sec-butylphenyl glycidyl ether | 36362-19-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: sec-butylphenyl glycidyl ether
• 英文别名: 2-{[2-(Butan-2-yl)phenoxy]methyl}oxirane；2-[(2-butan-2-ylphenoxy)methyl]oxirane
• CAS: 36362-19-3
• 化学式: C₁₃H₁₈O₂
• mdl: MFCD09928016
• 分子量: 206.285
• InChiKey: WAPRZVXVTPSWEB-UHFFFAOYSA-N

物化性质

• 沸点：
  302.5±25.0 °C(Predicted)
• 密度：
  1.029±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.538
• 拓扑面积：
  21.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(吲哚-3-基)-2-甲基-2-丙胺 、 sec-butylphenyl glycidyl ether 反应 0.5h， 生成 1-[[2-(3-INDOLYL)-1,1-DIMETHYLETHYL]AMINO]-3-[2-(1-METHYLPROPYL)PHENOXY]-2-PROPANOL
  参考文献：
  名称：

  Antihypertensive indole derivatives of phenoxypropanolamines with .beta.-adrenergic receptor antagonist and vasodilating activity

  摘要：

  A series of 25 aryloxypropanolamines containing the 3-indolyl-tert-butyl [i.e., 1,1-dimethyl-2-(1H-indol-3-yl)ethyl] or substituted 3-indolyl-tert-butyl moiety as the N substituent is reported. These compounds have been tested for antihypertensive activity in spontaneously hypertensive rats (SHR), beta-adrenergic receptor antagonist action in conscious normotensive rats, vasodilating activity in ganglion-blocked rats with blood pressure maintained by angiotensin II infusion, and for intrinsic sympathomimetic action (ISA) in reserpinized rats. Some of the compounds exhibit antihypertensive activity in combination with beta adrenergic receptor antagonist and vasodilating action. The structure--activity relationships in these tests are discussed.

  DOI：

  10.1021/jm00177a015
• 作为产物：
  描述：

  2-仲丁基苯酚 在 哌啶 、 sodium hydroxide 作用下， 以 四氢呋喃 为溶剂， 反应 0.67h， 生成 sec-butylphenyl glycidyl ether
  参考文献：
  名称：

  Antihypertensive indole derivatives of phenoxypropanolamines with .beta.-adrenergic receptor antagonist and vasodilating activity

  摘要：

  A series of 25 aryloxypropanolamines containing the 3-indolyl-tert-butyl [i.e., 1,1-dimethyl-2-(1H-indol-3-yl)ethyl] or substituted 3-indolyl-tert-butyl moiety as the N substituent is reported. These compounds have been tested for antihypertensive activity in spontaneously hypertensive rats (SHR), beta-adrenergic receptor antagonist action in conscious normotensive rats, vasodilating activity in ganglion-blocked rats with blood pressure maintained by angiotensin II infusion, and for intrinsic sympathomimetic action (ISA) in reserpinized rats. Some of the compounds exhibit antihypertensive activity in combination with beta adrenergic receptor antagonist and vasodilating action. The structure--activity relationships in these tests are discussed.

  DOI：

  10.1021/jm00177a015

文献信息

• Fibrous composite structure impregnated with a solvent-free curable
  申请人：Ciba-Geigy Corporation

  公开号：US05087688A1

  公开（公告）日：1992-02-11

  A fibrous composite structure impregnated with a solvent-free, curable epoxy resin matrix and comprising (a) a liquid epoxy resin or a liquid mixture of epoxy resins, (b) a liquid .beta.-hydroxyamine of formula I ##STR1## wherein X is phenyl or the radical R--O--CH.sub.2 --, wherein R is an alkyl group of 4 to 20 carbons or is phenyl or phenyl which is substituted by one or more C.sub.1 -C.sub.4 alkyl groups, a liquid mixture of .beta.-hydroxyamines of formula I or a liquid mixture of one more .beta.-hydroxyamines of formula I and of a primary monomaine different from formula I or of a primary or secondary diamine, and optionally (c) a catalytically curing tertiary amine, is virtually odourless, can be stored for several days at room temperature, and has good processing properties.

  一种纤维复合结构，浸渍有无溶剂、可固化的环氧树脂基质，包括：(a)液态环氧树脂或液态环氧树脂混合物，(b)式I的液态β-羟胺：##STR1## 其中X为苯基或基团R--O--CH.sub.2 --，R为4至20个碳原子的烷基或为苯基或苯基上取代有1个或多个C.sub.1-C.sub.4烷基的烷基；β-羟胺式I的液态混合物或一个或多个β-羟胺式I和不同于式I的一种主要单胺或一种主要或次要二胺的液态混合物；可选的(c)催化固化的三级胺。该结构几乎无气味，可在室温下存放数天，具有良好的加工性能。
• Refrigerating Machine Oil, and Working Fluid Composition for Refrigerating Machine Which is Produced Using Same
  申请人：KH NEOCHEM CO., LTD.

