[⁹⁹TcCl₃(MeCN)(PPh₃)₂] | 122070-40-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [⁹⁹TcCl₃(MeCN)(PPh₃)₂]
• CAS: 122070-40-0；125355-65-9
• 化学式: C₃₈H₃₃Cl₃NP₂Tc
• 分子量: 770.993
• InChiKey: WKIBXZOOAVIIPR-KTTJZPQESA-K

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [⁹⁹TcCl₃(MeCN)(PPh₃)₂] 、 4-tert-butyl-2,6-bis(3-tert-butylpyridin-2-yl)pyridine 以 乙二醇二甲醚 为溶剂， 以96%的产率得到(99)TcCl3(4,4',4''-tris(tert-butyl)terpyridine)
  参考文献：
  名称：

  Barrera, Joseph; Burrell, Anthony K.; Bryan, Jeffrey C., Inorganic Chemistry, 1996, vol. 35, # 2, p. 335 - 341

  摘要：

  DOI：

文献信息

• Synthesis and Characterization of [M^III(PS)₂(L)] Mixed-Ligand Compounds (M = Re, ⁹⁹Tc; PS = Phosphinothiolate; L = Dithiocarbamate) as Potential Models for the Development of New Agents for SPECT Imaging and Radiotherapy
  作者：N. Salvarese、N. Morellato、A. Venzo、F. Refosco、A. Dolmella、C. Bolzati

  DOI：10.1021/ic400094s

  日期：2013.6.3

  The synthesis and characterization of a new series of neutral, six-coordinated mixed-ligand compounds [MIII(PS)2(L)] (M = Re; 99Tc), where PS is bis(arylalkyl)- or trialkylphosphinothiolate and L is dithiocarbamate, are reported. Stable [MIII(PS)2(L)] complexes were easily synthesized, in good yield, starting from precursors where the metal was in different oxidation states (III, V, and VII), involving

  一系列新的中性，六配位混合配体化合物[M III（PS）2（L）]（M = Re; 99 Tc）的合成和表征，其中PS是双（芳烷基）-或三烷基硫代磷酸酯，L是二硫代氨基甲酸酯，据报道。从金属处于不同氧化态（III，V和VII）的前体开始，容易合成高收率的稳定[M III（PS）2（L）]配合物，涉及配体交换和/或氧化还原-取代反应。通过元素分析，阳离子电喷雾电离质谱，多核NMR光谱，循环伏安法和X射线衍射分析对化合物进行表征。所有配合物均由[MIII（PS）2 ] +部分，其中两个硫代硫醇盐配体紧密结合到金属上，其余两个位置被二硫代氨基甲酸酯螯合物饱和，还带有庞大的生物活性分子[例如，（2-甲氧基苯基）哌嗪]。X射线分析是对四种不同的Re / 99 Tc化合物的晶体样品进行的，它们具有扭曲的三角棱柱几何形状，并带有P 2 S 4配位体。从相应的过金属酸盐阴离子开始，在温和的反应条件下以高收率轻松制备这些[M
• Synthesis and reactions of trigonal-bipyramidal rhenium and technetium complexes with a tripodal, tetradentate NS3 ligand
  作者：Hartmut Spies、Matthias Glaser、Hans-Jürgen Pietzsch、F.Ekkehardt Hahn、Thomas Lügger

  DOI：10.1016/0020-1693(95)04571-6

  日期：1995.12

  trigonal-bipyramidal complexes of technetium and rhenium with the tripodal, tetradentate ligand 2,2′,2″-nitrilotris(ethanethiol), N(CH2CH2SH)3 (H31) have been synthesized and characterized. The technetium complex [99Tc(1) (PPh3)] (2) can be obtained by reduction of K99TcO4 with PPh3 in the presence of H31 or by substitution reaction starting from [99TcCl3(PPh3)2(NCMe)]. The trigonal-bipyramidal complex 2, C24H27NPS3Tc

