (8) and [Ph-CNH(eta(1)- C6H4)} =N(o-C6H4)(oxazoline)}]PdCl (9). The crystal and molecular structures are reported for compounds 1, 3, 5, 6 and 7. The application of these palladacyclic complexes to the Suzuki and Heck coupling reactions was examined.(c) 2005 Elsevier Ltd. All rights reserved.