  公开号：US20160168500A1

  公开（公告）日：2016-06-16

  Provided is a refrigerating machine oil which comprises an ester between a polyol consisting of at least one of pentaerythritol and dipentaerythritol represented by formula (I) and 2-propylheptanoic acid, and is characterized in that the refrigerating machine oil can be used in combination with a refrigerant consisting of 1,3,3,3-tetrafluoropropene (HFO-1234ze). When the refrigerating machine oil is used in combination with a refrigerant consisting of HFO-1234ze, excellent miscibility with the refrigerant, lubricity, thermal and chemical stability and the like can be achieved.

  提供的是一种制冷机油，其包括一种酯，该酯由式（I）表示的至少含有一种戊四醇和重聚戊四醇的多元醇和2-丙基庚酸之间的酯化反应形成，其特征在于该制冷机油可以与由1,3,3,3-四氟丙烯（HFO-1234ze）组成的制冷剂结合使用。当该制冷机油与由HFO-1234ze组成的制冷剂结合使用时，可以实现与制冷剂的良好相容性、润滑性、热和化学稳定性等。
• Curable epoxy resin composition
  申请人：ASAHI DENKA KOGYO KABUSHIKI KAISHA

  公开号：EP0197458A2

  公开（公告）日：1986-10-15

  A thermosetting epoxy resin composition of one pack type is provided which contains as indispensable constituents (I) an epoxy resin containing more than one adjacent epoxy groups on the average in the molecule and (II) curing amount or curing-accelerating amount of a compound obtained by reacting (a) a specified amine/epoxy adduct with (b) phenolic , resin(s) and/or polyhydric phenol compound(s) in a weight ratio of (a) to (b) of 1/0.1 to 1/0.8. The composition of the present invention has excellent storage stability and it is curable at a relatively low temperature to form a cured product having excellent mechanical strength, adhesiveness and water resistance.

  本发明提供了一种单组分热固性环氧树脂组合物，其不可或缺的成分包括：(I) 分子中平均含有一个以上相邻环氧基团的环氧树脂；(II) 固化量或固化加速量的化合物，该化合物由(a)特定的胺/环氧加合物与(b)酚醛树脂和/或多羟基酚化合物反应而得，(a)与(b)的重量比为 1/0.1 至 1/0.8。本发明的组合物具有极佳的储存稳定性，可在相对较低的温度下固化，形成具有极佳机械强度、粘合性和耐水性的固化产品。
• Use of polyoxyalkylene glycol derivative in lubricating oil for compression-type refrigerators.
  申请人：IDEMITSU KOSAN COMPANY LIMITED

  公开号：EP0397037A2

  公开（公告）日：1990-11-14

  Disclosed is a lubricating oil for compression-type refrigerators comprising, as a main component, a polyoxyalkylene glycol derivative which has at least one constitutional unit represented by the general formula: wherein R¹ to R⁴ are as defined in the specification. Said lubricating oil for compression-type refrigerators has good miscibility with refrigerants including R-134a.

  本发明公开了一种用于压缩式冰箱的润滑油，其主要成分包括聚氧亚烷基二醇衍生物，该衍生物至少具有一个由通式表示的组成单元： 其中 R¹ 至 R⁴ 如说明书中所定义。 所述压缩式冰箱润滑油与包括 R-134a 在内的制冷剂具有良好的相溶性。
• Modified polyamine, aqueous epoxy resin curing agent using the same and process for producing thereof
  申请人：MITSUBISHI GAS CHEMICAL COMPANY, INC.

  公开号：EP0742243A2

  公开（公告）日：1996-11-13

  Provided are a modified polyamine which comprises a reaction product between a polyamine and a chlorohydrin synthesized by the reaction of a polyoxyalkylene polyether with an epichlorohydrine and having a total chlorine content of 1,000 ppm or below, and an aqueous epoxy resin curing agent using the same.

  本发明提供了一种改性多胺，该改性多胺由多胺与通过聚氧亚烷基聚醚与环氧氯丙烷反应合成的氯醇之间的反应产物组成，其总氯含量为 1,000 ppm 或以下，还提供了使用该改性多胺的水性环氧树脂固化剂。