  已合成并表征了and和，与三脚架，四齿配体2,2'，2''-硝腈（乙硫醇），N（CH 2 CH 2 SH）3（H 3 1）的中性，三角-双锥体络合物。complex络合物[ 99 Tc（1）（PPh 3）]（2）可以通过在H 3 1存在下用PPh 3还原K 99 TcO 4或通过从[ 99 TcCl 3（PPh 3）开始的取代反应来获得）2（（NCMe）]。三方-双锥复杂2，C 24 H ^ 27 NPS 3 Tc时，结晶在斜空间群P 2 1 / Ç用。hen络合物[Re（1）（PR 3）]（3）（PR 3 = PPh 3（3a，PMe 2 Ph（3b），PMePH 2（3c），P（n-Bu）3（3d），P（类似于derivative衍生物2获得了OEt）3 3e））通过在H 3 1存在下用膦PR 3还原NH 4 ReO 4。复杂的图3a，C 24 ħ 27 NPReS 3，结晶的单斜晶系空间群P
• Tc(IV)Cl4(PPh3)2 and Tc(III)Cl3(CH3CN)(PPh3)2 as precursors of trans dioxo technetium(V) complexes with chelating amines and tetraazamacrocycles
  作者：Françoise Riché、Michel Vidal、Cristina Bolzati、Licia Uccelli、Andrea Marchi、Adriano Duatti

  DOI：10.1016/0020-1693(94)04346-w

  日期：1995.3

  The trans dioxo complexes [TcO2(L)](+) (L = 1,4,8,11-tetraazacyclotetradecane (cyclam), 1,4,8,11-tetraazacyclotetradecane-5-one, 1 4,8,11-tetraazacyclotetradecane-5,7-dione) have been prepared through a new alternative route involving the reaction of excess of the appropriate ligand with the complexes [TcCl4(PPh(3))(2)] and [TcCl3(CH3CN)(PPh(3))(2)] in CH3CN solution, at room temperature. The yields of formation of the final products obtained through this new synthetic method (30-55%) are significantly higher than that found in the synthesis of the complex [TcO2(cyclam)](+) (7%) obtained through a previously reported procedure involving pertechnetate reduction by Na2S2O3 in alkaline solution and in the presence of the ligand or by substitution reaction onto the mono-oxo complex [TcOCl4](-). The new synthetic method was also efficiently applied to the synthesis of the trans dioxo complexes [TcO2(L')(2)](+) (L' = ethylenediamine, 1,3-propanediamine) and [TcO2(tad)](+) (tad = 1,5,8,12-tetraazadodecane), containing bidentate and tetradentate chelating amines, giving final yields similar to those obtained using [TcOCl4](-) as starting substrate. These results indicate that the complexes [TcCl4(PPh(3))(2)] and [TcCl3(CH3CN)(PPh(3))(2)] are superior precursors for the synthesis, at macroscopic level, of trans dioxo Tc(V) complexes with tetraazamacrocyclic ligands as compared to [TcO4](-) and [TcOCl4](-). All the complexes have been characterized by elemental analysis, FTIR and mass spectra, and magnetic susceptibility measurements in solution.
• An unexpected by-product obtained during the preparation of technetium(III) boronic acid adducts of dioximes. The single crystal structure of TcCl(DMG)2(BDI)BEt (DMG=dimethylglyoxime, BDI=butane-2, 3-dione imine-oxime)
  作者：K.E. Linder、D.P. Nowotnik、M.F. Malley、J.Z. Gougoutas、A.D. Nunn

  DOI：10.1016/s0020-1693(00)80261-3

  日期：1991.12

  An unusual Tc(III) boron-capped imine-oxime complex has been isolated from the reaction of (TcCl3)-Tc-99(CH3CN)(PPh3)2, dimethyl glyoxime (DMG) and ethyl boronic acid (EtB(OH)2). A single crystal X-ray structure analysis of this molecule (TcCl)-Tc-99(DMG)2(BDI)BEt) (BDI = butane-2,3-dione imine-oxime) shows it to be seven coordinate: TcClC14H25N6O5B, a = 9.073(2), b = 23.686(5), c = 19.539(6) angstrom; beta = 93.77(2)-degrees, P2(1)/n, Z = 8. Its structure is very similar to that of previously reported Tc(III) complexes (TcCl)-Tc-99(dioxime)3BR), except that one dioxime ligand on the molecule has been reduced to an imineoxime.