N-methyl-4-(1-phenylethyl)aniline | 104903-68-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-methyl-4-(1-phenylethyl)aniline
• 英文别名: N-Methyl-4-(1-phenylethyl)benzenamine
• CAS: 104903-68-6
• 化学式: C₁₅H₁₇N
• 分子量: 211.307
• InChiKey: ZUCIXHLZGUPQOZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-(1-phenylethyl)aniline 生成 N-methyl-4-(1-phenylethyl)aniline
  参考文献：
  名称：

  ALY, M. M.;BADR, MAHMOUD, ZARIF, A.;FAHMY, ATTIAT, M.;MAHGOUB, SAFAA, A., ACTA CHIM. HUNG., 1985, 120, N 1, 15-21

  摘要：

  DOI：

文献信息

• Process for the preparation of substituted phenols
  申请人：Daicel Chemical Industries, Ltd.

  公开号：EP1967505A1

  公开（公告）日：2008-09-10

  A substituted phenolic compound is prepared by oxidizing a substituted diarylethane compound with oxygen in the presence of a nitrogen-containing cyclic compound, and treating the oxidized product with an acid. The nitrogen-containing cyclic compound includes, as a constituent of its ring, a skeleton represented by following Formula (I): wherein X is oxygen atom or an -OR group, where R is hydrogen atom or a hydroxyl-protecting group. The substituted diarylethane compound is represented by following Formula (1): wherein each of Ring Ar1 and Ring Ar2 is independently a monocyclic or polycyclic aromatic carbocyclic ring; Y1 is an electron-donating group; Y2 is an electron-withdrawing group; "p" is an integer of 1 or more; and "q" is an integer of 0 or more. The substituted phenolic compound is represented by following Formula (2): wherein Ring Ar1, Y1, and "p" are as defined above.

  一种取代酚化合物是通过在含氮环化合物存在下氧化取代二芳乙烷化合物制备的，并且用酸处理氧化产物。含氮环化合物包括其环中的一个组分是由以下式（I）表示的骨架：其中X是氧原子或-OR基团，其中R是氢原子或羟基保护基团。取代二芳乙烷化合物由以下式（1）表示：其中Ar1环和Ar2环中的每一个独立地是单环或多环芳香碳环；Y1是电子给予基团；Y2是电子吸引基团；“p”是1或更多的整数；“q”是0或更多的整数。取代酚化合物由以下式（2）表示：其中Ar1环，Y1和“p”如上定义。
• Catalytic Alkylation of Aromatic Amines with Styrene in the Presence of Cationic Rhodium Complexes and Acid
  作者：Matthias Beller、Oliver R. Thiel、Harald Trauthwein

  DOI：10.1055/s-1999-2579

  日期：1999.2

  The first transition metal-catalyzed Friedel-Crafts alkylation of aromatic amines with styrene is reported. ortho-Alkylation of anilines occurs using catalytic amounts of [Rh(cod)2]BF4/4 PPh3 and HBF4.

  报告了首个过渡金属催化的芳香胺与苯乙烯的Friedel-Crafts烷基化反应。使用催化量的[Rh(cod)2]BF4/4 PPh3和HBF4进行苯胺的ortho-烷基化反应。
• Olifirov, D. I.; Koshchii, V. A.; Kozlikovskii, Ya. B., Journal of Organic Chemistry USSR (English Translation), 1992, vol. 28, # 6.1, p. 943 - 948
  作者：Olifirov, D. I.、Koshchii, V. A.、Kozlikovskii, Ya. B.

  DOI：——

  日期：——
• Aly, Morsy M.; Badr, Mahmoud Zarif A.; Fahmy, Attiat M., Acta Chimica Hungarica, 1985, vol. 120, # 1, p. 15 - 22
  作者：Aly, Morsy M.、Badr, Mahmoud Zarif A.、Fahmy, Attiat M.、Mahgoub, Safaa A.

  DOI：——

  日期：——
• ALY, M. M.;BADR, MAHMOUD, ZARIF, A.;FAHMY, ATTIAT, M.;MAHGOUB, SAFAA, A., ACTA CHIM. HUNG., 1985, 120, N 1, 15-21
  作者：ALY, M. M.、BADR, MAHMOUD, ZARIF, A.、FAHMY, ATTIAT, M.、MAHGOUB, SAFAA, A.

  DOI：——

  日期：——